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The map label for this gene is gph [H]

Identifier: 160874867

GI number: 160874867

Start: 2101976

End: 2102692

Strand: Direct

Name: gph [H]

Synonym: Sbal195_1752

Alternate gene names: 160874867

Gene position: 2101976-2102692 (Clockwise)

Preceding gene: 160874866

Following gene: 160874869

Centisome position: 39.31

GC content: 46.86

Gene sequence:

>717_bases
ATGAAGACAAAGCAATACGATTTAGTGATTTTCGATTGGGATGGCACTCTGATGGACTCCATCGGTAAAATTATCACCTG
TATTGAAAATATGGCTAAGGCATTACAGTTACCTATCCCAACCGAAAGCGATATTCGCGATATCATCGGTCTTTCTATGA
CTGAAGCGCTGCGAGTCCTGTTTCCTCAGGGGCTCAATCTCAGCGCTTCTTCTGCCTATTCTCAGCGTCAACATCCTAAA
AATGCATTTAGCCAAGGCGAAGATGATCCATATCAGCAGATGCGCATTGAGTTTAAAGCACAATATTTGCATTTAGACAC
CACGCCAACGCCACTCTTTGCACAAGCACCTATTTTAATCGATGAGTTACATGCTCAAGGTTATCAATTAGCCGTTGCAA
CCGGTAAGGCCCGTGCGGGACTTGACCGCGTTTTTGCGCAAACGGGCTTAGGTCGATACTTTGTTGCGTCACGCTGCGCT
GATGAAGTGCACAGCAAACCCCATCCTGAAATGATTTCAAGCTTGCTGAAAGAATTGAATATTGCCCCGAACCGAGCCCT
AATGGTGGGTGATTCTCTGCTGGATTTGACCATGGCGGCCAATGCCGGGATTGATAGTATTGGCGTGACCTATGGCGCCC
ACAGTGCCGAAAAGTTACTGCAAGCAGGACCTATCGCTTTGATTGACTCTCCTGCGCAATTGCTGCAATACCTCTAA

Upstream 100 bases:

>100_bases
AATGATGAAGTGATGCGGGTCTCTGCGCCCTTAGATGAAAACTTGTCGCAATTATTAGATAAGTTAAAGCGTGTGTAATC
GACGGGGATAGGTTTCAAGG

Downstream 100 bases:

>100_bases
CACTACTATTTAATGCTGAAGCGGCAATACATGCCGCTACGCATGAGTACTTGCTGGTTACCTTTATTTACGTCCCATCT
TTCCGTCAATGAAACGAATC

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKTKQYDLVIFDWDGTLMDSIGKIITCIENMAKALQLPIPTESDIRDIIGLSMTEALRVLFPQGLNLSASSAYSQRQHPK
NAFSQGEDDPYQQMRIEFKAQYLHLDTTPTPLFAQAPILIDELHAQGYQLAVATGKARAGLDRVFAQTGLGRYFVASRCA
DEVHSKPHPEMISSLLKELNIAPNRALMVGDSLLDLTMAANAGIDSIGVTYGAHSAEKLLQAGPIALIDSPAQLLQYL

Sequences:

>Translated_238_residues
MKTKQYDLVIFDWDGTLMDSIGKIITCIENMAKALQLPIPTESDIRDIIGLSMTEALRVLFPQGLNLSASSAYSQRQHPK
NAFSQGEDDPYQQMRIEFKAQYLHLDTTPTPLFAQAPILIDELHAQGYQLAVATGKARAGLDRVFAQTGLGRYFVASRCA
DEVHSKPHPEMISSLLKELNIAPNRALMVGDSLLDLTMAANAGIDSIGVTYGAHSAEKLLQAGPIALIDSPAQLLQYL
>Mature_238_residues
MKTKQYDLVIFDWDGTLMDSIGKIITCIENMAKALQLPIPTESDIRDIIGLSMTEALRVLFPQGLNLSASSAYSQRQHPK
NAFSQGEDDPYQQMRIEFKAQYLHLDTTPTPLFAQAPILIDELHAQGYQLAVATGKARAGLDRVFAQTGLGRYFVASRCA
DEVHSKPHPEMISSLLKELNIAPNRALMVGDSLLDLTMAANAGIDSIGVTYGAHSAEKLLQAGPIALIDSPAQLLQYL

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=234, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 26042; Mature: 26042

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKQYDLVIFDWDGTLMDSIGKIITCIENMAKALQLPIPTESDIRDIIGLSMTEALRVL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FPQGLNLSASSAYSQRQHPKNAFSQGEDDPYQQMRIEFKAQYLHLDTTPTPLFAQAPILI
CCCCCCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHEEEEEEECCCCCCCHHCCCHHH
DELHAQGYQLAVATGKARAGLDRVFAQTGLGRYFVASRCADEVHSKPHPEMISSLLKELN
HHHHCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
IAPNRALMVGDSLLDLTMAANAGIDSIGVTYGAHSAEKLLQAGPIALIDSPAQLLQYL
CCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEECCHHHHHHCC
>Mature Secondary Structure
MKTKQYDLVIFDWDGTLMDSIGKIITCIENMAKALQLPIPTESDIRDIIGLSMTEALRVL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FPQGLNLSASSAYSQRQHPKNAFSQGEDDPYQQMRIEFKAQYLHLDTTPTPLFAQAPILI
CCCCCCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHEEEEEEECCCCCCCHHCCCHHH
DELHAQGYQLAVATGKARAGLDRVFAQTGLGRYFVASRCADEVHSKPHPEMISSLLKELN
HHHHCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
IAPNRALMVGDSLLDLTMAANAGIDSIGVTYGAHSAEKLLQAGPIALIDSPAQLLQYL
CCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA