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The map label for this gene is lspA [H]

Identifier: 160874277

GI number: 160874277

Start: 1372271

End: 1372786

Strand: Direct

Name: lspA [H]

Synonym: Sbal195_1157

Alternate gene names: 160874277

Gene position: 1372271-1372786 (Clockwise)

Preceding gene: 160874276

Following gene: 160874278

Centisome position: 25.66

GC content: 42.25

Gene sequence:

>516_bases
ATGCCATTAACTTGGAAAGACAGTGGCTTACGTTGGTATTGGGTAGCTGTATTGGTGTTTTTCGCCGATCAGCTATCTAA
ACAATGGGTCTTAGCCAATTTTGATTTGCATGAATCGCTGAATTTATTGCCTTTCTTTAATTTCACTTATGTACGTAACT
ACGGGGCCGCCTTTAGTTTTTTAAGTGACGCCGGTGGTTGGCAGCGTTGGTTATTTACGATTGTTGCGGTTGGATTCAGC
ACTCTACTAACAGTGTGGTTGCGTAAGCAATCTGCTTCGTTGTTGAAACTGAATCTGGCTTACACCTTAGTGATTGGTGG
TGCCCTAGGCAATTTGGTCGACAGATTAATGCACGGTTTTGTGGTTGATTTTATCGATTTTTTTTGGGCTAAGAGCCACT
ATCCAGCTTTCAATATCGCCGATTCGGCGATTTGTATTGGTGCTGTGTTGATCATTTGGGATGCATTTTTAAGCGGTAAA
TCTGAAACAGATAGCGCCGAAGGGGTTAAAAAGTGA

Upstream 100 bases:

>100_bases
AGAGGTTGGCACTATCGAGGCCCACCCAACACTCTGTACTCGCTGCGTAACAAACATTGAAGGTGACGGCGAAGTTCGTC
TGTTTGCGTAAAGGATCTGT

Downstream 100 bases:

>100_bases
CGGTGACGCGATCTTTACTATGCCATATGAATATTGTGCTTTCTGATGGTTCAACCGCAGACAGCACTAAAGCTTCGGGT
AAACCAGCTCGATTAAATGT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPLTWKDSGLRWYWVAVLVFFADQLSKQWVLANFDLHESLNLLPFFNFTYVRNYGAAFSFLSDAGGWQRWLFTIVAVGFS
TLLTVWLRKQSASLLKLNLAYTLVIGGALGNLVDRLMHGFVVDFIDFFWAKSHYPAFNIADSAICIGAVLIIWDAFLSGK
SETDSAEGVKK

Sequences:

>Translated_171_residues
MPLTWKDSGLRWYWVAVLVFFADQLSKQWVLANFDLHESLNLLPFFNFTYVRNYGAAFSFLSDAGGWQRWLFTIVAVGFS
TLLTVWLRKQSASLLKLNLAYTLVIGGALGNLVDRLMHGFVVDFIDFFWAKSHYPAFNIADSAICIGAVLIIWDAFLSGK
SETDSAEGVKK
>Mature_170_residues
PLTWKDSGLRWYWVAVLVFFADQLSKQWVLANFDLHESLNLLPFFNFTYVRNYGAAFSFLSDAGGWQRWLFTIVAVGFST
LLTVWLRKQSASLLKLNLAYTLVIGGALGNLVDRLMHGFVVDFIDFFWAKSHYPAFNIADSAICIGAVLIIWDAFLSGKS
ETDSAEGVKK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=164, Percent_Identity=49.390243902439, Blast_Score=167, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19331; Mature: 19199

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTWKDSGLRWYWVAVLVFFADQLSKQWVLANFDLHESLNLLPFFNFTYVRNYGAAFSF
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHH
LSDAGGWQRWLFTIVAVGFSTLLTVWLRKQSASLLKLNLAYTLVIGGALGNLVDRLMHGF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDFIDFFWAKSHYPAFNIADSAICIGAVLIIWDAFLSGKSETDSAEGVKK
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLTWKDSGLRWYWVAVLVFFADQLSKQWVLANFDLHESLNLLPFFNFTYVRNYGAAFSF
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHH
LSDAGGWQRWLFTIVAVGFSTLLTVWLRKQSASLLKLNLAYTLVIGGALGNLVDRLMHGF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDFIDFFWAKSHYPAFNIADSAICIGAVLIIWDAFLSGKSETDSAEGVKK
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA