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The map label for this gene is obgE

Identifier: 160874191

GI number: 160874191

Start: 1269335

End: 1270504

Strand: Direct

Name: obgE

Synonym: Sbal195_1071

Alternate gene names: 160874191

Gene position: 1269335-1270504 (Clockwise)

Preceding gene: 160874190

Following gene: 160874192

Centisome position: 23.74

GC content: 47.09

Gene sequence:

>1170_bases
ATGAAGTTTGTCGATGAGGCAGTAATTAGGGTCGAAGCAGGCGACGGCGGTAGCGGTTGTGTTAGCTTTAGGCGCGAAAA
GTATGTACCTGATGGTGGTCCTGATGGTGGTGATGGTGGCGACGGCGGCAGTGTTTTCCTGCAAGCTGACGAAAACTTCA
ACACCTTGATCGAGTTCCGTTTTGAACGTTTTCACATGGCTGAACGTGGCGAAAATGGTCGTGGCCGTGATTGTACCGGT
CACAGCGGTAAAGATCTGATCTTAAAAGTTCCTGTTGGTACTCGCGCGGTCGATCATGATACTGAAGAAGTCCTTGGGGA
TTTAACGACCCACGGTCAAAAGCTATTGGTTGCCAAAGGTGGTTTCCATGGTTTAGGTAACACCCGTTTTAAGAGCAGTA
CTAACCGTGCCCCACGTCAAAAGACGTTAGGAACACCTGGTGAAGTTCGTAGCCTTAAATTAGAGTTGTTACTGTTGGCT
GACGTTGGTTTGCTTGGCATGCCTAACGCGGGTAAGTCGACATTCATTCGTGCGGTTTCCCGTGCAACGCCTAAAGTGGC
TGATTATCCGTTTACAACACTAGTGCCTAACTTAGGTGTGGTTAATCCACGTCCTGGTCAAAGCTTTGTGATCGCGGATA
TTCCAGGTCTTATCGAAGGCGCTGCCGATGGTGCGGGTTTAGGTATTCGCTTCTTAAAGCATCTTGAGCGTTGTCGTATT
CTACTGCACATCATCGACATTGAGCCTATTGACGGAACCGATCCGGTTGAGTCTGCACGCGCTATCGTTGGTGAGCTTGA
GAAATACTCTCCAAAACTGGCAAGCAAGCCACGTTGGTTAGTCTTTAACAAAACCGATTTGCTGCTTGAAGAAGAGCTGC
AACAAAAGGTTGATCGCATCGTTAAAGAAATGGGTTGGGAAGGCGACGTTTACACTATTTCTGCCTACAACCGCGACGGC
ACTAATGAGTTGGCATTAAAGCTCCTCGATTATATTGCGAGCCTGCCACCAGAAGACAATGAAATCGACCCAGACAGTGA
AGTCGAGTTCAAGTGGGATAATTATCATCAAGCTAACTTAGATTCTGTGAATGAAGACTATGTTGATGAAGATGATGACG
ACGACTTTGATGATGACGACTACGACGTAGAAGTTATTTACCAGAGATAA

Upstream 100 bases:

>100_bases
GCATTGACAGGTAAGATTGGGAGCAAAGTATCTCGAGTTTTTTGGCGACCAATGAAGTTAGACGGTATAATTGCTTCATT
CAGTGATGCCAGGAGTAAGT

Downstream 100 bases:

>100_bases
TCTTACCGTCTTAATTTTGAGAGTTCCGTGTACGCAGATACTCAAAATGATATTACTCGGCAAGTTGTGCGTGCTGCACA
ACTGCTACTGGCCTACGGCG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKFVDEAVIRVEAGDGGSGCVSFRREKYVPDGGPDGGDGGDGGSVFLQADENFNTLIEFRFERFHMAERGENGRGRDCTG
HSGKDLILKVPVGTRAVDHDTEEVLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGIRFLKHLERCRI
LLHIIDIEPIDGTDPVESARAIVGELEKYSPKLASKPRWLVFNKTDLLLEEELQQKVDRIVKEMGWEGDVYTISAYNRDG
TNELALKLLDYIASLPPEDNEIDPDSEVEFKWDNYHQANLDSVNEDYVDEDDDDDFDDDDYDVEVIYQR

