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The map label for this gene is puuP [H]

Identifier: 160873652

GI number: 160873652

Start: 610496

End: 611827

Strand: Direct

Name: puuP [H]

Synonym: Sbal195_0530

Alternate gene names: 160873652

Gene position: 610496-611827 (Clockwise)

Preceding gene: 160873651

Following gene: 160873655

Centisome position: 11.42

GC content: 47.52

Gene sequence:

>1332_bases
ATGAGTCAACACAAACCGGGTTTGAAGCAGACCCTCAATTTATGGCAAGTGGTAGTGATGGGGCTCGCCTATCTCACACC
TATGGCTGTTTTTGACACCTTTGGTATTGTTTCTGAGATTACCTCTGGCCATGTGGCTACGTCCTATCTATTCGCACTGG
CGGGAATTTTGTTTACCGCATTCAGTTATGGCCATTTAGTGCGTAAATATCCCTATGCGGGGTCAGCCTACACTTACGCC
CAGAAAACTTTTAGTCCGAATGTCGGTTTTATGGTGGGCTGGTCGTCGCTACTTGATTATATGTTTATGCCAATGATCAA
CATGTTGCTGGCAAAAATCTATTTAACTGCCATGTTCCCCACTGTCGAACCTTGGATCTTCATTTTCGCACTCGTGACCA
TAATGACCCTGCTCAATCTTAAAGGGATTGATCTGGTGGCTAACTTTAATGGGGTGATAGTGTTTGTGCAAATCGCCATT
ATCCTCGTGTTTATTGCATTAATGGCCTATAGCATTTCCCTTGGTGAAGGCGAAGGTGCGATTGCAAGCGTGCGACCATT
TTATGCCGAGAATATGGCGATTGTGCCGTTATTTACTGGCGCCACTATTCTGTGTTTTTCCTTCCTCGGCTTTGACGGTT
TGAGCTCGCTGACCGAAGAAACGAAGGATGCGCAGCGTGTTATTCCGCGCGCGATTGTGTTGACCGCCTTGATTGGTGGG
GTGATTTTTGTCGGCGTGTCTTATTTTCTTCAGCTTTATTTCCCCGATATTTCCCGCTTCCAGGAGCTTGATGCTGTATT
GCCCGAAATCGCACTCTATGTTGGAGGAAACTTATTCCAGTCCATCGTATTAGTGGCGACTACAGTGGCGGTGTTGGCAT
CCGGTATGGCTGCCCACGCTGGCGTTGCACGGATTTTGTATGTGATGGGGCGGGACAACATGCTGCCACGTAAAGGGTTT
GCTTATATCCACCCTAAGTGGCGCACCCCTGCATTTAATGTTTTGTTGGTGGGGGCATTGGCGCTGTCTGCCGTATCATT
TGATTTGGAAATGGCCTTAGCCTTAGTTAACTTTGGCGCCTTAGTGGCGTTCACCTTCGTGAACTTAGCCGTCATTGTGC
AGTTTTATGTGAGGGATCGACGTAATCAATCCTTTAAGGATCACCTGCAATACTTAGTCTTGCCCCTGTGTGGCGCCGGC
ACTATTGGGGTACTTTGGGCGAACTTAGAGCCACAGTCTTTAGAGTTGGGATTGATTTGGGCTGCCGTGGGAGCTTTATA
TTTAACCCTGCGTAGCATACGTTTACGCCGAATTGTAGAGTTACACAATTAG

Upstream 100 bases:

>100_bases
AGTTAGCCATTAAGCCTAAAGTGCTGATGGTGAGTCACATGCCAAAACCAATTGCAGATGCATGGTTAGCTGTTCACCCC
TGTGCAATGGGGGCGTGCTC

Downstream 100 bases:

>100_bases
TTGCAGCATAGGATTGTAGAGTCGCAGTTATTGCTTACAACTGACAAGGGTTTGATTGAGCTGTCATAGTTTTCTAATAA
AACGTCCAACTGAAAAGACC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSQHKPGLKQTLNLWQVVVMGLAYLTPMAVFDTFGIVSEITSGHVATSYLFALAGILFTAFSYGHLVRKYPYAGSAYTYA
QKTFSPNVGFMVGWSSLLDYMFMPMINMLLAKIYLTAMFPTVEPWIFIFALVTIMTLLNLKGIDLVANFNGVIVFVQIAI
ILVFIALMAYSISLGEGEGAIASVRPFYAENMAIVPLFTGATILCFSFLGFDGLSSLTEETKDAQRVIPRAIVLTALIGG
VIFVGVSYFLQLYFPDISRFQELDAVLPEIALYVGGNLFQSIVLVATTVAVLASGMAAHAGVARILYVMGRDNMLPRKGF
AYIHPKWRTPAFNVLLVGALALSAVSFDLEMALALVNFGALVAFTFVNLAVIVQFYVRDRRNQSFKDHLQYLVLPLCGAG
TIGVLWANLEPQSLELGLIWAAVGALYLTLRSIRLRRIVELHN

Sequences:

>Translated_443_residues
MSQHKPGLKQTLNLWQVVVMGLAYLTPMAVFDTFGIVSEITSGHVATSYLFALAGILFTAFSYGHLVRKYPYAGSAYTYA
QKTFSPNVGFMVGWSSLLDYMFMPMINMLLAKIYLTAMFPTVEPWIFIFALVTIMTLLNLKGIDLVANFNGVIVFVQIAI
ILVFIALMAYSISLGEGEGAIASVRPFYAENMAIVPLFTGATILCFSFLGFDGLSSLTEETKDAQRVIPRAIVLTALIGG
VIFVGVSYFLQLYFPDISRFQELDAVLPEIALYVGGNLFQSIVLVATTVAVLASGMAAHAGVARILYVMGRDNMLPRKGF
AYIHPKWRTPAFNVLLVGALALSAVSFDLEMALALVNFGALVAFTFVNLAVIVQFYVRDRRNQSFKDHLQYLVLPLCGAG
TIGVLWANLEPQSLELGLIWAAVGALYLTLRSIRLRRIVELHN
>Mature_442_residues
SQHKPGLKQTLNLWQVVVMGLAYLTPMAVFDTFGIVSEITSGHVATSYLFALAGILFTAFSYGHLVRKYPYAGSAYTYAQ
KTFSPNVGFMVGWSSLLDYMFMPMINMLLAKIYLTAMFPTVEPWIFIFALVTIMTLLNLKGIDLVANFNGVIVFVQIAII
LVFIALMAYSISLGEGEGAIASVRPFYAENMAIVPLFTGATILCFSFLGFDGLSSLTEETKDAQRVIPRAIVLTALIGGV
IFVGVSYFLQLYFPDISRFQELDAVLPEIALYVGGNLFQSIVLVATTVAVLASGMAAHAGVARILYVMGRDNMLPRKGFA
YIHPKWRTPAFNVLLVGALALSAVSFDLEMALALVNFGALVAFTFVNLAVIVQFYVRDRRNQSFKDHLQYLVLPLCGAGT
IGVLWANLEPQSLELGLIWAAVGALYLTLRSIRLRRIVELHN

Specific function: Imports putrescine [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=426, Percent_Identity=24.6478873239437, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI258614005, Length=416, Percent_Identity=25.4807692307692, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI258614003, Length=410, Percent_Identity=25.609756097561, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI114326544, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI114326550, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI258645169, Length=410, Percent_Identity=25.3658536585366, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI186910308, Length=341, Percent_Identity=23.4604105571848, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI186910306, Length=341, Percent_Identity=23.4604105571848, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI186910304, Length=341, Percent_Identity=23.4604105571848, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081869, Length=434, Percent_Identity=63.1336405529954, Blast_Score=570, Evalue=1e-164,
Organism=Escherichia coli, GI87082023, Length=436, Percent_Identity=62.6146788990826, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI87082250, Length=348, Percent_Identity=22.7011494252874, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17532491, Length=420, Percent_Identity=24.2857142857143, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17533459, Length=422, Percent_Identity=25.1184834123223, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531343, Length=402, Percent_Identity=24.8756218905473, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24668806, Length=413, Percent_Identity=25.6658595641646, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI21356285, Length=413, Percent_Identity=25.6658595641646, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24668802, Length=413, Percent_Identity=25.6658595641646, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI221512776, Length=407, Percent_Identity=22.8501228501229, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24666159, Length=407, Percent_Identity=22.8501228501229, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667468, Length=400, Percent_Identity=24, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281366235, Length=403, Percent_Identity=25.5583126550869, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007820, Length=403, Percent_Identity=25.5583126550869, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007818, Length=403, Percent_Identity=25.5583126550869, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI85725152, Length=403, Percent_Identity=25.5583126550869, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161077963, Length=402, Percent_Identity=22.8855721393035, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48673; Mature: 48542

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQHKPGLKQTLNLWQVVVMGLAYLTPMAVFDTFGIVSEITSGHVATSYLFALAGILFTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FSYGHLVRKYPYAGSAYTYAQKTFSPNVGFMVGWSSLLDYMFMPMINMLLAKIYLTAMFP
HHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
TVEPWIFIFALVTIMTLLNLKGIDLVANFNGVIVFVQIAIILVFIALMAYSISLGEGEGA
CHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IASVRPFYAENMAIVPLFTGATILCFSFLGFDGLSSLTEETKDAQRVIPRAIVLTALIGG
EEECCCHHHCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIFVGVSYFLQLYFPDISRFQELDAVLPEIALYVGGNLFQSIVLVATTVAVLASGMAAHA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
GVARILYVMGRDNMLPRKGFAYIHPKWRTPAFNVLLVGALALSAVSFDLEMALALVNFGA
HHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAFTFVNLAVIVQFYVRDRRNQSFKDHLQYLVLPLCGAGTIGVLWANLEPQSLELGLIW
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
AAVGALYLTLRSIRLRRIVELHN
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQHKPGLKQTLNLWQVVVMGLAYLTPMAVFDTFGIVSEITSGHVATSYLFALAGILFTA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FSYGHLVRKYPYAGSAYTYAQKTFSPNVGFMVGWSSLLDYMFMPMINMLLAKIYLTAMFP
HHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
TVEPWIFIFALVTIMTLLNLKGIDLVANFNGVIVFVQIAIILVFIALMAYSISLGEGEGA
CHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IASVRPFYAENMAIVPLFTGATILCFSFLGFDGLSSLTEETKDAQRVIPRAIVLTALIGG
EEECCCHHHCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIFVGVSYFLQLYFPDISRFQELDAVLPEIALYVGGNLFQSIVLVATTVAVLASGMAAHA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
GVARILYVMGRDNMLPRKGFAYIHPKWRTPAFNVLLVGALALSAVSFDLEMALALVNFGA
HHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAFTFVNLAVIVQFYVRDRRNQSFKDHLQYLVLPLCGAGTIGVLWANLEPQSLELGLIW
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
AAVGALYLTLRSIRLRRIVELHN
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]