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The map label for this gene is fabB [H]

Identifier: 160873457

GI number: 160873457

Start: 378220

End: 379479

Strand: Reverse

Name: fabB [H]

Synonym: Sbal195_0332

Alternate gene names: 160873457

Gene position: 379479-378220 (Counterclockwise)

Preceding gene: 160873458

Following gene: 160873456

Centisome position: 7.1

GC content: 53.41

Gene sequence:

>1260_bases
ATGAGCGAGGCGACAAATCAAACACGTTTAGGTAAGCGAGTGGTCATCACAGGCATTGGCGGGATTACCGCACTAGGCCA
TGATTGGCCGACGATAGCGGCGAGCCTTAAGGCGCAGAAAAACTGCGTCGTCACTATGAGTGACTGGGATAGATACGACG
GCCTCAACACCCGTTTAGCCGCGCCAATTACTGACTTTGAAGTGCCAAGCCATTATTCACGCAAGAAAATTCGTTCTATG
GGTCGGGTTTCCATCATGGCGACTCGCGCCAGTGAGCTTGCTTTACTCGATGCGGGGTTGTTGGATGACCCTATCGTGTC
CTCGGGTGAAATGGGCATCGCCTACGGTTCATCCACGGGCAGTACCGATCCTATAACCGCCTTTGGCGATATGCTGAAAA
CCGGTGATATGTCGGGCGTCACCGCCACTAGCTATATCCGCATGATGGCGCACACCACAGCGGTGAACGTTGGCGTATTC
TTCGGCTTAAAGGGCCGAATTCACACCACCAGCAGCGCATGCACTTCGGGGAGCCAAGGCATAGGTTATGCCTATGAAGC
CATCAAATACGGTCAGCAAACCTTAATGCTAGCGGGCGGCGGCGAAGAACTCTGTCCCACCGAAGCTGTGGTGTTCGATA
CCCTGTTTGCCACCAGCACTAAAAACTCGACGCCCGAACTCACGCCACGCCCCTTTGATGCAGATCGCGATGGCCTCGTC
ATTGGCGAAGGGGCTTGTACGCTGGTGCTCGAAGAGCTCGAACACGCCAAGGCGCGTGGCGCAAAAATTTATGCTGAGTT
AGTCGGTTTTGGCACAAATTCCGACGGTCAACACGTCACCCAACCGAATGCGCAGACCATGGAAATCGCCATCAGATTAG
CCCTCAAAGATGCGCAGCTTGAGCCTAGCGCCATAGGTTATGTGAACGCCCACGGCACAGCCACCGACCGTGGTGACATT
GCTGAGAGTCACGCGACTCACGCGGTATTTGGCACTAACATGCCGATTTCATCCCTAAAAAGCTACACGGGCCACACCTT
AGGTGCATGCGGCGCGCTAGAAGCTTGGGTGAGTATTGAGATGATGAATGCGGGCTGGTTTGCGCCAACACTCAATCTTG
AGAATATCGACCCACAGTGCGCCGATTTGGACTATATCCGTAACGAACTGCGCCCGATCGACACAGATTATGTCATGAGT
AATAATTTCGCCTTTGGCGGCATTAATACCTCGCTGATTTTTAAACGCTGGACCAGATAA

Upstream 100 bases:

>100_bases
TAAACCCAATGAAATCGCCGCCTTAGCCGCATTTTTAATGTCTGACGATGCAGCCTATATCACTCGCCAAGTGATATCGG
TCAATGGAGGCATGATCTAA

Downstream 100 bases:

>100_bases
CACCTAAAACCCACATAAGGACATAGCAATGAAACCACTGTTTGCAGGGATGCTGCTGAGCATCAGTTTATTAACCGCGC
CACTGTTTGCCAAAGAATAC

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase I; Beta-ketoacyl-ACP synthase I; KAS I [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSEATNQTRLGKRVVITGIGGITALGHDWPTIAASLKAQKNCVVTMSDWDRYDGLNTRLAAPITDFEVPSHYSRKKIRSM
GRVSIMATRASELALLDAGLLDDPIVSSGEMGIAYGSSTGSTDPITAFGDMLKTGDMSGVTATSYIRMMAHTTAVNVGVF
FGLKGRIHTTSSACTSGSQGIGYAYEAIKYGQQTLMLAGGGEELCPTEAVVFDTLFATSTKNSTPELTPRPFDADRDGLV
IGEGACTLVLEELEHAKARGAKIYAELVGFGTNSDGQHVTQPNAQTMEIAIRLALKDAQLEPSAIGYVNAHGTATDRGDI
AESHATHAVFGTNMPISSLKSYTGHTLGACGALEAWVSIEMMNAGWFAPTLNLENIDPQCADLDYIRNELRPIDTDYVMS
NNFAFGGINTSLIFKRWTR

Sequences:

