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The map label for this gene is pbpG [H]

Identifier: 160874112

GI number: 160874112

Start: 1175638

End: 1176603

Strand: Direct

Name: pbpG [H]

Synonym: Sbal195_0992

Alternate gene names: 160874112

Gene position: 1175638-1176603 (Clockwise)

Preceding gene: 160874111

Following gene: 160874113

Centisome position: 21.99

GC content: 46.27

Gene sequence:

>966_bases
ATGAAGATCCGTTTTCTGCTCAGTAGTTTTATTCTTGTATGCAGCAGTCTAACTGTTGCCGCGACAGCGCATTCAGCCGA
TTCGGCCTCTGTCACTACTAAACATGCCAGCAAAAATGCACCCGCTAAAAAAGCACCTGCAAAACAGCAAGAAGTGGCAT
CGAGTAGCGCTATGGTGGTCGACCTTAAAACCAATGAAGTTTTATATTCGAGTAACCCTAATGCAGTGGTGCCCATCGCC
TCAGTGACTAAGCTGATGACGGCCATGGTGACCTTAGATGCAAAGCTGGCGATGGACGAAAAGTTAGCGGTTAATATTAA
CGACACCAAAGAAATGCGCGGCGTATATTCTAGAGTGCGTATCGGCAGTGAAATTAGCCGTAAAGACATGTTATTGCTGA
CCTTAATGTCATCAGAAAACCGCGCAGCAGCCAGCCTTGCCCACCATTATCCCGGTGGTCACAAAGCCTTTATTAAGGCG
ATGAATGCCAAAGCTAAAGCACTGGGCATGAAGAATACCCGTTATGTTGAACCGACAGGTTTGTCATACAAAAACGTCTC
CAGTGCCAGCGACCTGATTGTGCTGCTTAAGGCCAGTGAAGGTTATCCTATGCTAGGCCAATTGAGTTCGACCGAGAAAA
AGACGGTCACCTTTGCTAAACCGAGATACAGTTTAGATTTCCGCAACACTAACCGTTTGGTTTATAAAGATAACTGGAAT
ATACATCTCACTAAAACCGGTTTTACTAACGAAGCGGGGCATTGCTTAGTGATGCGCACCGAAATGGCAAAACGCCAAGT
GGCCTTTGTGGTACTCGATGCCTACGGTAAATATACCCATATCGCCGATGCAAACCGTTTACGTAACTGGTTAGAAACAG
GCAAAGTCACCCCGATCCCAGCCGAAGCTAAGCAATATAAGAAACAGCGTAGCCAGCAGCAATTAGCTAAGTTGAGTGAG
ACCTAG

Upstream 100 bases:

>100_bases
AGTCTAATTGCATTCTATTTCTTTCACGGTAGAACTCCTATACTTAGCCAAACCTTGTGCCATAGCACAATCGATCCCTT
ATCTATTCAGTGAAATCTAA

Downstream 100 bases:

>100_bases
GCTTTGACCTAGAAGTCGAGCTGGAGCATATCTCTTGCTTTAACGGCTTTATAAAGACTAAAAAACCAAAGGCCAGATGA
GCAATCCATCTGGCCTTTGG

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKIRFLLSSFILVCSSLTVAATAHSADSASVTTKHASKNAPAKKAPAKQQEVASSSAMVVDLKTNEVLYSSNPNAVVPIA
SVTKLMTAMVTLDAKLAMDEKLAVNINDTKEMRGVYSRVRIGSEISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKA
MNAKAKALGMKNTRYVEPTGLSYKNVSSASDLIVLLKASEGYPMLGQLSSTEKKTVTFAKPRYSLDFRNTNRLVYKDNWN
IHLTKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHIADANRLRNWLETGKVTPIPAEAKQYKKQRSQQQLAKLSE
T

Sequences:

>Translated_321_residues
MKIRFLLSSFILVCSSLTVAATAHSADSASVTTKHASKNAPAKKAPAKQQEVASSSAMVVDLKTNEVLYSSNPNAVVPIA
SVTKLMTAMVTLDAKLAMDEKLAVNINDTKEMRGVYSRVRIGSEISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKA
MNAKAKALGMKNTRYVEPTGLSYKNVSSASDLIVLLKASEGYPMLGQLSSTEKKTVTFAKPRYSLDFRNTNRLVYKDNWN
IHLTKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHIADANRLRNWLETGKVTPIPAEAKQYKKQRSQQQLAKLSE
T
>Mature_321_residues
MKIRFLLSSFILVCSSLTVAATAHSADSASVTTKHASKNAPAKKAPAKQQEVASSSAMVVDLKTNEVLYSSNPNAVVPIA
SVTKLMTAMVTLDAKLAMDEKLAVNINDTKEMRGVYSRVRIGSEISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKA
MNAKAKALGMKNTRYVEPTGLSYKNVSSASDLIVLLKASEGYPMLGQLSSTEKKTVTFAKPRYSLDFRNTNRLVYKDNWN
IHLTKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHIADANRLRNWLETGKVTPIPAEAKQYKKQRSQQQLAKLSE
T

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=258, Percent_Identity=70.9302325581395, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1787062, Length=286, Percent_Identity=29.7202797202797, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082022, Length=272, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 35306; Mature: 35306

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRFLLSSFILVCSSLTVAATAHSADSASVTTKHASKNAPAKKAPAKQQEVASSSAMVV
CCHHHHHHHHHHHHCCHHEEEEECCCCCCCEEECCCCCCCCCCCCCCHHHHHCCCCEEEE
DLKTNEVLYSSNPNAVVPIASVTKLMTAMVTLDAKLAMDEKLAVNINDTKEMRGVYSRVR
EEECCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
IGSEISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKAMNAKAKALGMKNTRYVEPTG
CCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCCEEECCCC
LSYKNVSSASDLIVLLKASEGYPMLGQLSSTEKKTVTFAKPRYSLDFRNTNRLVYKDNWN
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCEEEEECCCE
IHLTKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHIADANRLRNWLETGKVTPIP
EEEEECCCCCCCCCEEEEECHHHHHEEEEEEEECCCCEEECCCHHHHHHHHHHCCCCCCC
AEAKQYKKQRSQQQLAKLSET
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIRFLLSSFILVCSSLTVAATAHSADSASVTTKHASKNAPAKKAPAKQQEVASSSAMVV
CCHHHHHHHHHHHHCCHHEEEEECCCCCCCEEECCCCCCCCCCCCCCHHHHHCCCCEEEE
DLKTNEVLYSSNPNAVVPIASVTKLMTAMVTLDAKLAMDEKLAVNINDTKEMRGVYSRVR
EEECCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
IGSEISRKDMLLLTLMSSENRAAASLAHHYPGGHKAFIKAMNAKAKALGMKNTRYVEPTG
CCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCCEEECCCC
LSYKNVSSASDLIVLLKASEGYPMLGQLSSTEKKTVTFAKPRYSLDFRNTNRLVYKDNWN
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCEEEEECCCE
IHLTKTGFTNEAGHCLVMRTEMAKRQVAFVVLDAYGKYTHIADANRLRNWLETGKVTPIP
EEEEECCCCCCCCCEEEEECHHHHHEEEEEEEECCCCEEECCCHHHHHHHHHHCCCCCCC
AEAKQYKKQRSQQQLAKLSET
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]