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The map label for this gene is ffh [H]

Identifier: 160874405

GI number: 160874405

Start: 1524089

End: 1525462

Strand: Direct

Name: ffh [H]

Synonym: Sbal195_1286

Alternate gene names: 160874405

Gene position: 1524089-1525462 (Clockwise)

Preceding gene: 160874402

Following gene: 160874406

Centisome position: 28.5

GC content: 49.2

Gene sequence:

>1374_bases
ATGTTTGAGAACCTAACCGACAGACTGTCACGCACACTGAAAAATATCAGTGGCCGTGGTCGCTTAACTGAAGAAAACGT
TAAGGAAACCCTGCGCGAAGTGCGTATGGCACTGCTGGAGGCCGATGTTGCCCTGCCTGTGGTGCGCGAATTCGTTAATA
ATGTAAAAGAACGTGCCGTTGGCCAAGAAGTCTCTAAAAGCTTAAGCCCAGGTCAAGCCTTCATTAAGATAGTTCAAAGT
GAACTTGAAAAATCCATGGGCGAGGCGAATGAAGCCTTAGATTTAGCCACTCAGCCGCCAGCCGTGATCATGATGGCGGG
TCTGCAAGGTGCGGGTAAAACCACCAGTGTGGCCAAACTGGGTAAATTTTTACGCGAACGCCATAAAAAATCGGTATTGG
TGGTCAGTGTCGACGTTTATCGCCCAGCGGCGATCAAACAGCTTGAGACGTTAGCGCAAGAAGTCGCGGTGGAGTTTTTC
CCATCGGACGTTAGCCAAAAGCCAATCGACATTGCGAAAGCGGCGATTGCCCACGCTAAATTAAAGTTCATCGATGTGGT
GATCCTCGATACCGCGGGTCGTCTGCACGTCGACGAAGCCATGATGGACGAGATCAAAGGCTTACACGCTGCGGTCAAGC
CTATCGAGACCTTGTTCGTTGTTGATGCTATGACAGGTCAAGATGCGGCGAACACGGCTAAGGCGTTTAACGAAGCTTTA
CCACTGACAGGGGTTATCTTAACCAAAGTCGATGGTGATGCGCGCGGTGGTGCGGCGTTATCGATTCGCCATATTACCGG
CAAGCCGATTAAATTCCTCGGTGTCGGTGAAAAGACCGACGCGTTAGAACCGTTCCATCCCGATCGTATTGCTTCGCGTA
TTTTGGGTATGGGCGATGTGTTATCGCTTATCGAAGAAGTTGAGCGCGGTGTCGATAAAGAAAAGGCCATGAAACTGGCT
TCGAAAGTGAAGCAGGGTGGCAGTTTTGATTTAGAAGATTTCCGTGAGCAGTTACAGCAAATGAAAAACATGGGCGGCAT
GATGAACATGCTGGAAAAACTGCCCGGTGTGGGTCAATTGCCCCCAGAAGCCTTAGCGCAAATCCAAGACGGCAAGATGA
CAGGCCAAATGGAAGCCATCATTAATTCGATGACGTCCAAAGAGCGTAAGAACCCTGATTTAATCAAGGGTTCACGCAAG
CGTCGTATTGCTGCGGGTTCTGGCACGCAAATCCAAGACGTAAACCGTTTATTGAAACAGTTTACGCAAATGCAAAAGAT
GATGAAAAAAATGTCTGCTAAGGGCGGCATGCAAAAAATGATGCGCGGAATGCGTGGCATGATGCCGCCTGGAATGAAAT
TTCCAGGCCGTTAA

Upstream 100 bases:

>100_bases
ACTTAACCACAATCAAGATGGGTGCAGCAGTAGCATAATGCGCATGCATCGTTATAATACAGCCCATCAATCGAGATTCT
TAAAGGTATAGAACAGGACG

Downstream 100 bases:

>100_bases
TCGGACATTTTTAGTTAAACCTAGCACTTTATCAGTCGGTTGACTCTGGTAACAATGAACCGCTAACGAAGGACGCAGGC
GTAATAATCGCCATCTTTGG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAVGQEVSKSLSPGQAFIKIVQS
ELEKSMGEANEALDLATQPPAVIMMAGLQGAGKTTSVAKLGKFLRERHKKSVLVVSVDVYRPAAIKQLETLAQEVAVEFF
PSDVSQKPIDIAKAAIAHAKLKFIDVVILDTAGRLHVDEAMMDEIKGLHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDVLSLIEEVERGVDKEKAMKLA
SKVKQGGSFDLEDFREQLQQMKNMGGMMNMLEKLPGVGQLPPEALAQIQDGKMTGQMEAIINSMTSKERKNPDLIKGSRK
RRIAAGSGTQIQDVNRLLKQFTQMQKMMKKMSAKGGMQKMMRGMRGMMPPGMKFPGR

