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The map label for this gene is pntB [H]

Identifier: 160874071

GI number: 160874071

Start: 1124876

End: 1126360

Strand: Reverse

Name: pntB [H]

Synonym: Sbal195_0951

Alternate gene names: 160874071

Gene position: 1126360-1124876 (Counterclockwise)

Preceding gene: 160874072

Following gene: 160874065

Centisome position: 21.06

GC content: 50.91

Gene sequence:

>1485_bases
GTGTCTCAAGGACTGGTAACAGCAGCTTACATTATTGCCGCCATTCTCTTCATCTTCAGTCTCGCGGGACTGTCGAAGCA
AGAGACGGCAAAACACGGCAATTTATTCGGTATCTTAGGTATGGCAATCGCCCTACTGGCTACCATTTTCAACCCTGATA
CTAACGGTATTGCGTGGATCTTAATCGCCATGGTGATTGGCGGCGCGATTGGTATCCGTTTAGCATTAAAAGTCGAAATG
ACTGAAATGCCTGAACTGGTTGCCATCTTGCACAGTTTTGTTGGTATGGCCGCGGTATTGGTTGGCTTTAACAGCTTTAT
CGACTTACACCCACAGGAAGTGTCGCAAGTCGTCGTAGCTGTCGGTGGCGATATTAATACGACCCTCGCCGCAGTGCACG
ATGCCCTCAGTGAAGCGGCCAAAGCCGCCAGCAAAGAACATCTCACTGGCGCCATGCTTAACATTCACTTGGTCGAAGTC
TTCCTCGGGATCTTCATCGGTGCGGTCACCTTCACAGGTTCTATCGTGGCCTTTTGTAAGTTACGCGGCGTGATTTCATC
TAAACCTTTGATGCTGCCGCATCGCCACAAGTTAAACCTAGTGGCCGTGCTCGTGTCTTTCGCCCTGTTGGTGTACTTCG
TCCAAACTGGCGGCACTATGCCGGCACTGCTGTTGATGACCTTGATTGCCTTCGCCTTTGGCTGGCATTTAGTGGCATCG
ATTGGCGGCGCAGATATGCCAGTGGTGGTGTCTATGCTGAACTCCTACTCAGGTTGGGCAGCAGCGGCAGCGGGCTTTAT
GTTGTCGAACGACCTCTTGATTGTCGTTGGCGCATTAGTGGGTTCATCAGGTGCAATTCTGTCTTACATCATGTGTAAGG
CGATGAATCGCTCGTTTATTTCTGTAATCGCAGGTGGCTTTGGCACAGATGGTGTGGCCTCGACTGCCGATGAAGAAATG
GGCGAATACCGTGAAACCAACGCTGAAGATGTGGCGGATATGCTGAAAAATGCCACCTCTGTCATCATCACCCCAGGTTA
CGGAATGGCAGTGGCACAGGCGCAATATCCTGTCGCTGAAATCACCAAAAGACTGCGCGATCTTGGCGTGAAAGTCCGTT
TCGGCATCCACCCAGTTGCAGGCCGTTTACCCGGCCACATGAACGTACTGCTAGCGGAAGCGAAAGTCCCCTACGATATC
GTGCTTGAAATGGACGAAATCAACGACGACTTTAACGACACTGACGTAGTACTAGTCATTGGTGCGAACGACACGGTTAA
CCCTGCGGCAATGGAAGATCCAGGTAGCCCAATCGCAGGCATGCCAGTGCTCGAAGTGTGGAAAGCGCAAAACGTTATCG
GCTTTAAGCGCTCGATGAACACTGGTTATGCCGGCGTGCAAAACCCACTGTTCTTTAAAGATAATACCCAAATGCTGTTT
GGGGATGCGAAGGCCAGTGTCGAAGCGATTTTAAAAGCGCTTTGA

Upstream 100 bases:

>100_bases
CGTTTATCGCCGTGCTGATCGCCAGTATTAACATCTTCGGTGGCTTTACCGTCACTCAGCGCATGCTGAAGATGTTCCGT
AAGGATTAAGGGGGTTTAAC

Downstream 100 bases:

