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The map label for this gene is ubiB [H]

Identifier: 160873554

GI number: 160873554

Start: 494224

End: 495873

Strand: Reverse

Name: ubiB [H]

Synonym: Sbal195_0429

Alternate gene names: 160873554

Gene position: 495873-494224 (Counterclockwise)

Preceding gene: 160873555

Following gene: 160873553

Centisome position: 9.27

GC content: 46.36

Gene sequence:

>1650_bases
ATGACCCTTGCCAGTATCCGCCGCGGTTACCATGTCATCAAGACCTTGCTTCAGTACGGGTTAGATGACGTATTGCCGCC
AAAGATGACACCTTGGTACTTTAAACTCGCCCGTAATAGCCTGTTCTGGATCCGCAATAAGCATAAAAATAAGCCCGGTG
GCGAACGCTTAAAATTGGCGATGCAGGAACTGGGCCCCGTTTATATCAAGCTTGGGCAAATGCTCTCGACCCGCCGCGAT
TTACTCAGCGATGAATGGGCCAGTGAATTAGCCATGCTACAGGACAAGGTGCCGCCCTTTGATGGTGCGCTCGCCCGCCA
AGCGATTGAAGCTGAACTAAAAGCGCCGATTGAATCCCTATTCGATGACTTTAATGAAACCCCGCTGGCATCAGCCTCTA
TTTCTCAAGTGCATACAGCGACCTTAAAATCTAACGGCAAAGACGTCGTACTTAAGGTGCTACGGCCGAATGTAGAAACC
AAGATTCAGGCCGATCTGCAGTTGATGTCGCAAACCGCCAAGTTGATTGAATACCTCCTCGGTGAAGGCAACCGCCTGCG
CCCTGCCGAAGTGATCGAAGATTACCGAGTGACCATTTTAGGTGAGTTAAACCTTAAGCTCGAAGCATTAAACGCAGTCA
AGTTACGCAACAACTTCCTCGACTCAGATGCGCTCTATGTGCCTTATGTGTATGAAGAATTTTGCTATCCGCGCTTAATG
GTGATGGAACGAATTTACGGTATTTCGGTCTCGGATATTGCCGCCCTTAAAGCGCAAGGCACCAACTTTAAGTTATTAGC
TGAGCGCGGAGTAGAGCTGTTTTTCACCCAAGTGTTCCGCGATAACTTTTTCCATGCCGACATGCATCCGGGCAATATCT
TTATTTCCCGCGATCATCCAGAGAACCCTTATTACATTGGGCTCGATTGCGGCATTATGGGCACACTCAGCGAAGTCGAT
AAACGCTATCTCGCCGAGAATTTCCTCGCCTTCTTTAATCGCGATTATCACCGAATTGCCCAGCTCTATATTGAATCAGG
TTGGGTATCTGAAAAAACCGATCTACAGGCCTTTGAACAGGCCATCAAAGTAGTGTGCGAACCTATGTTCAACAAGCCAC
TCGACGAGATTTCCTTTGGTCATGTGTTACTGGAATTATTCCGCACTGCACGCCACTTCGATATCGTGGTACAACCGCAG
TTGGTATTGCTGGAAAAGACCTTACTTTATATCGAAGGCTTAGGTCGTCAGCTGTATCCGCAGTTGGATTTATGGCAAAC
AGCTAAACCGTTTTTAGAGCAGTGGATGGCCGACCAAGTAGGTCCTAAGGCTATGTTTAAAAAGGTATCCACAAAACTGC
CATATTGGGCTGATAAACTACCAGAATTCCCTGAACTGATTTACGATAACCTTAAGTTAGGCAGGAAATTGCTGAGTTCT
CAGCAACAAATGCTAGATAAGTATTTGAAATACCAGCAGCAGGCTCACAAGAGTAACTACTTGCTTATCACTTCTGCAGT
TTTATTGATCTGTGGCACGTTATTGATCAATAGAGACGCTACACTATGGACCCCTTATGTTTGTCTAGTTTCAGGCATTA
TATTGTGGTTTGTCGGATGGCGATCTAGGCCAAAGAATCGCAAATTTTAG

