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The map label for this gene is ugd [H]

Identifier: 160873714

GI number: 160873714

Start: 692871

End: 694040

Strand: Direct

Name: ugd [H]

Synonym: Sbal195_0592

Alternate gene names: 160873714

Gene position: 692871-694040 (Clockwise)

Preceding gene: 160873713

Following gene: 160873717

Centisome position: 12.96

GC content: 34.53

Gene sequence:

>1170_bases
ATGAGAATAACAGTCATAGGGACTGGTTTTGTCGGGCTATCAAATGCGTTGATTTTTTCAAAAAAAAATGCGGTAATTGT
TTACGATTCAGATAAAAGCAAGGTTGATTTAATAAACAAAGGGCAACTACCACTACCCGAAGAATTTGCTGATTCTTATT
TTTTAAGAGATGGTGTAGCATTAACTGCTACTAGTTGCAAATACACTGCCTTCTCTGACGCTGACTTTGTGGTAATTTCT
GTACCAACAGACTTTGATGTTAATGCTAATAGTTTTAATACAGACCTTTTGGAAAAAATCATAACTGATGTGATATCTCA
TACTAATAAATCATCAGTTATAGTTGTAAGATCAACAGTTCCAGTTGGTTTCACTGAAAGAGTGTGCAAGAAGCTCGATA
GTAAAGATATATTATACTCACCTGATTTTTTGGGAGAATATAACACTGTATCTGATAGTATCTACCCATCTCGAATTATA
GTTGGGGAGAAATCTCACCGAGCAGAAACGTTTGCAGGGTTGATTTTTGATGCTGCTGAAAAAGAAAATATACCTGTAAT
ATATACTAGCTCTACGGAAGCAGAAGCCATAAAGTTATTCACAAACGCGTACCTTTCTATGCGTGTAGCGTATTTCAATG
AACTAGATAGTTTCGCTTATGTAAGTGGGTTATCCTCACTTCAGATTATTACTGGTGTATGCTCTGATCCAAGAGTTGGT
CATGGTTATAATAATCCATCATTCGGCTGTGGAGCAGGCGTAGAAAACAAAGATACAAAGCAGCTACGTTCAAGTTGTTC
AGATAACCCAAATGATTTAATTAGAGCTATTGTTAACTCTAATGAAACAAGAATAGATTTTATCGCTGAGTCTATCATTA
AATTAAAACCTTATACAGTAGGATTTTATGGATTAGCAGTTAATTCTGAGGCGGGTAACTTTCTTCAGTCGTCTACTGTA
TGTGTCATGAATATAATTAAATCTAAAGGTGTCGAAGTTATAATTTATGATCCAAAAATAGATGGCGAAGAATATCTTGA
CGCGCAACTGATACGTAATTTAGATCTTTTTAAGATGCTTAGTGATGTCATAGTAACGCAAAGAATGGTTCCAGAGCTTA
AAAATGTATGTGAAAAAGTATACACTAGAGATATTTTAGGTACGAATTAA

Upstream 100 bases:

>100_bases
CTTTTTTACTTTAAAGCTGGTTAGATTTTCCAGTATGGTGAGCATACATTGTGGTTTACAGAAGTTGCCCACTTAAATTA
AAACTGTGTTGGATATTTTT

Downstream 100 bases:

>100_bases
TCATAAATTGAGATGTTCAAAGTTGCCATGCATTGTTGATGCTTTATAAAAAACAATTCGACATGAACAGTTATTCTGAA
AAGATTAATTCGTATTGCAA

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MRITVIGTGFVGLSNALIFSKKNAVIVYDSDKSKVDLINKGQLPLPEEFADSYFLRDGVALTATSCKYTAFSDADFVVIS
VPTDFDVNANSFNTDLLEKIITDVISHTNKSSVIVVRSTVPVGFTERVCKKLDSKDILYSPDFLGEYNTVSDSIYPSRII
VGEKSHRAETFAGLIFDAAEKENIPVIYTSSTEAEAIKLFTNAYLSMRVAYFNELDSFAYVSGLSSLQIITGVCSDPRVG
HGYNNPSFGCGAGVENKDTKQLRSSCSDNPNDLIRAIVNSNETRIDFIAESIIKLKPYTVGFYGLAVNSEAGNFLQSSTV
CVMNIIKSKGVEVIIYDPKIDGEEYLDAQLIRNLDLFKMLSDVIVTQRMVPELKNVCEKVYTRDILGTN

Sequences:

