Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 160874086

GI number: 160874086

Start: 1146265

End: 1148163

Strand: Reverse

Name: zraS [C]

Synonym: Sbal195_0966

Alternate gene names: 160874086

Gene position: 1148163-1146265 (Counterclockwise)

Preceding gene: 160874087

Following gene: 160874080

Centisome position: 21.47

GC content: 46.5

Gene sequence:

>1899_bases
ATGACAGCGCCATCGCAATTGACTCAGCCTACCTTCTGGGGCTACTGGCTCAGATTCATGCTGCCGTGGTTATTGTTGGT
GCCCATACTCACCACTTTGCTTTATCAAAAGCGCCATGAAGATGCCATGGTGCCCTTATACCAAGAGGCGAACACCCTTT
TAGGTGATGCCGCTAAAACCATTGCCTACCATATTGGTAATATTAAGCGCGACGCCCTATTTCTTGCTAAATATCAAACA
CTCCTCGATGCGGCGGCGGGAAATGAGCAAGATCTCACTCAGGTCGAACATTTCTTCGAGAGCTTTAGCGCCGCATCACA
AAACTACGATCAAGTACGTTGGCTCGATAATAACGCCTTAGAAAAAGTCAGAGTCAATCTTGTCCAGAATCTCCCACACA
TAGTTGCTAAACCATTATTACAATTGAAGGCTAAGCGATATTACGCCATCCAGAGTTTAAGCTTAGCCCCTAATAGTTTT
TACTTTTCGCCCTTAGATTTGAATGTCGAAAAGGGAGAAATAGAAAATCCAATCAAGCCCGTATTAAGAGTCACCACTCC
CGTATTTTTACCTTCAGGCGAGCGCCAAGGCTTTATTGCCCTCAATTTTCTCGCCCAATCAATGTTAGACGCCATTGCCA
AAATTACGGCTAACAGCAATGTCGAGCTTTCACTGCTGAATAAAGAGGGTTACTGGCTACTCTCATCCAATTCCGAACTC
ACTTGGGCATTTATGTTTAATCGCCCCGAATTAACCTTAGCTAAGCTCAATCCCGATGCCTGGCAACAGATTACCCAAGA
TAGCGAAGGTGCTTTTATCACCCCCGAAGGGCTCTGGGATTATGAAAATGTACAAGATGCGACCAACACTTCTGACCAAG
ATTGGAAACTCGTGATACGGGTTCCCAATGATCAACTTTCAAAGATTAATCAACGCAGCCTGCTGGAAGCGCTCAGTCTA
GGGATTTTATTACTATTACTCGGCGGTGGGATCTGCTGGCGCGCAGCAAAGTCCATGCGAGTAAGGGACAAGTTGAATCA
AGAGTTAACCGAGCAACAGCAAAAACTCACCCAATCCAATACCGCGTTAGCCGAATCGTTACAGCACTTACACGACACTC
AGCAACAACTCATCGAGACGGGAAAACTCTCATCCTTAGGCATGATGGTGGCGGGCGTCGCCCATGAACTCAATACCCCT
GTCGGCGCTGCACAGGTCACGTTATCGAGCATGAAAAATGAATGCACTAAGCTACAAAACGCCTTCGAATCGGGTCTTAA
GCGATCTGATGTCGATACTTACTTTATTCACTTCCATGAAGGCGCGGAGATAGTGCAAGCCAATTTAAGCAGAGCCGCAA
CCTTAGTCAGTAGCTTCAAACGCTTAGCCGTGGATAGAACAAGGGAAGAACGCCGTAGTTTTAAGCTCACAAGTCTCGTT
CAGGACATGCTACATACCTCATGGCTACGGATGAAGAAGCAATCCCATGAGCTCGAAATCGACATTGATGCCAATATCGA
AATGAACAGCTACCCAGGCGCACTCGGACAATCCCTTGAAAACTTCGTCACTAATGCGATAACCCATGCTTTCGAAGGAA
GGGGAAATGGCCAGATAAAAATCTCGGCAAAGATGATAGAAGATCAAATAGTCGAAATCACAGTCTCAGACAATGGCATA
GGGATGAGCGCGGAAACGATGAAACAAATCTTCGACCCCTTCTTTACCACTCGCAGGGGAAATGGCGGAACTGGGCTGGG
GTTACACTTAACTTATCAACTCGTCAGCCAACTTCTTGGCGGGAAAATTACGGTCAGCAGTAAGTTAGGTAAAGGCAGCG
TTTTCAGCCTGATAATCCCAGTAACAGCGCCAGAAACCGCCGAGCTGAACCTGAATTAA

Upstream 100 bases:

>100_bases
GCGACCGCGGCTGCCACGATGCCCAAGGCTACTTTTATGCTAAGCCCATGCCACTACCGGAGTTATTAACTTGGCTTAAA
AACTACCAAAAAACACCACT

Downstream 100 bases:

>100_bases
CCGGTTATACGCAACAGCGATAGATAGCCAATATGCTGGCCGAATATGATGCTAAAACTTGATGCCTAAACATGATGCTT
GAACTATGGTGTTTGAATAT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MTAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKTIAYHIGNIKRDALFLAKYQT
LLDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNALEKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSF
YFSPLDLNVEKGEIENPIKPVLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNSEL
TWAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIRVPNDQLSKINQRSLLEALSL
GILLLLLGGGICWRAAKSMRVRDKLNQELTEQQQKLTQSNTALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTP
VGAAQVTLSSMKNECTKLQNAFESGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLV
QDMLHTSWLRMKKQSHELEIDIDANIEMNSYPGALGQSLENFVTNAITHAFEGRGNGQIKISAKMIEDQIVEITVSDNGI
GMSAETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLGGKITVSSKLGKGSVFSLIIPVTAPETAELNLN

Sequences:

>Translated_632_residues
MTAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKTIAYHIGNIKRDALFLAKYQT
LLDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNALEKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSF
YFSPLDLNVEKGEIENPIKPVLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNSEL
TWAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIRVPNDQLSKINQRSLLEALSL
GILLLLLGGGICWRAAKSMRVRDKLNQELTEQQQKLTQSNTALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTP
VGAAQVTLSSMKNECTKLQNAFESGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLV
QDMLHTSWLRMKKQSHELEIDIDANIEMNSYPGALGQSLENFVTNAITHAFEGRGNGQIKISAKMIEDQIVEITVSDNGI
GMSAETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLGGKITVSSKLGKGSVFSLIIPVTAPETAELNLN
>Mature_631_residues
TAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKTIAYHIGNIKRDALFLAKYQTL
LDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNALEKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSFY
FSPLDLNVEKGEIENPIKPVLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNSELT
WAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIRVPNDQLSKINQRSLLEALSLG
ILLLLLGGGICWRAAKSMRVRDKLNQELTEQQQKLTQSNTALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTPV
GAAQVTLSSMKNECTKLQNAFESGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLVQ
DMLHTSWLRMKKQSHELEIDIDANIEMNSYPGALGQSLENFVTNAITHAFEGRGNGQIKISAKMIEDQIVEITVSDNGIG
MSAETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLGGKITVSSKLGKGSVFSLIIPVTAPETAELNLN

Specific function: Member Of The Two-Component Regulatory System Zras/Zrar. May Function As A Membrane-Associated Protein Kinase That Phosphorylates Zrar In Response To High Concentrations Of Zinc Or Lead In The Medium. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=31.0756972111554, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=28, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789149, Length=281, Percent_Identity=26.3345195729537, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70644; Mature: 70512

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IAYHIGNIKRDALFLAKYQTLLDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNAL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHH
EKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSFYFSPLDLNVEKGEIENPIKP
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCEECCCCCCCCCCHHHH
VLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNSEL
HHHHHCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCE
TWAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIR
EEEEEECCCCEEEEECCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEE
VPNDQLSKINQRSLLEALSLGILLLLLGGGICWRAAKSMRVRDKLNQELTEQQQKLTQSN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTPVGAAQVTLSSMKNECTKLQN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AFESGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLV
HHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDMLHTSWLRMKKQSHELEIDIDANIEMNSYPGALGQSLENFVTNAITHAFEGRGNGQIK
HHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
ISAKMIEDQIVEITVSDNGIGMSAETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLG
EEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GKITVSSKLGKGSVFSLIIPVTAPETAELNLN
CEEEEECCCCCCCEEEEEEEECCCCCCEECCC
>Mature Secondary Structure 
TAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IAYHIGNIKRDALFLAKYQTLLDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNAL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHH
EKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSFYFSPLDLNVEKGEIENPIKP
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCEECCCCCCCCCCHHHH
VLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNSEL
HHHHHCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCE
TWAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIR
EEEEEECCCCEEEEECCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEE
VPNDQLSKINQRSLLEALSLGILLLLLGGGICWRAAKSMRVRDKLNQELTEQQQKLTQSN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTPVGAAQVTLSSMKNECTKLQN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AFESGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLV
HHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDMLHTSWLRMKKQSHELEIDIDANIEMNSYPGALGQSLENFVTNAITHAFEGRGNGQIK
HHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
ISAKMIEDQIVEITVSDNGIGMSAETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLG
EEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GKITVSSKLGKGSVFSLIIPVTAPETAELNLN
CEEEEECCCCCCCEEEEEEEECCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1333793 [H]