>100_bases
GCCTGATGTAACTTCAACAGAGTGTAAATCGCTTAGGCGAAACACACTGTTTCAATGATAAAAAGGGAGCCGCTGGCTCC
CTTCTTATATCGTATCTCGC

Product: pyridine nucleotide transhydrogenase

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSQGLVTAAYIIAAILFIFSLAGLSKQETAKHGNLFGILGMAIALLATIFNPDTNGIAWILIAMVIGGAIGIRLALKVEM
TEMPELVAILHSFVGMAAVLVGFNSFIDLHPQEVSQVVVAVGGDINTTLAAVHDALSEAAKAASKEHLTGAMLNIHLVEV
FLGIFIGAVTFTGSIVAFCKLRGVISSKPLMLPHRHKLNLVAVLVSFALLVYFVQTGGTMPALLLMTLIAFAFGWHLVAS
IGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVVGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGVASTADEEM
GEYRETNAEDVADMLKNATSVIITPGYGMAVAQAQYPVAEITKRLRDLGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDI
VLEMDEINDDFNDTDVVLVIGANDTVNPAAMEDPGSPIAGMPVLEVWKAQNVIGFKRSMNTGYAGVQNPLFFKDNTQMLF
GDAKASVEAILKAL

Sequences:

>Translated_494_residues
MSQGLVTAAYIIAAILFIFSLAGLSKQETAKHGNLFGILGMAIALLATIFNPDTNGIAWILIAMVIGGAIGIRLALKVEM
TEMPELVAILHSFVGMAAVLVGFNSFIDLHPQEVSQVVVAVGGDINTTLAAVHDALSEAAKAASKEHLTGAMLNIHLVEV
FLGIFIGAVTFTGSIVAFCKLRGVISSKPLMLPHRHKLNLVAVLVSFALLVYFVQTGGTMPALLLMTLIAFAFGWHLVAS
IGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVVGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGVASTADEEM
GEYRETNAEDVADMLKNATSVIITPGYGMAVAQAQYPVAEITKRLRDLGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDI
VLEMDEINDDFNDTDVVLVIGANDTVNPAAMEDPGSPIAGMPVLEVWKAQNVIGFKRSMNTGYAGVQNPLFFKDNTQMLF
GDAKASVEAILKAL
>Mature_493_residues
SQGLVTAAYIIAAILFIFSLAGLSKQETAKHGNLFGILGMAIALLATIFNPDTNGIAWILIAMVIGGAIGIRLALKVEMT
EMPELVAILHSFVGMAAVLVGFNSFIDLHPQEVSQVVVAVGGDINTTLAAVHDALSEAAKAASKEHLTGAMLNIHLVEVF
LGIFIGAVTFTGSIVAFCKLRGVISSKPLMLPHRHKLNLVAVLVSFALLVYFVQTGGTMPALLLMTLIAFAFGWHLVASI
GGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVVGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGVASTADEEMG
EYRETNAEDVADMLKNATSVIITPGYGMAVAQAQYPVAEITKRLRDLGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDIV
LEMDEINDDFNDTDVVLVIGANDTVNPAAMEDPGSPIAGMPVLEVWKAQNVIGFKRSMNTGYAGVQNPLFFKDNTQMLFG
DAKASVEAILKAL

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=489, Percent_Identity=49.2842535787321, Blast_Score=444, Evalue=1e-125,
Organism=Homo sapiens, GI122939153, Length=489, Percent_Identity=49.2842535787321, Blast_Score=444, Evalue=1e-125,
Organism=Escherichia coli, GI1787886, Length=497, Percent_Identity=76.4587525150905, Blast_Score=734, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17550456, Length=490, Percent_Identity=47.5510204081633, Blast_Score=414, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 52099; Mature: 51968

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHC
>Mature Secondary Structure 
SQGLVTAAYIIAAILFIFSLAGLSKQETAKHGNLFGILGMAIALLATIFNPDTNGIAWI
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHH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CCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]