>Translated_419_residues
MSEATNQTRLGKRVVITGIGGITALGHDWPTIAASLKAQKNCVVTMSDWDRYDGLNTRLAAPITDFEVPSHYSRKKIRSM
GRVSIMATRASELALLDAGLLDDPIVSSGEMGIAYGSSTGSTDPITAFGDMLKTGDMSGVTATSYIRMMAHTTAVNVGVF
FGLKGRIHTTSSACTSGSQGIGYAYEAIKYGQQTLMLAGGGEELCPTEAVVFDTLFATSTKNSTPELTPRPFDADRDGLV
IGEGACTLVLEELEHAKARGAKIYAELVGFGTNSDGQHVTQPNAQTMEIAIRLALKDAQLEPSAIGYVNAHGTATDRGDI
AESHATHAVFGTNMPISSLKSYTGHTLGACGALEAWVSIEMMNAGWFAPTLNLENIDPQCADLDYIRNELRPIDTDYVMS
NNFAFGGINTSLIFKRWTR
>Mature_418_residues
SEATNQTRLGKRVVITGIGGITALGHDWPTIAASLKAQKNCVVTMSDWDRYDGLNTRLAAPITDFEVPSHYSRKKIRSMG
RVSIMATRASELALLDAGLLDDPIVSSGEMGIAYGSSTGSTDPITAFGDMLKTGDMSGVTATSYIRMMAHTTAVNVGVFF
GLKGRIHTTSSACTSGSQGIGYAYEAIKYGQQTLMLAGGGEELCPTEAVVFDTLFATSTKNSTPELTPRPFDADRDGLVI
GEGACTLVLEELEHAKARGAKIYAELVGFGTNSDGQHVTQPNAQTMEIAIRLALKDAQLEPSAIGYVNAHGTATDRGDIA
ESHATHAVFGTNMPISSLKSYTGHTLGACGALEAWVSIEMMNAGWFAPTLNLENIDPQCADLDYIRNELRPIDTDYVMSN
NFAFGGINTSLIFKRWTR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=421, Percent_Identity=34.916864608076, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI41872631, Length=280, Percent_Identity=30.7142857142857, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI223972627, Length=162, Percent_Identity=36.4197530864198, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1788663, Length=409, Percent_Identity=37.1638141809291, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787337, Length=415, Percent_Identity=37.8313253012048, Blast_Score=231, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI71983541, Length=414, Percent_Identity=32.1256038647343, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=37.5, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI212642053, Length=347, Percent_Identity=27.0893371757925, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17550940, Length=265, Percent_Identity=25.6603773584906, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=32.4384787472036, Blast_Score=197, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24644341, Length=424, Percent_Identity=34.1981132075472, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI19920632, Length=357, Percent_Identity=25.2100840336134, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221330659, Length=357, Percent_Identity=25.2100840336134, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581345, Length=342, Percent_Identity=25.4385964912281, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: 24024 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 30,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 44802; Mature: 44671

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEATNQTRLGKRVVITGIGGITALGHDWPTIAASLKAQKNCVVTMSDWDRYDGLNTRLA
CCCCCCCHHCCCEEEEEECCCCEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEE
APITDFEVPSHYSRKKIRSMGRVSIMATRASELALLDAGLLDDPIVSSGEMGIAYGSSTG
CCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCC
STDPITAFGDMLKTGDMSGVTATSYIRMMAHTTAVNVGVFFGLKGRIHTTSSACTSGSQG
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCEEEECCHHCCCCCCC
IGYAYEAIKYGQQTLMLAGGGEELCPTEAVVFDTLFATSTKNSTPELTPRPFDADRDGLV
CHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
IGEGACTLVLEELEHAKARGAKIYAELVGFGTNSDGQHVTQPNAQTMEIAIRLALKDAQL
EECCHHHHHHHHHHHHHHCCCEEEEEHEECCCCCCCCEECCCCCCEEEEEEEEEEECCCC
EPSAIGYVNAHGTATDRGDIAESHATHAVFGTNMPISSLKSYTGHTLGACGALEAWVSIE
CCCEEEEEECCCCCCCCCCCHHHCCCEEEEECCCCHHHHHHHCCCCHHHHHHHHHEEEEE
MMNAGWFAPTLNLENIDPQCADLDYIRNELRPIDTDYVMSNNFAFGGINTSLIFKRWTR
EECCCCCEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCEEECCCCCEEEEEECCC
>Mature Secondary Structure 
SEATNQTRLGKRVVITGIGGITALGHDWPTIAASLKAQKNCVVTMSDWDRYDGLNTRLA
CCCCCCHHCCCEEEEEECCCCEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEE
APITDFEVPSHYSRKKIRSMGRVSIMATRASELALLDAGLLDDPIVSSGEMGIAYGSSTG
CCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCC
STDPITAFGDMLKTGDMSGVTATSYIRMMAHTTAVNVGVFFGLKGRIHTTSSACTSGSQG
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCEEEECCHHCCCCCCC
IGYAYEAIKYGQQTLMLAGGGEELCPTEAVVFDTLFATSTKNSTPELTPRPFDADRDGLV
CHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
IGEGACTLVLEELEHAKARGAKIYAELVGFGTNSDGQHVTQPNAQTMEIAIRLALKDAQL
EECCHHHHHHHHHHHHHHCCCEEEEEHEECCCCCCCCEECCCCCCEEEEEEEEEEECCCC
EPSAIGYVNAHGTATDRGDIAESHATHAVFGTNMPISSLKSYTGHTLGACGALEAWVSIE
CCCEEEEEECCCCCCCCCCCHHHCCCEEEEECCCCHHHHHHHCCCCHHHHHHHHHEEEEE
MMNAGWFAPTLNLENIDPQCADLDYIRNELRPIDTDYVMSNNFAFGGINTSLIFKRWTR
EECCCCCEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]