>Translated_389_residues
MRITVIGTGFVGLSNALIFSKKNAVIVYDSDKSKVDLINKGQLPLPEEFADSYFLRDGVALTATSCKYTAFSDADFVVIS
VPTDFDVNANSFNTDLLEKIITDVISHTNKSSVIVVRSTVPVGFTERVCKKLDSKDILYSPDFLGEYNTVSDSIYPSRII
VGEKSHRAETFAGLIFDAAEKENIPVIYTSSTEAEAIKLFTNAYLSMRVAYFNELDSFAYVSGLSSLQIITGVCSDPRVG
HGYNNPSFGCGAGVENKDTKQLRSSCSDNPNDLIRAIVNSNETRIDFIAESIIKLKPYTVGFYGLAVNSEAGNFLQSSTV
CVMNIIKSKGVEVIIYDPKIDGEEYLDAQLIRNLDLFKMLSDVIVTQRMVPELKNVCEKVYTRDILGTN
>Mature_389_residues
MRITVIGTGFVGLSNALIFSKKNAVIVYDSDKSKVDLINKGQLPLPEEFADSYFLRDGVALTATSCKYTAFSDADFVVIS
VPTDFDVNANSFNTDLLEKIITDVISHTNKSSVIVVRSTVPVGFTERVCKKLDSKDILYSPDFLGEYNTVSDSIYPSRII
VGEKSHRAETFAGLIFDAAEKENIPVIYTSSTEAEAIKLFTNAYLSMRVAYFNELDSFAYVSGLSSLQIITGVCSDPRVG
HGYNNPSFGCGAGVENKDTKQLRSSCSDNPNDLIRAIVNSNETRIDFIAESIIKLKPYTVGFYGLAVNSEAGNFLQSSTV
CVMNIIKSKGVEVIIYDPKIDGEEYLDAQLIRNLDLFKMLSDVIVTQRMVPELKNVCEKVYTRDILGTN

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=381, Percent_Identity=23.0971128608924, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI296040438, Length=269, Percent_Identity=22.3048327137546, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI296040443, Length=222, Percent_Identity=22.972972972973, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1788340, Length=389, Percent_Identity=48.8431876606684, Blast_Score=380, Evalue=1e-106,
Organism=Escherichia coli, GI48994968, Length=263, Percent_Identity=26.9961977186312, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560350, Length=376, Percent_Identity=23.936170212766, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI17136908, Length=380, Percent_Identity=25.5263157894737, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 42864; Mature: 42864

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITVIGTGFVGLSNALIFSKKNAVIVYDSDKSKVDLINKGQLPLPEEFADSYFLRDGVA
CEEEEEECCCHHHCCEEEEECCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCE
LTATSCKYTAFSDADFVVISVPTDFDVNANSFNTDLLEKIITDVISHTNKSSVIVVRSTV
EEECCCEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
PVGFTERVCKKLDSKDILYSPDFLGEYNTVSDSIYPSRIIVGEKSHRAETFAGLIFDAAE
CCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHEECCC
KENIPVIYTSSTEAEAIKLFTNAYLSMRVAYFNELDSFAYVSGLSSLQIITGVCSDPRVG
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCCC
HGYNNPSFGCGAGVENKDTKQLRSSCSDNPNDLIRAIVNSNETRIDFIAESIIKLKPYTV
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
GFYGLAVNSEAGNFLQSSTVCVMNIIKSKGVEVIIYDPKIDGEEYLDAQLIRNLDLFKML
EEEEEEEECCCCCHHHHCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHH
SDVIVTQRMVPELKNVCEKVYTRDILGTN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRITVIGTGFVGLSNALIFSKKNAVIVYDSDKSKVDLINKGQLPLPEEFADSYFLRDGVA
CEEEEEECCCHHHCCEEEEECCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCE
LTATSCKYTAFSDADFVVISVPTDFDVNANSFNTDLLEKIITDVISHTNKSSVIVVRSTV
EEECCCEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
PVGFTERVCKKLDSKDILYSPDFLGEYNTVSDSIYPSRIIVGEKSHRAETFAGLIFDAAE
CCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHEECCC
KENIPVIYTSSTEAEAIKLFTNAYLSMRVAYFNELDSFAYVSGLSSLQIITGVCSDPRVG
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCCC
HGYNNPSFGCGAGVENKDTKQLRSSCSDNPNDLIRAIVNSNETRIDFIAESIIKLKPYTV
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
GFYGLAVNSEAGNFLQSSTVCVMNIIKSKGVEVIIYDPKIDGEEYLDAQLIRNLDLFKML
EEEEEEEECCCCCHHHHCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHH
SDVIVTQRMVPELKNVCEKVYTRDILGTN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]