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The map label for this gene is dtd [H]

Identifier: 160873447

GI number: 160873447

Start: 366638

End: 367075

Strand: Direct

Name: dtd [H]

Synonym: Sbal195_0322

Alternate gene names: 160873447

Gene position: 366638-367075 (Clockwise)

Preceding gene: 160873446

Following gene: 160873448

Centisome position: 6.86

GC content: 50.68

Gene sequence:

>438_bases
GTGATTGCGTTAATTCAAAGAGTGAGCCGCGCCAGTGTGGTTGTCGATAATCAAACCATAGGTGCAATCGATAAGGGCCT
GTTGGTTCTGCTGGGCGTCGAGCAGGAAGATACCCGCGAGAAGATGGAAAAACTGGCAACTAAAGTGATGAGTTATCGCG
TGTTTTCCGATGAAAATGGCAAGATGAATCTCAACCTAGAGCAAGTCGGTGGATCTTTGTTAGTGGTGTCGCAATTTACC
TTGGCCGCCGATACGGGCCGTGGCTTGAGACCGAGTTTTTCTGGCGCCGGTACGCCGGATCAAGCCTTGGCACTGTATGA
AGAGTTTGTCGCATTTTGCCGCGCTAAGGGCGTGACCACAGAAACCGGACAATTCGGCGCCGATATGCAAGTGTCCTTAG
TCAATGATGGCCCAGTGACTTTTAATCTGCAGGTGTAG

Upstream 100 bases:

>100_bases
TCGCGCAATCCTTGCCAGATGGCATCGATCAATATATTCGTCCTATCCCGCTCATGCAGCAAATGGTTCCCGTTAAGCCT
TAATCTAAAAAGGAAAAGTT

Downstream 100 bases:

>100_bases
CTTCTTATCGCGCGAGTGATTGCGTTAGTTATTGTGTTAGCAATTACGTTAGCTATTAAATTAGTCATCGCGTGGTTTTT
CTGGGGGATAGAGTGTTGGA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIALIQRVSRASVVVDNQTIGAIDKGLLVLLGVEQEDTREKMEKLATKVMSYRVFSDENGKMNLNLEQVGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPDQALALYEEFVAFCRAKGVTTETGQFGADMQVSLVNDGPVTFNLQV

Sequences:

>Translated_145_residues
MIALIQRVSRASVVVDNQTIGAIDKGLLVLLGVEQEDTREKMEKLATKVMSYRVFSDENGKMNLNLEQVGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPDQALALYEEFVAFCRAKGVTTETGQFGADMQVSLVNDGPVTFNLQV
>Mature_145_residues
MIALIQRVSRASVVVDNQTIGAIDKGLLVLLGVEQEDTREKMEKLATKVMSYRVFSDENGKMNLNLEQVGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPDQALALYEEFVAFCRAKGVTTETGQFGADMQVSLVNDGPVTFNLQV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=152, Percent_Identity=40.7894736842105, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=64.8275862068965, Blast_Score=194, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=39.1891891891892, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=41.0958904109589, Blast_Score=111, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=37.6712328767123, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 15603; Mature: 15603

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVSRASVVVDNQTIGAIDKGLLVLLGVEQEDTREKMEKLATKVMSYRVFSDENG
CHHHHHHHHHCEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCC
KMNLNLEQVGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQALALYEEFVAFCRAKGVTT
EEEEEHHHHCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
ETGQFGADMQVSLVNDGPVTFNLQV
CCCCCCCCEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MIALIQRVSRASVVVDNQTIGAIDKGLLVLLGVEQEDTREKMEKLATKVMSYRVFSDENG
CHHHHHHHHHCEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCC
KMNLNLEQVGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQALALYEEFVAFCRAKGVTT
EEEEEHHHHCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
ETGQFGADMQVSLVNDGPVTFNLQV
CCCCCCCCEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA