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The map label for this gene is yrbG [H]

Identifier: 160873480

GI number: 160873480

Start: 402287

End: 403231

Strand: Reverse

Name: yrbG [H]

Synonym: Sbal195_0355

Alternate gene names: 160873480

Gene position: 403231-402287 (Counterclockwise)

Preceding gene: 160873481

Following gene: 160873479

Centisome position: 7.54

GC content: 47.2

Gene sequence:

>945_bases
ATGCTCATTACACTCTCGATTATTGGCGGTTTTATTATTTTAACCTTAGGCGCCGAAGCCCTAGTGCGTGGCGCGAGTGC
TATCGCCCTACGCTTAGGTATTACGCCACTTATCATAGGCTTAACTATTGTTGCCTTTGGTACTAGCGCACCAGAACTGG
CAGTGAGTGTCAAATCTGCCCTTGCCGGAAACAGTGGTATCGCCTTAGGTAACGTTATCGGCTCCAACATTGCCAACATA
GGTTTGATCTTAGCGATCACGGCGCTAATCCGCCCTATCCAAGTGCAATCCCAAGTGGTGAAGCGCGATATCCCTTTAAT
GATCTTGGCGTCTATGCTGTTCTGGGGACTCTTATTAGACGGCGAACTCAGCCTGATTGACGGTGTGGTTTTGCTTTCAC
TACTGGTTGGATATTTAACCTTTAGCTATATCAGCTCGAAAAACAGCAAGAATGAAGAAGAGATTGAAGCGGGGCCGAAT
AACCCACTGCTTTCAGGCCTGTTCATTCTAGTCGGCATTAGCATGTTAGTTGGCGGCGGTATTCTATTTGTGAACGGCGC
GGTAGATTTAGCGAAAACCTTCGGCGTGAGTGAAGTCATTATCGGCTTAACGATCGTAGCGATTGGTACCAGTATGCCAG
AGTTAGTGACCTCAGTAATTGCGGCACTAAAAGGTCAAAGCGATATCGCTATCGGCAACGTTGTGGGTTCTAACTTGTTC
AATATTTTGGGCATTTTAGGTGTTACTGCCATAGTGCATCCAGTGTCGTCACTCGGTTTCCAACCCTTCGACTTTATGGT
GATGTTAGCCTTAGCCATAGTGATACTGCCTTTTGCATGGACGGGATTACGCATCGGCCGCCGCGAAGGTTCTGTGCTGC
TACTGACCTATTTAGGTTATATGGGTTACCTGATTAACCAAGCGAGCGCTCAAGCTTTGGTATAA

Upstream 100 bases:

>100_bases
CTGTCAAATTTCGATAAAACCACGTATCATGTGCGCCTGTCGGCTAAGGGATGATTCCCTTGTACTTTCCCATTAAATAT
AGGTTTAACAAAGTCCCGTG

Downstream 100 bases:

>100_bases
TACTCAGCGGTAATATCCACTTAGAACACCGGAGCCTCTCCGGTGTTTTGCTATCTGAGTTTCGAACTTTTTAAAAAAGA
CAAGTTTAACACCCTTCAAC

Product: CaCA family Na(+)/Ca(+) antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLITLSIIGGFIILTLGAEALVRGASAIALRLGITPLIIGLTIVAFGTSAPELAVSVKSALAGNSGIALGNVIGSNIANI
GLILAITALIRPIQVQSQVVKRDIPLMILASMLFWGLLLDGELSLIDGVVLLSLLVGYLTFSYISSKNSKNEEEIEAGPN
NPLLSGLFILVGISMLVGGGILFVNGAVDLAKTFGVSEVIIGLTIVAIGTSMPELVTSVIAALKGQSDIAIGNVVGSNLF
NILGILGVTAIVHPVSSLGFQPFDFMVMLALAIVILPFAWTGLRIGRREGSVLLLTYLGYMGYLINQASAQALV

Sequences:

>Translated_314_residues
MLITLSIIGGFIILTLGAEALVRGASAIALRLGITPLIIGLTIVAFGTSAPELAVSVKSALAGNSGIALGNVIGSNIANI
GLILAITALIRPIQVQSQVVKRDIPLMILASMLFWGLLLDGELSLIDGVVLLSLLVGYLTFSYISSKNSKNEEEIEAGPN
NPLLSGLFILVGISMLVGGGILFVNGAVDLAKTFGVSEVIIGLTIVAIGTSMPELVTSVIAALKGQSDIAIGNVVGSNLF
NILGILGVTAIVHPVSSLGFQPFDFMVMLALAIVILPFAWTGLRIGRREGSVLLLTYLGYMGYLINQASAQALV
>Mature_314_residues
MLITLSIIGGFIILTLGAEALVRGASAIALRLGITPLIIGLTIVAFGTSAPELAVSVKSALAGNSGIALGNVIGSNIANI
GLILAITALIRPIQVQSQVVKRDIPLMILASMLFWGLLLDGELSLIDGVVLLSLLVGYLTFSYISSKNSKNEEEIEAGPN
NPLLSGLFILVGISMLVGGGILFVNGAVDLAKTFGVSEVIIGLTIVAIGTSMPELVTSVIAALKGQSDIAIGNVVGSNLF
NILGILGVTAIVHPVSSLGFQPFDFMVMLALAIVILPFAWTGLRIGRREGSVLLLTYLGYMGYLINQASAQALV

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI4759128, Length=81, Percent_Identity=46.9135802469136, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI45504369, Length=118, Percent_Identity=33.8983050847458, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789587, Length=274, Percent_Identity=37.956204379562, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 32492; Mature: 32492

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLITLSIIGGFIILTLGAEALVRGASAIALRLGITPLIIGLTIVAFGTSAPELAVSVKSA
CEEEEEHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LAGNSGIALGNVIGSNIANIGLILAITALIRPIQVQSQVVKRDIPLMILASMLFWGLLLD
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
GELSLIDGVVLLSLLVGYLTFSYISSKNSKNEEEIEAGPNNPLLSGLFILVGISMLVGGG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
ILFVNGAVDLAKTFGVSEVIIGLTIVAIGTSMPELVTSVIAALKGQSDIAIGNVVGSNLF
EEEEECHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
NILGILGVTAIVHPVSSLGFQPFDFMVMLALAIVILPFAWTGLRIGRREGSVLLLTYLGY
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEHHHHHHH
MGYLINQASAQALV
HHHHHHHHHHHCCC
>Mature Secondary Structure
MLITLSIIGGFIILTLGAEALVRGASAIALRLGITPLIIGLTIVAFGTSAPELAVSVKSA
CEEEEEHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LAGNSGIALGNVIGSNIANIGLILAITALIRPIQVQSQVVKRDIPLMILASMLFWGLLLD
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
GELSLIDGVVLLSLLVGYLTFSYISSKNSKNEEEIEAGPNNPLLSGLFILVGISMLVGGG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
ILFVNGAVDLAKTFGVSEVIIGLTIVAIGTSMPELVTSVIAALKGQSDIAIGNVVGSNLF
EEEEECHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
NILGILGVTAIVHPVSSLGFQPFDFMVMLALAIVILPFAWTGLRIGRREGSVLLLTYLGY
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEHHHHHHH
MGYLINQASAQALV
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]