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The map label for this gene is fabF [H]

Identifier: 160873460

GI number: 160873460

Start: 380910

End: 382130

Strand: Reverse

Name: fabF [H]

Synonym: Sbal195_0335

Alternate gene names: 160873460

Gene position: 382130-380910 (Counterclockwise)

Preceding gene: 160873461

Following gene: 160873459

Centisome position: 7.15

GC content: 53.15

Gene sequence:

>1221_bases
ATGGTAAAAAAACGATACGCTATGATGAACAGAGTAGCCATTACACAGATTGGATTGTGTACCCCGCTAGGGCAAGATCC
CCAGCAGGTTTTAGACCGCCTGATCGCGGGTGATACCAGCGCGATGCAGCGCAGTGACACACTCCTGTTCGAGCACCCAA
CCTTAGTTGCACCAGTAACGGCAGCGCTACCGGCGATTCCTGCAAAGCTTATTCAGTTCGATTGCCGCAATAACCAGTTA
CTCCTTTGCGCGGCGCAGCAAATTGCCGCCACGATTGAACAAGCGAAACGGGATTTGGGTCATGCCCGCATTGGCGTTGT
GCTAGGCACGAGCACCTCGGGGATTTCTAAAGGTGAAGCGGCCCTGAGCTATCGCAATCAACACGGCCACTTTCCGGCGG
ATTACCACTATTTCCAACAGGAGCTCGGCAGCACTAGCGACTTTTTGCGCCAATATTTTGAGCTAGATGGCCCTTGCTAC
ACAATTTCAACCGCCTGTTCCTCCAGCGCAAAAGTCTTTGCCAGTGCCAAACGTTTACTCAGCGCTAACCTCTGTGACAT
GGTGATTGTTGGCGGTGTCGACAGTTTGTGCCAACTGACAGTCAATGGTTTTAATGCTTTGGAATCTGTATCCAAAGGCC
ACTGCAATCCCTTTAGTATCAACCGTGATGGCATCAATATTGGCGAAGGCGCGGCCTTATTCGTGCTGGCGGCGGGCGAG
TCCGATGTGATGCTAGCGGGCATTGGCGAGTCGAGCGATGCCCATCATATTTCGGCGCCACACCCCGAAGGCGTTGGCGC
AATCACCGCCATGCAAGCGGCTTTGCAAGATGCAAATATTGCGGCACAAGACATTGGTTACATTAACTTACACGGCACAG
CGACACCCAAAAATGATGCGATGGAAAGCCGCGCTGTGGTTGAAGTATTTGGCGTCAACACACCACCCTGCAGCTCGACT
AAACCCTTAGTCGGCCATACCTTAGGTGCCGCTGGCGCAATTGAAGCCGCCTTCTGCTATTTATTGCTTTCGGCACATAA
TCGCGACCAAGCCCTGCCGCCCCATCAATGGGACGGACAAGTCGATCCGCAGGATCCGTCCATAGCCTTAGTCGAACGCC
ATCGAGTCGCCGCCAAAGGCGCACTTAACTATGTGATGAGTAATTCCTTCGCCTTTGGCGGCAGCAATGCCAGCCTGATT
TTTTGCCGTAACGAGGCCTAG

Upstream 100 bases:

>100_bases
GCCCTATGGCAAGCCCACATCAGCTTAACTATGCCGCAGGCCAAGTTTGAGCTAGAAATCGAACCTATTTAACCTTTTAA
CACCCGCACTTCACTGTGCC

Downstream 100 bases:

>100_bases
TACCATGCAGTTACTTAAAATTAACCAACCCTTTGCCGAACAAGATATTGCCGACTTTATTCCCCATAGGGCACCAATGA
TTTTGCTCGATAAAGTCATT

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MVKKRYAMMNRVAITQIGLCTPLGQDPQQVLDRLIAGDTSAMQRSDTLLFEHPTLVAPVTAALPAIPAKLIQFDCRNNQL
LLCAAQQIAATIEQAKRDLGHARIGVVLGTSTSGISKGEAALSYRNQHGHFPADYHYFQQELGSTSDFLRQYFELDGPCY
TISTACSSSAKVFASAKRLLSANLCDMVIVGGVDSLCQLTVNGFNALESVSKGHCNPFSINRDGINIGEGAALFVLAAGE
SDVMLAGIGESSDAHHISAPHPEGVGAITAMQAALQDANIAAQDIGYINLHGTATPKNDAMESRAVVEVFGVNTPPCSST
KPLVGHTLGAAGAIEAAFCYLLLSAHNRDQALPPHQWDGQVDPQDPSIALVERHRVAAKGALNYVMSNSFAFGGSNASLI
FCRNEA

Sequences:

>Translated_406_residues
MVKKRYAMMNRVAITQIGLCTPLGQDPQQVLDRLIAGDTSAMQRSDTLLFEHPTLVAPVTAALPAIPAKLIQFDCRNNQL
LLCAAQQIAATIEQAKRDLGHARIGVVLGTSTSGISKGEAALSYRNQHGHFPADYHYFQQELGSTSDFLRQYFELDGPCY
TISTACSSSAKVFASAKRLLSANLCDMVIVGGVDSLCQLTVNGFNALESVSKGHCNPFSINRDGINIGEGAALFVLAAGE
SDVMLAGIGESSDAHHISAPHPEGVGAITAMQAALQDANIAAQDIGYINLHGTATPKNDAMESRAVVEVFGVNTPPCSST
KPLVGHTLGAAGAIEAAFCYLLLSAHNRDQALPPHQWDGQVDPQDPSIALVERHRVAAKGALNYVMSNSFAFGGSNASLI
FCRNEA
>Mature_406_residues
MVKKRYAMMNRVAITQIGLCTPLGQDPQQVLDRLIAGDTSAMQRSDTLLFEHPTLVAPVTAALPAIPAKLIQFDCRNNQL
LLCAAQQIAATIEQAKRDLGHARIGVVLGTSTSGISKGEAALSYRNQHGHFPADYHYFQQELGSTSDFLRQYFELDGPCY
TISTACSSSAKVFASAKRLLSANLCDMVIVGGVDSLCQLTVNGFNALESVSKGHCNPFSINRDGINIGEGAALFVLAAGE
SDVMLAGIGESSDAHHISAPHPEGVGAITAMQAALQDANIAAQDIGYINLHGTATPKNDAMESRAVVEVFGVNTPPCSST
KPLVGHTLGAAGAIEAAFCYLLLSAHNRDQALPPHQWDGQVDPQDPSIALVERHRVAAKGALNYVMSNSFAFGGSNASLI
FCRNEA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=430, Percent_Identity=32.3255813953488, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI223972627, Length=156, Percent_Identity=42.3076923076923, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1787337, Length=269, Percent_Identity=37.9182156133829, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1788663, Length=425, Percent_Identity=28.2352941176471, Blast_Score=121, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71983541, Length=418, Percent_Identity=27.0334928229665, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71983535, Length=262, Percent_Identity=30.9160305343511, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=265, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320904, Length=453, Percent_Identity=25.3863134657837, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24644341, Length=426, Percent_Identity=32.1596244131455, Blast_Score=156, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43004; Mature: 43004

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKKRYAMMNRVAITQIGLCTPLGQDPQQVLDRLIAGDTSAMQRSDTLLFEHPTLVAPVT
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCEEEECCCHHHHHH
AALPAIPAKLIQFDCRNNQLLLCAAQQIAATIEQAKRDLGHARIGVVLGTSTSGISKGEA
HHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHH
ALSYRNQHGHFPADYHYFQQELGSTSDFLRQYFELDGPCYTISTACSSSAKVFASAKRLL
HHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEHHCCCCHHHHHHHHHHH
SANLCDMVIVGGVDSLCQLTVNGFNALESVSKGHCNPFSINRDGINIGEGAALFVLAAGE
HCCCHHEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEECCC
SDVMLAGIGESSDAHHISAPHPEGVGAITAMQAALQDANIAAQDIGYINLHGTATPKNDA
CCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCCHH
MESRAVVEVFGVNTPPCSSTKPLVGHTLGAAGAIEAAFCYLLLSAHNRDQALPPHQWDGQ
HHHCCEEEEECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
VDPQDPSIALVERHRVAAKGALNYVMSNSFAFGGSNASLIFCRNEA
CCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCC
>Mature Secondary Structure
MVKKRYAMMNRVAITQIGLCTPLGQDPQQVLDRLIAGDTSAMQRSDTLLFEHPTLVAPVT
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCEEEECCCHHHHHH
AALPAIPAKLIQFDCRNNQLLLCAAQQIAATIEQAKRDLGHARIGVVLGTSTSGISKGEA
HHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHH
ALSYRNQHGHFPADYHYFQQELGSTSDFLRQYFELDGPCYTISTACSSSAKVFASAKRLL
HHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEHHCCCCHHHHHHHHHHH
SANLCDMVIVGGVDSLCQLTVNGFNALESVSKGHCNPFSINRDGINIGEGAALFVLAAGE
HCCCHHEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEECCC
SDVMLAGIGESSDAHHISAPHPEGVGAITAMQAALQDANIAAQDIGYINLHGTATPKNDA
CCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCCHH
MESRAVVEVFGVNTPPCSSTKPLVGHTLGAAGAIEAAFCYLLLSAHNRDQALPPHQWDGQ
HHHCCEEEEECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
VDPQDPSIALVERHRVAAKGALNYVMSNSFAFGGSNASLIFCRNEA
CCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10784042; 11481430 [H]