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The map label for this gene is sseA [H]

Identifier: 160874312

GI number: 160874312

Start: 1415200

End: 1416057

Strand: Direct

Name: sseA [H]

Synonym: Sbal195_1192

Alternate gene names: 160874312

Gene position: 1415200-1416057 (Clockwise)

Preceding gene: 160874311

Following gene: 160874313

Centisome position: 26.47

GC content: 49.88

Gene sequence:

>858_bases
ATGGAATACCCACTAGTAAGTACGCAGTGGCTCGAAGCACACCTCACCGATCCCCATTTAGTCTTGCTCGATGCCAGTAT
GGAAACCGTTATTGGTAAAGAGCCCCTAGTTTACGATGAGCCTATTTGCATTCCGCGCTCACGTCGATTCGACTTGGAAA
ATGTGTTTTGCGATAAGACTTCAACTCAAATCCATGCCTTGCCGACGTTTGAACAATTCAGCCAAGGGATAGCGCAACTT
GGGATTGAGGCCGACAGTGTTATCGTTATCTATGATAACCAAGGCATTTATTCATCTCCACGGGCGTGGTGGACCTTTAA
AGTCATGGGTTTTAATCGAGTCTATGTACTCGATGGTGGCTTGCCTCAGTGGATTGAAGAAGACCGCATCACCTCATCGC
GTTATCAAGCCGAAGGCGTCGATTACGGCCCGACGGATATCGATACATTAGCTGATGTGCTGCAATACCACCCCGAGCGG
GTGATGGATGCCGAGGCCGTGTTATCACGTATTGAAGATGCCGAAACCGCGATTGTCGATGCCCGTGGTGCGCCACGCTT
TTTAGGTCAAGTGAGTGAGCCGCGCCCCGGTGTGCGCTCAGGGCATATTCCTCGTTCTGTTAACTTACCCTTCGCTCAAG
TGCTCGATGGCAATAAAATCAAAACGACCAGTGAGTTACAGGTTATTTATCAAGGATTAGCAGCGGACAAGTCCGCACGG
ATATTTAGCTGTGGCTCTGGGATTACGGCGTGTATTTTGATCTTGGCTTCAGTTGCGGCAGGGCATACAAATCCCATCCT
CTATGATGGCTCGTGGGCGGATTGGGGCAGTCGTACCGATTTGCCAATTGAGTGCTAA

Upstream 100 bases:

>100_bases
TAAAATCCCAAAGCAGACAATTTGTTAAGCCGATATTTGGGCTTTACGGCATTTGGTGAGAGACTAGCGGCAGACTTGGA
TAACAGTAAAAGGACCCGCT

Downstream 100 bases:

>100_bases
TTGGGTAGTTATTGATTGAGTCAGTACAGTTTTGAGCATTATGTCATTACGGTGTCGTAACCGCGGCGTTGTTTGGCTAC
ATCACCAAGGAGGATCCCTT

Product: rhodanese domain-containing protein

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MEYPLVSTQWLEAHLTDPHLVLLDASMETVIGKEPLVYDEPICIPRSRRFDLENVFCDKTSTQIHALPTFEQFSQGIAQL
GIEADSVIVIYDNQGIYSSPRAWWTFKVMGFNRVYVLDGGLPQWIEEDRITSSRYQAEGVDYGPTDIDTLADVLQYHPER
VMDAEAVLSRIEDAETAIVDARGAPRFLGQVSEPRPGVRSGHIPRSVNLPFAQVLDGNKIKTTSELQVIYQGLAADKSAR
IFSCGSGITACILILASVAAGHTNPILYDGSWADWGSRTDLPIEC

Sequences:

>Translated_285_residues
MEYPLVSTQWLEAHLTDPHLVLLDASMETVIGKEPLVYDEPICIPRSRRFDLENVFCDKTSTQIHALPTFEQFSQGIAQL
GIEADSVIVIYDNQGIYSSPRAWWTFKVMGFNRVYVLDGGLPQWIEEDRITSSRYQAEGVDYGPTDIDTLADVLQYHPER
VMDAEAVLSRIEDAETAIVDARGAPRFLGQVSEPRPGVRSGHIPRSVNLPFAQVLDGNKIKTTSELQVIYQGLAADKSAR
IFSCGSGITACILILASVAAGHTNPILYDGSWADWGSRTDLPIEC
>Mature_285_residues
MEYPLVSTQWLEAHLTDPHLVLLDASMETVIGKEPLVYDEPICIPRSRRFDLENVFCDKTSTQIHALPTFEQFSQGIAQL
GIEADSVIVIYDNQGIYSSPRAWWTFKVMGFNRVYVLDGGLPQWIEEDRITSSRYQAEGVDYGPTDIDTLADVLQYHPER
VMDAEAVLSRIEDAETAIVDARGAPRFLGQVSEPRPGVRSGHIPRSVNLPFAQVLDGNKIKTTSELQVIYQGLAADKSAR
IFSCGSGITACILILASVAAGHTNPILYDGSWADWGSRTDLPIEC

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI61835204, Length=285, Percent_Identity=34.0350877192982, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI194473681, Length=285, Percent_Identity=34.0350877192982, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI194473668, Length=285, Percent_Identity=34.0350877192982, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI17402865, Length=287, Percent_Identity=32.7526132404181, Blast_Score=128, Evalue=5e-30,
Organism=Escherichia coli, GI87082121, Length=284, Percent_Identity=35.5633802816901, Blast_Score=184, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI71997283, Length=252, Percent_Identity=26.1904761904762, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17561888, Length=263, Percent_Identity=26.9961977186312, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324825, Length=248, Percent_Identity=33.4677419354839, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 31588; Mature: 31588

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYPLVSTQWLEAHLTDPHLVLLDASMETVIGKEPLVYDEPICIPRSRRFDLENVFCDKT
CCCCCCCHHHHHHCCCCCEEEEEECCHHHHHCCCCCEECCCCCCCCCCCCCHHHEEECCC
STQIHALPTFEQFSQGIAQLGIEADSVIVIYDNQGIYSSPRAWWTFKVMGFNRVYVLDGG
CCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEECC
LPQWIEEDRITSSRYQAEGVDYGPTDIDTLADVLQYHPERVMDAEAVLSRIEDAETAIVD
CHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHCHHHHHCHHHHHHHHHCHHEEEEE
ARGAPRFLGQVSEPRPGVRSGHIPRSVNLPFAQVLDGNKIKTTSELQVIYQGLAADKSAR
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCE
IFSCGSGITACILILASVAAGHTNPILYDGSWADWGSRTDLPIEC
EEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEYPLVSTQWLEAHLTDPHLVLLDASMETVIGKEPLVYDEPICIPRSRRFDLENVFCDKT
CCCCCCCHHHHHHCCCCCEEEEEECCHHHHHCCCCCEECCCCCCCCCCCCCHHHEEECCC
STQIHALPTFEQFSQGIAQLGIEADSVIVIYDNQGIYSSPRAWWTFKVMGFNRVYVLDGG
CCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEECC
LPQWIEEDRITSSRYQAEGVDYGPTDIDTLADVLQYHPERVMDAEAVLSRIEDAETAIVD
CHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHCHHHHHCHHHHHHHHHCHHEEEEE
ARGAPRFLGQVSEPRPGVRSGHIPRSVNLPFAQVLDGNKIKTTSELQVIYQGLAADKSAR
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCE
IFSCGSGITACILILASVAAGHTNPILYDGSWADWGSRTDLPIEC
EEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]