Sequences:

>Translated_457_residues
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAVGQEVSKSLSPGQAFIKIVQS
ELEKSMGEANEALDLATQPPAVIMMAGLQGAGKTTSVAKLGKFLRERHKKSVLVVSVDVYRPAAIKQLETLAQEVAVEFF
PSDVSQKPIDIAKAAIAHAKLKFIDVVILDTAGRLHVDEAMMDEIKGLHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDVLSLIEEVERGVDKEKAMKLA
SKVKQGGSFDLEDFREQLQQMKNMGGMMNMLEKLPGVGQLPPEALAQIQDGKMTGQMEAIINSMTSKERKNPDLIKGSRK
RRIAAGSGTQIQDVNRLLKQFTQMQKMMKKMSAKGGMQKMMRGMRGMMPPGMKFPGR
>Mature_457_residues
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAVGQEVSKSLSPGQAFIKIVQS
ELEKSMGEANEALDLATQPPAVIMMAGLQGAGKTTSVAKLGKFLRERHKKSVLVVSVDVYRPAAIKQLETLAQEVAVEFF
PSDVSQKPIDIAKAAIAHAKLKFIDVVILDTAGRLHVDEAMMDEIKGLHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDVLSLIEEVERGVDKEKAMKLA
SKVKQGGSFDLEDFREQLQQMKNMGGMMNMLEKLPGVGQLPPEALAQIQDGKMTGQMEAIINSMTSKERKNPDLIKGSRK
RRIAAGSGTQIQDVNRLLKQFTQMQKMMKKMSAKGGMQKMMRGMRGMMPPGMKFPGR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=452, Percent_Identity=32.7433628318584, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI226371618, Length=354, Percent_Identity=34.4632768361582, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI23308697, Length=298, Percent_Identity=29.1946308724832, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI295424842, Length=298, Percent_Identity=29.1946308724832, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI89061728, Length=160, Percent_Identity=37.5, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1788963, Length=457, Percent_Identity=77.0240700218818, Blast_Score=693, Evalue=0.0,
Organism=Escherichia coli, GI1789874, Length=265, Percent_Identity=34.3396226415094, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17539958, Length=452, Percent_Identity=30.3097345132743, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI193206261, Length=201, Percent_Identity=35.8208955223881, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325345, Length=473, Percent_Identity=31.9238900634249, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6320498, Length=317, Percent_Identity=27.4447949526814, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17647949, Length=443, Percent_Identity=31.1512415349887, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24641198, Length=220, Percent_Identity=29.5454545454545, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49986; Mature: 49986

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS50191 CRAL_TRIO ; PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAV
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVSKSLSPGQAFIKIVQSELEKSMGEANEALDLATQPPAVIMMAGLQGAGKTTSVAKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHH
GKFLRERHKKSVLVVSVDVYRPAAIKQLETLAQEVAVEFFPSDVSQKPIDIAKAAIAHAK
HHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LKFIDVVILDTAGRLHVDEAMMDEIKGLHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
HHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHC
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDV
CCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCHHHH
LSLIEEVERGVDKEKAMKLASKVKQGGSFDLEDFREQLQQMKNMGGMMNMLEKLPGVGQL
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
PPEALAQIQDGKMTGQMEAIINSMTSKERKNPDLIKGSRKRRIAAGSGTQIQDVNRLLKQ
CHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCCCHHHHHHHHHHH
FTQMQKMMKKMSAKGGMQKMMRGMRGMMPPGMKFPGR
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAV
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVSKSLSPGQAFIKIVQSELEKSMGEANEALDLATQPPAVIMMAGLQGAGKTTSVAKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHH
GKFLRERHKKSVLVVSVDVYRPAAIKQLETLAQEVAVEFFPSDVSQKPIDIAKAAIAHAK
HHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LKFIDVVILDTAGRLHVDEAMMDEIKGLHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
HHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHC
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDV
CCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCHHHH
LSLIEEVERGVDKEKAMKLASKVKQGGSFDLEDFREQLQQMKNMGGMMNMLEKLPGVGQL
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
PPEALAQIQDGKMTGQMEAIINSMTSKERKNPDLIKGSRKRRIAAGSGTQIQDVNRLLKQ
CHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCCCHHHHHHHHHHH
FTQMQKMMKKMSAKGGMQKMMRGMRGMMPPGMKFPGR
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]