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The map label for this gene is udp [H]

Identifier: 160873667

GI number: 160873667

Start: 631564

End: 632298

Strand: Direct

Name: udp [H]

Synonym: Sbal195_0545

Alternate gene names: 160873667

Gene position: 631564-632298 (Clockwise)

Preceding gene: 160873666

Following gene: 160873668

Centisome position: 11.81

GC content: 46.12

Gene sequence:

>735_bases
ATGAACCTACAACCACACATTGCTGTCAGTGCTGACGATATAGCTTCTAGAGTGATTGTGTGTGGTGATCCTGCTCGTGC
AGCGCGTATCGCGGGTTGGTGTGAAAACGGCAAACAAGTTGCCAGTAATCGTGAGTTTCAGTTATTTAATGCACGATTTA
ACGGTATAGATGTCACGATTTGCAGTACAGGTATAGGCGCTGCTTCAATGCTGATTGCATTAGAGGAGCTTAAACAGTGC
GGAGTTACTACCATCATTCGTGTTGGGTCTGCAGGAGCGTTGCAACACAATATTGGCCTAGGAGAATTGATTATTGCCGA
AGGGGCTGTTCGTGACGAAGGGGGCTCCTTGAGCTACCTTCCTGCATCCTACCCTGCTGTAGCCGATCATGCCTTAGTTG
CGGGCTTACTTAGTGCAGCTAAGCAACTTCAAAGTAAATATTACTTAGGCTTAGTGCGTTCCCATGACAGTTTTTATACC
GACCAAGAGACGGAAATTTGTGAGTTTTGGCACCAGCGTGGTGTACTTGCTGCTGACATGGAAACCTCTGCACTGTTAAC
GGTCGGGCGTTTCCGTGGTTTGCAGGTTGCATCCATTCTTAATAACGTTGTTCTATTTGAGCAGGAAGTTAAAGAAGGTA
TTGGTCAGTTTAAACAAGTTAACGGCAGTATGATTGAGGGGGAAAAGCGTTCAGCAATGATTGCGTTGCAAGCGCTAACA
AGCCATAGGAGTTAA

Upstream 100 bases:

>100_bases
TCGAATACGCAATTCTGCTATTCATCGCATTGAATGGCACGCGAGTATGGATGGCAACTGCAAAGTCTAACCAAGCCAAA
TCCTCAAAGCAGGCGGTGCT

Downstream 100 bases:

>100_bases
CTTCAACAATCGTAGTCAATGGCGCGCTACTCTATCGATGGAATCTATTTTATGTGCCTCGAATGAGTGGACGCGTTATT
GCTGCGGCATGTAAAGTGAT

Product: purine phosphorylase family 1

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MNLQPHIAVSADDIASRVIVCGDPARAARIAGWCENGKQVASNREFQLFNARFNGIDVTICSTGIGAASMLIALEELKQC
GVTTIIRVGSAGALQHNIGLGELIIAEGAVRDEGGSLSYLPASYPAVADHALVAGLLSAAKQLQSKYYLGLVRSHDSFYT
DQETEICEFWHQRGVLAADMETSALLTVGRFRGLQVASILNNVVLFEQEVKEGIGQFKQVNGSMIEGEKRSAMIALQALT
SHRS

Sequences:

>Translated_244_residues
MNLQPHIAVSADDIASRVIVCGDPARAARIAGWCENGKQVASNREFQLFNARFNGIDVTICSTGIGAASMLIALEELKQC
GVTTIIRVGSAGALQHNIGLGELIIAEGAVRDEGGSLSYLPASYPAVADHALVAGLLSAAKQLQSKYYLGLVRSHDSFYT
DQETEICEFWHQRGVLAADMETSALLTVGRFRGLQVASILNNVVLFEQEVKEGIGQFKQVNGSMIEGEKRSAMIALQALT
SHRS
>Mature_244_residues
MNLQPHIAVSADDIASRVIVCGDPARAARIAGWCENGKQVASNREFQLFNARFNGIDVTICSTGIGAASMLIALEELKQC
GVTTIIRVGSAGALQHNIGLGELIIAEGAVRDEGGSLSYLPASYPAVADHALVAGLLSAAKQLQSKYYLGLVRSHDSFYT
DQETEICEFWHQRGVLAADMETSALLTVGRFRGLQVASILNNVVLFEQEVKEGIGQFKQVNGSMIEGEKRSAMIALQALT
SHRS

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=236, Percent_Identity=33.0508474576271, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790844, Length=210, Percent_Identity=29.5238095238095, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 26163; Mature: 26163

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQPHIAVSADDIASRVIVCGDPARAARIAGWCENGKQVASNREFQLFNARFNGIDVTI
CCCCCCEEECHHHHHCEEEEECCCHHHHHHHHHHCCCHHHHCCCCEEEEEEEECCEEEEE
CSTGIGAASMLIALEELKQCGVTTIIRVGSAGALQHNIGLGELIIAEGAVRDEGGSLSYL
ECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCEEEEECCCEECCCCCEEEC
PASYPAVADHALVAGLLSAAKQLQSKYYLGLVRSHDSFYTDQETEICEFWHQRGVLAADM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHCCCEEECC
ETSALLTVGRFRGLQVASILNNVVLFEQEVKEGIGQFKQVNGSMIEGEKRSAMIALQALT
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHH
SHRS
CCCC
>Mature Secondary Structure
MNLQPHIAVSADDIASRVIVCGDPARAARIAGWCENGKQVASNREFQLFNARFNGIDVTI
CCCCCCEEECHHHHHCEEEEECCCHHHHHHHHHHCCCHHHHCCCCEEEEEEEECCEEEEE
CSTGIGAASMLIALEELKQCGVTTIIRVGSAGALQHNIGLGELIIAEGAVRDEGGSLSYL
ECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCEEEEECCCEECCCCCEEEC
PASYPAVADHALVAGLLSAAKQLQSKYYLGLVRSHDSFYTDQETEICEFWHQRGVLAADM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHCCCEEECC
ETSALLTVGRFRGLQVASILNNVVLFEQEVKEGIGQFKQVNGSMIEGEKRSAMIALQALT
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHH
SHRS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]