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The map label for this gene is ccmA [H]

Identifier: 160873357

GI number: 160873357

Start: 266175

End: 266825

Strand: Reverse

Name: ccmA [H]

Synonym: Sbal195_0231

Alternate gene names: 160873357

Gene position: 266825-266175 (Counterclockwise)

Preceding gene: 160873359

Following gene: 160873356

Centisome position: 4.99

GC content: 42.7

Gene sequence:

>651_bases
GTGACAAATATAACTAAAGAAACCACATTAGTGTCAGCCAGCAAGCTGACCTGTATCCGCGAAGAACGCATCCTTTTTGA
TGAGTTAAGTTTTGATATTAATGCCGGTGATATTGTTCAAATTGAAGGCCCTAACGGCGCGGGCAAAACCAGTTTATTAC
GCATATTGGCAGGTCTTTCTCGCCCCTATGCCGGACAAACCTTTTACAGAAATGAAGACATAAACCGCTGCCGTGATGAA
TACAATGAAGATCTCTTGTATCTCGGCCATTTAGCGGGAGTGAAATGCGAGCTTACCGCCGAAGAAAACCTTAATTTCAA
TTTAAGAATCAGTGGCTATGATGACTTTGATACCTCAGCCATTTTAGCCAAAGTGAACTTAACAGGTTTTGAAGAGGCGC
TTGCCGGACATTTATCCGCAGGCCAGCATCGCAGAACCGCGCTATCGAGATTGTGGCATAGCAATTGTAAAATTTGGATC
CTTGACGAACCTTTTACCGCGATCGATAAAAAAGGCGTCGAAGAGCTGGAGCAATTATTTATTCAGCATGCGGATAATGG
TGGTTGTGTGATCCTCACAACTCACCAAGATATGGGCATTATCAAAGATGATAGGCTTCGTAAAATTCGTCTAGATTATC
GCTTCATATAA

Upstream 100 bases:

>100_bases
CATCATATTGCTGACATCTAGTGCAAACCAAGAGTAAACCCCCAATAACGTTTGTGTTAGAATAACTTGTGTTTCCTTCC
GGCTTGAGATAGAGGGTTCA

Downstream 100 bases:

>100_bases
GGTCAGGCTAAATGAAAAGAGGCATCAGTTTTACCCAGGCATTTTTCACCTTGCTGCAGCGAGATCTTAAAATTGCCATT
CGTCACCGCGGCGACATTTT

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTNITKETTLVSASKLTCIREERILFDELSFDINAGDIVQIEGPNGAGKTSLLRILAGLSRPYAGQTFYRNEDINRCRDE
YNEDLLYLGHLAGVKCELTAEENLNFNLRISGYDDFDTSAILAKVNLTGFEEALAGHLSAGQHRRTALSRLWHSNCKIWI
LDEPFTAIDKKGVEELEQLFIQHADNGGCVILTTHQDMGIIKDDRLRKIRLDYRFI

Sequences:

>Translated_216_residues
MTNITKETTLVSASKLTCIREERILFDELSFDINAGDIVQIEGPNGAGKTSLLRILAGLSRPYAGQTFYRNEDINRCRDE
YNEDLLYLGHLAGVKCELTAEENLNFNLRISGYDDFDTSAILAKVNLTGFEEALAGHLSAGQHRRTALSRLWHSNCKIWI
LDEPFTAIDKKGVEELEQLFIQHADNGGCVILTTHQDMGIIKDDRLRKIRLDYRFI
>Mature_215_residues
TNITKETTLVSASKLTCIREERILFDELSFDINAGDIVQIEGPNGAGKTSLLRILAGLSRPYAGQTFYRNEDINRCRDEY
NEDLLYLGHLAGVKCELTAEENLNFNLRISGYDDFDTSAILAKVNLTGFEEALAGHLSAGQHRRTALSRLWHSNCKIWIL
DEPFTAIDKKGVEELEQLFIQHADNGGCVILTTHQDMGIIKDDRLRKIRLDYRFI

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=182, Percent_Identity=32.4175824175824, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI45446740, Length=178, Percent_Identity=29.2134831460674, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI47078218, Length=178, Percent_Identity=29.2134831460674, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI27881501, Length=182, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI30795238, Length=182, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI153792144, Length=194, Percent_Identity=25.2577319587629, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21536376, Length=192, Percent_Identity=25, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI150417984, Length=182, Percent_Identity=26.3736263736264, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI87082064, Length=205, Percent_Identity=49.7560975609756, Blast_Score=183, Evalue=7e-48,
Organism=Escherichia coli, GI87081709, Length=149, Percent_Identity=31.5436241610738, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788761, Length=180, Percent_Identity=30.5555555555556, Blast_Score=80, Evalue=7e-17,
Organism=Escherichia coli, GI87081791, Length=208, Percent_Identity=27.8846153846154, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081782, Length=166, Percent_Identity=33.1325301204819, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787105, Length=194, Percent_Identity=27.319587628866, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787370, Length=192, Percent_Identity=27.6041666666667, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI2367384, Length=198, Percent_Identity=26.2626262626263, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789593, Length=194, Percent_Identity=26.2886597938144, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788165, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786563, Length=182, Percent_Identity=27.4725274725275, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789873, Length=194, Percent_Identity=26.8041237113402, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1786253, Length=155, Percent_Identity=29.6774193548387, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1787029, Length=180, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789991, Length=182, Percent_Identity=27.4725274725275, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787164, Length=175, Percent_Identity=30.2857142857143, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790467, Length=153, Percent_Identity=25.4901960784314, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=201, Percent_Identity=28.8557213930348, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666092, Length=190, Percent_Identity=30.5263157894737, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648314, Length=189, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 24451; Mature: 24320

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNITKETTLVSASKLTCIREERILFDELSFDINAGDIVQIEGPNGAGKTSLLRILAGLS
CCCCCCCCEEEEHHHHHHHHHHHHEEEHHCEECCCCCEEEEECCCCCCHHHHHHHHHHCC
RPYAGQTFYRNEDINRCRDEYNEDLLYLGHLAGVKCELTAEENLNFNLRISGYDDFDTSA
CCCCCCCEECCCCHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCCCE
ILAKVNLTGFEEALAGHLSAGQHRRTALSRLWHSNCKIWILDEPFTAIDKKGVEELEQLF
EEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCHHHHHHHH
IQHADNGGCVILTTHQDMGIIKDDRLRKIRLDYRFI
HHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure 
TNITKETTLVSASKLTCIREERILFDELSFDINAGDIVQIEGPNGAGKTSLLRILAGLS
CCCCCCCEEEEHHHHHHHHHHHHEEEHHCEECCCCCEEEEECCCCCCHHHHHHHHHHCC
RPYAGQTFYRNEDINRCRDEYNEDLLYLGHLAGVKCELTAEENLNFNLRISGYDDFDTSA
CCCCCCCEECCCCHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCCCE
ILAKVNLTGFEEALAGHLSAGQHRRTALSRLWHSNCKIWILDEPFTAIDKKGVEELEQLF
EEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCHHHHHHHH
IQHADNGGCVILTTHQDMGIIKDDRLRKIRLDYRFI
HHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]