Upstream 100 bases:

>100_bases
CAATTGAGTTACTTCATTTTCGCGATCAAATGGATGATTTAGTTGCCGATACCCGCGCGATTGAACAACGGATTGCCCAA
TTAAGAGATCAAATTAAGCC

Downstream 100 bases:

>100_bases
CTAGCACTAATAAATCATAGGTTCATAATAGAACCGATATCAATTAAGAGGATACCTTCATGGGTGGTATTAGTATTTGG
CAACTTCTTATCGTTGCATT

Product: 2-polyprenylphenol 6-hydroxylase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLAMQELGPVYIKLGQMLSTRRD
LLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESLFDDFNETPLASASISQVHTATLKSNGKDVVLKVLRPNVET
KIQADLQLMSQTAKLIEYLLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLM
VMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVD
KRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQ
LVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSS
QQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGWRSRPKNRKF

Sequences:

>Translated_549_residues
MTLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLAMQELGPVYIKLGQMLSTRRD
LLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESLFDDFNETPLASASISQVHTATLKSNGKDVVLKVLRPNVET
KIQADLQLMSQTAKLIEYLLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLM
VMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVD
KRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQ
LVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSS
QQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGWRSRPKNRKF
>Mature_548_residues
TLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLAMQELGPVYIKLGQMLSTRRDL
LSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESLFDDFNETPLASASISQVHTATLKSNGKDVVLKVLRPNVETK
IQADLQLMSQTAKLIEYLLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLMV
MERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVDK
RYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQL
VLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSSQ
QQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGWRSRPKNRKF

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=254, Percent_Identity=28.740157480315, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI41393593, Length=271, Percent_Identity=26.9372693726937, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI217035081, Length=209, Percent_Identity=27.7511961722488, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI34147522, Length=220, Percent_Identity=27.7272727272727, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI2367309, Length=547, Percent_Identity=58.3180987202925, Blast_Score=653, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559152, Length=283, Percent_Identity=25.7950530035336, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17555620, Length=469, Percent_Identity=21.7484008528785, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6325148, Length=469, Percent_Identity=26.4392324093817, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323282, Length=305, Percent_Identity=28.1967213114754, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=212, Percent_Identity=28.7735849056604, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI22024280, Length=253, Percent_Identity=30.0395256916996, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24662575, Length=249, Percent_Identity=28.1124497991968, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 63365; Mature: 63233

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLA
CCHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHH
MQELGPVYIKLGQMLSTRRDLLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FDDFNETPLASASISQVHTATLKSNGKDVVLKVLRPNVETKIQADLQLMSQTAKLIEYLL
HHCCCCCCCCCHHHHHHHHHHHHCCCHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLM
CCCCCCCHHHHHCCCEEEEEEECCEEEHHHHHHHHHHCCCCCCCEECCHHHHHHCCHHHH
VMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHP
HHHHHHCCCHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHHCCCEECCCCCCEEEEECCCC
ENPYYIGLDCGIMGTLSEVDKRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQ
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHH
AIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQLVLLEKTLLYIEGLGRQLYP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCHHHCC
QLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
QQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGW
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RSRPKNRKF
CCCCCCCCC
>Mature Secondary Structure 
TLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLA
CHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHH
MQELGPVYIKLGQMLSTRRDLLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FDDFNETPLASASISQVHTATLKSNGKDVVLKVLRPNVETKIQADLQLMSQTAKLIEYLL
HHCCCCCCCCCHHHHHHHHHHHHCCCHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLM
CCCCCCCHHHHHCCCEEEEEEECCEEEHHHHHHHHHHCCCCCCCEECCHHHHHHCCHHHH
VMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHP
HHHHHHCCCHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHHCCCEECCCCCCEEEEECCCC
ENPYYIGLDCGIMGTLSEVDKRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQ
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHH
AIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQLVLLEKTLLYIEGLGRQLYP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCHHHCC
QLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
QQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGW
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RSRPKNRKF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA