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The map label for this gene is ndh [H]

Identifier: 160874289

GI number: 160874289

Start: 1382622

End: 1383911

Strand: Direct

Name: ndh [H]

Synonym: Sbal195_1169

Alternate gene names: 160874289

Gene position: 1382622-1383911 (Clockwise)

Preceding gene: 160874288

Following gene: 160874291

Centisome position: 25.86

GC content: 43.88

Gene sequence:

>1290_bases
TTGGCTACAAAAAGAATAGTGATCGTGGGCGGTGGTGCAGCTGGTTTAGCACTTGCATCTAAGTTGGGCCGTAAATGGGG
CGGTAGTGATGTCGTCGATGTGTGCTTAATTGACCGAAGTCCTATTCATATTTGGAAGCCTAAATTACACGAAGTTGCTG
TTGGCGTGATCGATCAATCTATTGAAGGTTTACTCTACCGCGATCATGGGCTTAAAAATGGTTACCGCTATATTCGCGGT
GAGATAGAGCAGTGCGACCCTGATGCTAAATCGATTCAGTTAGCCGCCGTCTATAATGACGAAGGCGAGTTACTCTTAGA
GCAGCGACAAATCGATTATGATTTTTTAGTCCTTGCTCTTGGTGGTGTTTCTAATAGTTTCAATACATTAGGAGCTGATG
AACACTGCATCTTCTTAGATAGCCTCGAAAATGCCAACCTATTCCACCATAAATTACTCGACGCATTACTCCAATTAAAC
GAAACACAAGAAAGAGTCAGTATTGGCATTGTTGGTGCTGGTGCGACCGGTGTTGAATTGGCGGCAGAACTTCATCATGT
GATTGAATCCGTTAAAGAGTATGGCTATCTGAATATTGCTACACATCATCTTGATGTGCATTTGATTGAAGCATCACCCA
AAATTCTCCCCCAATTACCTGAGCGTGTGAGCGCTAGGGCGCAGGCAGTTCTTGATAAGATAGGTATACGTTTACATATC
GGTGTTCAAGTTAAAGAAGTGACTCGTGATGGTTTTATTACCCAAGATGGGGATGTGATTAAAGCGGGCTTAAAAGTCTG
GGCGGCAGGTGTAAAAGGGCCAAAAGCGTTTCAGAACTTTACAAAATTGCCCATTACGCCGCGAAATCAGGTTGAAGTTG
ATGACTGCATGCGAGTCAAGGGCCATCAAGATATTTACGCCCTTGGCGATTGCGCTCTATTGATCCAAAGTTCTGGTCAG
CCTGTTCCACCAAGGGCGCAAGCTGCGGCACAGATGGCTGATACTTTGTTTGATAATATCGTTAATCGATTACAAGGTAA
GCCTGAAAAGGCCTTTGTTTACAAAGATTACGGTTCATTAGTGTCTTTAAGCCGCTTCTCTGCGGTAGGTAATTTGATGG
GGAACCTACGCTCTGGCACTTTCTTTGTCGAAGGGCATATTGCAAGATTGATGTATATCTCTTTGTATCAGAGGCATTTA
GCCAGCCTTTATGGTTGGTTTTCGGCAATAGTGTATCGAGTGGCACAAAAGTTATTGAGGTGGCAGCGTCCAAAGCTCAA
ATTACATTGA

Upstream 100 bases:

>100_bases
TTAATGCAAAATCGTCAGTTTTACTGAACTAATGTAGTTATCTCTTATCTGTAACATGGTATAACTGAGCCTCGCAAATG
AGTTTTATGAGGTTGTCATT

Downstream 100 bases:

>100_bases
TTTCTATGTAATGTAGGGCAAAAAAGAGAGCAAATATGCTCTCTTTTTTTATTGTTTAGGAATTGCTGACGAGTCACGAA
TGATAGGTTCAGGTGTAAAG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MATKRIVIVGGGAAGLALASKLGRKWGGSDVVDVCLIDRSPIHIWKPKLHEVAVGVIDQSIEGLLYRDHGLKNGYRYIRG
EIEQCDPDAKSIQLAAVYNDEGELLLEQRQIDYDFLVLALGGVSNSFNTLGADEHCIFLDSLENANLFHHKLLDALLQLN
ETQERVSIGIVGAGATGVELAAELHHVIESVKEYGYLNIATHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHI
GVQVKEVTRDGFITQDGDVIKAGLKVWAAGVKGPKAFQNFTKLPITPRNQVEVDDCMRVKGHQDIYALGDCALLIQSSGQ
PVPPRAQAAAQMADTLFDNIVNRLQGKPEKAFVYKDYGSLVSLSRFSAVGNLMGNLRSGTFFVEGHIARLMYISLYQRHL
ASLYGWFSAIVYRVAQKLLRWQRPKLKLH

Sequences:

>Translated_429_residues
MATKRIVIVGGGAAGLALASKLGRKWGGSDVVDVCLIDRSPIHIWKPKLHEVAVGVIDQSIEGLLYRDHGLKNGYRYIRG
EIEQCDPDAKSIQLAAVYNDEGELLLEQRQIDYDFLVLALGGVSNSFNTLGADEHCIFLDSLENANLFHHKLLDALLQLN
ETQERVSIGIVGAGATGVELAAELHHVIESVKEYGYLNIATHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHI
GVQVKEVTRDGFITQDGDVIKAGLKVWAAGVKGPKAFQNFTKLPITPRNQVEVDDCMRVKGHQDIYALGDCALLIQSSGQ
PVPPRAQAAAQMADTLFDNIVNRLQGKPEKAFVYKDYGSLVSLSRFSAVGNLMGNLRSGTFFVEGHIARLMYISLYQRHL
ASLYGWFSAIVYRVAQKLLRWQRPKLKLH
>Mature_428_residues
ATKRIVIVGGGAAGLALASKLGRKWGGSDVVDVCLIDRSPIHIWKPKLHEVAVGVIDQSIEGLLYRDHGLKNGYRYIRGE
IEQCDPDAKSIQLAAVYNDEGELLLEQRQIDYDFLVLALGGVSNSFNTLGADEHCIFLDSLENANLFHHKLLDALLQLNE
TQERVSIGIVGAGATGVELAAELHHVIESVKEYGYLNIATHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHIG
VQVKEVTRDGFITQDGDVIKAGLKVWAAGVKGPKAFQNFTKLPITPRNQVEVDDCMRVKGHQDIYALGDCALLIQSSGQP
VPPRAQAAAQMADTLFDNIVNRLQGKPEKAFVYKDYGSLVSLSRFSAVGNLMGNLRSGTFFVEGHIARLMYISLYQRHLA
SLYGWFSAIVYRVAQKLLRWQRPKLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=429, Percent_Identity=44.988344988345, Blast_Score=367, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6323515, Length=462, Percent_Identity=28.1385281385281, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320118, Length=449, Percent_Identity=25.8351893095768, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323794, Length=355, Percent_Identity=27.3239436619718, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47362; Mature: 47231

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKRIVIVGGGAAGLALASKLGRKWGGSDVVDVCLIDRSPIHIWKPKLHEVAVGVIDQS
CCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHH
IEGLLYRDHGLKNGYRYIRGEIEQCDPDAKSIQLAAVYNDEGELLLEQRQIDYDFLVLAL
HHHHEEECCCCCCCHHHHCCCHHHCCCCCCCEEEEEEECCCCCEEHHHHCCCCEEEEEEE
GGVSNSFNTLGADEHCIFLDSLENANLFHHKLLDALLQLNETQERVSIGIVGAGATGVEL
CCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHEEEEEEECCCCHHHH
AAELHHVIESVKEYGYLNIATHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHI
HHHHHHHHHHHHHCCEEEEEEEEEEEEEEECCCCHHHHCHHHHHHHHHHHHHHCCEEEEE
GVQVKEVTRDGFITQDGDVIKAGLKVWAAGVKGPKAFQNFTKLPITPRNQVEVDDCMRVK
CEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHCC
GHQDIYALGDCALLIQSSGQPVPPRAQAAAQMADTLFDNIVNRLQGKPEKAFVYKDYGSL
CCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
VSLSRFSAVGNLMGNLRSGTFFVEGHIARLMYISLYQRHLASLYGWFSAIVYRVAQKLLR
HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQRPKLKLH
CCCCCCCCC
>Mature Secondary Structure 
ATKRIVIVGGGAAGLALASKLGRKWGGSDVVDVCLIDRSPIHIWKPKLHEVAVGVIDQS
CCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHH
IEGLLYRDHGLKNGYRYIRGEIEQCDPDAKSIQLAAVYNDEGELLLEQRQIDYDFLVLAL
HHHHEEECCCCCCCHHHHCCCHHHCCCCCCCEEEEEEECCCCCEEHHHHCCCCEEEEEEE
GGVSNSFNTLGADEHCIFLDSLENANLFHHKLLDALLQLNETQERVSIGIVGAGATGVEL
CCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHEEEEEEECCCCHHHH
AAELHHVIESVKEYGYLNIATHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHI
HHHHHHHHHHHHHCCEEEEEEEEEEEEEEECCCCHHHHCHHHHHHHHHHHHHHCCEEEEE
GVQVKEVTRDGFITQDGDVIKAGLKVWAAGVKGPKAFQNFTKLPITPRNQVEVDDCMRVK
CEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHCC
GHQDIYALGDCALLIQSSGQPVPPRAQAAAQMADTLFDNIVNRLQGKPEKAFVYKDYGSL
CCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
VSLSRFSAVGNLMGNLRSGTFFVEGHIARLMYISLYQRHLASLYGWFSAIVYRVAQKLLR
HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQRPKLKLH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]