Sequences:

>Translated_389_residues
MKFVDEAVIRVEAGDGGSGCVSFRREKYVPDGGPDGGDGGDGGSVFLQADENFNTLIEFRFERFHMAERGENGRGRDCTG
HSGKDLILKVPVGTRAVDHDTEEVLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGIRFLKHLERCRI
LLHIIDIEPIDGTDPVESARAIVGELEKYSPKLASKPRWLVFNKTDLLLEEELQQKVDRIVKEMGWEGDVYTISAYNRDG
TNELALKLLDYIASLPPEDNEIDPDSEVEFKWDNYHQANLDSVNEDYVDEDDDDDFDDDDYDVEVIYQR
>Mature_389_residues
MKFVDEAVIRVEAGDGGSGCVSFRREKYVPDGGPDGGDGGDGGSVFLQADENFNTLIEFRFERFHMAERGENGRGRDCTG
HSGKDLILKVPVGTRAVDHDTEEVLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGIRFLKHLERCRI
LLHIIDIEPIDGTDPVESARAIVGELEKYSPKLASKPRWLVFNKTDLLLEEELQQKVDRIVKEMGWEGDVYTISAYNRDG
TNELALKLLDYIASLPPEDNEIDPDSEVEFKWDNYHQANLDSVNEDYVDEDDDDDFDDDDYDVEVIYQR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=331, Percent_Identity=40.4833836858006, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI111955139, Length=232, Percent_Identity=39.6551724137931, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI111955063, Length=126, Percent_Identity=43.6507936507937, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=34.6456692913386, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI58761500, Length=130, Percent_Identity=31.5384615384615, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=390, Percent_Identity=65.3846153846154, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=35, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=285, Percent_Identity=41.0526315789474, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=31.7152103559871, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=34.375, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=32.2033898305085, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=35.5670103092784, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=32.03125, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129375, Length=314, Percent_Identity=40.7643312101911, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24585318, Length=289, Percent_Identity=37.7162629757785, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=32.5581395348837, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=32.5581395348837, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=32.5581395348837, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=30.7086614173228, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_SHEB2 (B8EC04)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002359228.1
- ProteinModelPortal:   B8EC04
- SMR:   B8EC04
- GeneID:   7087147
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_3321
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12298
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 42921; Mature: 42921

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAVIRVEAGDGGSGCVSFRREKYVPDGGPDGGDGGDGGSVFLQADENFNTLIEFR
CCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
FERFHMAERGENGRGRDCTGHSGKDLILKVPVGTRAVDHDTEEVLGDLTTHGQKLLVAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLADVGLLGMPNAGKSTFIRAVS
CCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHEEEEEEEEECCCEECCCCCCHHHHHHHHH
RATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGIRFLKHLERCRI
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEE
LLHIIDIEPIDGTDPVESARAIVGELEKYSPKLASKPRWLVFNKTDLLLEEELQQKVDRI
EEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCEEEECCCHHHHHHHHHHHHHHH
VKEMGWEGDVYTISAYNRDGTNELALKLLDYIASLPPEDNEIDPDSEVEFKWDNYHQANL
HHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCC
DSVNEDYVDEDDDDDFDDDDYDVEVIYQR
CCCCCCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKFVDEAVIRVEAGDGGSGCVSFRREKYVPDGGPDGGDGGDGGSVFLQADENFNTLIEFR
CCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
FERFHMAERGENGRGRDCTGHSGKDLILKVPVGTRAVDHDTEEVLGDLTTHGQKLLVAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLADVGLLGMPNAGKSTFIRAVS
CCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHEEEEEEEEECCCEECCCCCCHHHHHHHHH
RATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGIRFLKHLERCRI
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEE
LLHIIDIEPIDGTDPVESARAIVGELEKYSPKLASKPRWLVFNKTDLLLEEELQQKVDRI
EEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCEEEECCCHHHHHHHHHHHHHHH
VKEMGWEGDVYTISAYNRDGTNELALKLLDYIASLPPEDNEIDPDSEVEFKWDNYHQANL
HHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCC
DSVNEDYVDEDDDDDFDDDDYDVEVIYQR
CCCCCCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA