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The map label for this gene is glmS [H]

Identifier: 160874299

GI number: 160874299

Start: 1398496

End: 1399494

Strand: Direct

Name: glmS [H]

Synonym: Sbal195_1179

Alternate gene names: 160874299

Gene position: 1398496-1399494 (Clockwise)

Preceding gene: 160874298

Following gene: 160874300

Centisome position: 26.15

GC content: 49.45

Gene sequence:

>999_bases
ATGACAAACACTATTATGGAGCAAGAAGCTCGCACCGCACCGCAAAAAATCGCTGGCCAGTTAGAAGCTAACGCTGAAAT
CATGCAGCAGTTAGGTGAGAAACTGCGCGCCTTCGATCCCCGTTTTGTAATGATAGTTGGTCGTGGTTCATCGGATCATG
CGGGTGTTTTTGCTAAGTACTTATTTGAAATCGAAGCGGGCGTACCGACGTTTGCCGCCGCCCCTTCAGTGGCGAGTGTG
TATGGTAAGACCTTGAAACTCGAAGGCGCATTAGTGATTGTTATTTCACAATCTGGCCGTAGCCCTGATATTTTGGCGCA
GGCGCGTATGGCAAAAAATGCTGGCGCTTTTTGTGTTGCCTTAGTCAATGATGAAACCGCACCGATTAAAGATATCGTCG
ATGTTGTTGTGCCTTTACGTGCCGGCGAAGAAAAAGCGGTTGCCGCGACTAAGAGTTACCTCGCAACGTTGTCAGCGATT
TTACAGCTTGCCGCCGCTTGGACTCAAAGCGAATCGCTTGCTAGCGCCGTCGCTTCTTTACCCCAAGCGCTGCAAACGGC
GGTGGACGCTGAGCCACAACTCACGCCAGAATCCGTTGCCGACGTGAAGAACTTAGTCGTACTTGGCCGTGGTTTAGGTT
ATGCGGTATCTAAGGAAATTGCGCTTAAGTTAAAAGAAGTGTGTTCAATCCATGCTGAAGCGTTCAGCAGCGCCGAGTTC
CTCCACGGTCCTGTGACCTTAGTTGAGAAAAAACTCACTATCGTTGATGTGTGCATTGGCGATGAATCCTACGCTAGCCA
TATCGAACAGATTGAAAATGTGAGCCAACGCGGCGCCGATTTAGTGCATCTGAATCAAACCTCGACTGACATTCATCCAC
GTGTTGCTCCGTTAGCATTATTACAACGATTCTATATCGATGTGGCTGCGGTTGCGATTGCCCGCGGTATCGATCCCGAT
CAACCTGCTGGCCTTAAAAAAGTGACGCAAACGCTCTAA

Upstream 100 bases:

>100_bases
TCGGTGCTATGTATTTCGCCCAGCAAGAATTTAATAAGTCGTTGTCAGTGCAAATAGGCACTGAAGCCAAATCCTGTATT
TGAACGTGAAGGTAAAAGAC

Downstream 100 bases:

>100_bases
GTTACCGAGCTTTAAGCGGCCAACGTTTTAGAGGTTTAGGTACTGCGGATTAGACTTAGTGGACTTTTAGCTGCACGATT
AAGTCGCTGCACGATTAAAC

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTNTIMEQEARTAPQKIAGQLEANAEIMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKYLFEIEAGVPTFAAAPSVASV
YGKTLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVALVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAI
LQLAAAWTQSESLASAVASLPQALQTAVDAEPQLTPESVADVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
LHGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLALLQRFYIDVAAVAIARGIDPD
QPAGLKKVTQTL

Sequences:

>Translated_332_residues
MTNTIMEQEARTAPQKIAGQLEANAEIMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKYLFEIEAGVPTFAAAPSVASV
YGKTLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVALVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAI
LQLAAAWTQSESLASAVASLPQALQTAVDAEPQLTPESVADVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
LHGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLALLQRFYIDVAAVAIARGIDPD
QPAGLKKVTQTL
>Mature_331_residues
TNTIMEQEARTAPQKIAGQLEANAEIMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKYLFEIEAGVPTFAAAPSVASVY
GKTLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVALVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAIL
QLAAAWTQSESLASAVASLPQALQTAVDAEPQLTPESVADVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEFL
HGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLALLQRFYIDVAAVAIARGIDPDQ
PAGLKKVTQTL

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=365, Percent_Identity=24.6575342465753, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI205277386, Length=317, Percent_Identity=26.1829652996845, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1790167, Length=310, Percent_Identity=29.6774193548387, Blast_Score=115, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17539970, Length=296, Percent_Identity=25.3378378378378, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17532899, Length=253, Percent_Identity=25.6916996047431, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17532897, Length=253, Percent_Identity=25.6916996047431, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322745, Length=335, Percent_Identity=24.4776119402985, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21357745, Length=318, Percent_Identity=25.1572327044025, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35204; Mature: 35073

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTIMEQEARTAPQKIAGQLEANAEIMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKY
CCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
LFEIEAGVPTFAAAPSVASVYGKTLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVA
HHHHHCCCCCHHCCCHHHHHHCCEEEECCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
LVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAILQLAAAWTQSESLASAVASL
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PQALQTAVDAEPQLTPESVADVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLAL
HCCCHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHH
LQRFYIDVAAVAIARGIDPDQPAGLKKVTQTL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
TNTIMEQEARTAPQKIAGQLEANAEIMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKY
CCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
LFEIEAGVPTFAAAPSVASVYGKTLKLEGALVIVISQSGRSPDILAQARMAKNAGAFCVA
HHHHHCCCCCHHCCCHHHHHHCCEEEECCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
LVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAILQLAAAWTQSESLASAVASL
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PQALQTAVDAEPQLTPESVADVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLAL
HCCCHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHH
LQRFYIDVAAVAIARGIDPDQPAGLKKVTQTL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]