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The map label for this gene is rhtB [H]

Identifier: 160873249

GI number: 160873249

Start: 144730

End: 145353

Strand: Reverse

Name: rhtB [H]

Synonym: Sbal195_0123

Alternate gene names: 160873249

Gene position: 145353-144730 (Counterclockwise)

Preceding gene: 160873250

Following gene: 160873247

Centisome position: 2.72

GC content: 49.2

Gene sequence:

>624_bases
ATGCAACCTGAAACTTGGTTACTCTATCTCTTGGCCATTGTATTGATTGGGATCTCACCCGGCCCCATCGCTATGTTGTC
TATGTCCCACGGGATCCATTTCGGTAAGATGCGCAGCATGGCCACTGGTCTTGGCAGTGTGAGTGCCGCATTAGTCTTGA
TGATGGCATCAGCGGCGGGATTAGGCGCCATTATCAGCGCCTCAGAATACGGTTTTACCCTGCTAAAATGGTGCGGTGCG
GCCTATTTAGTATTTTTAGGGATCAAGCTGCTGTTGACCAAAAACCAAGGTCAAACCCTTGAGGTTAGCCAATTAAAAGG
CAAAGGCACGCCAAGGCAACTTTATCAGCAGGCGTTTCTGGTGGGGATCAGTAATCCCAAGGATTTACTGTTTTTTGCCG
CGCTGTTTCCGCAATTTATCGATCTTGCCGCGCCGCAATTACCGCAACTCATGATACTTGCAGCCACTTGGGCTGTGGTA
GATTTTAGCTTTGTGATGATTTACGCCAGCATGGCCAATGTGCTTGCGCCCAGCCTAAAGGCGAGCAACAAGCTGCATTG
GTTTGACAGAACCAGCGGCGGTGTCTTTCTTACCTTAGCCGCGATTCTTATCTCTCGAAATTAA

Upstream 100 bases:

>100_bases
TGAGCTTCTATCGCACCATTAAAGGCCGCCATCCTAAGGTGATCCCTGATTTTGTGACGAGTGCGAAACATTAATATTTT
CCCCATTTAGAGCGGCACAC

Downstream 100 bases:

>100_bases
ATCAATAATCGTCGACAGTCATTAACACTAGTCAACCTTAACCGACTTTAAGCTACGAATATCGTTGCCCGTTGGCGCTT
GGAATGCCTGCAGACCAAAC

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MQPETWLLYLLAIVLIGISPGPIAMLSMSHGIHFGKMRSMATGLGSVSAALVLMMASAAGLGAIISASEYGFTLLKWCGA
AYLVFLGIKLLLTKNQGQTLEVSQLKGKGTPRQLYQQAFLVGISNPKDLLFFAALFPQFIDLAAPQLPQLMILAATWAVV
DFSFVMIYASMANVLAPSLKASNKLHWFDRTSGGVFLTLAAILISRN

Sequences:

>Translated_207_residues
MQPETWLLYLLAIVLIGISPGPIAMLSMSHGIHFGKMRSMATGLGSVSAALVLMMASAAGLGAIISASEYGFTLLKWCGA
AYLVFLGIKLLLTKNQGQTLEVSQLKGKGTPRQLYQQAFLVGISNPKDLLFFAALFPQFIDLAAPQLPQLMILAATWAVV
DFSFVMIYASMANVLAPSLKASNKLHWFDRTSGGVFLTLAAILISRN
>Mature_207_residues
MQPETWLLYLLAIVLIGISPGPIAMLSMSHGIHFGKMRSMATGLGSVSAALVLMMASAAGLGAIISASEYGFTLLKWCGA
AYLVFLGIKLLLTKNQGQTLEVSQLKGKGTPRQLYQQAFLVGISNPKDLLFFAALFPQFIDLAAPQLPQLMILAATWAVV
DFSFVMIYASMANVLAPSLKASNKLHWFDRTSGGVFLTLAAILISRN

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=205, Percent_Identity=33.1707317073171, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1788099, Length=160, Percent_Identity=28.75, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22254; Mature: 22254

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPETWLLYLLAIVLIGISPGPIAMLSMSHGIHFGKMRSMATGLGSVSAALVLMMASAAG
CCCHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCC
LGAIISASEYGFTLLKWCGAAYLVFLGIKLLLTKNQGQTLEVSQLKGKGTPRQLYQQAFL
CHHHEECCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHCCCCCHHHHHHHHHH
VGISNPKDLLFFAALFPQFIDLAAPQLPQLMILAATWAVVDFSFVMIYASMANVLAPSLK
HCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASNKLHWFDRTSGGVFLTLAAILISRN
CCCCEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQPETWLLYLLAIVLIGISPGPIAMLSMSHGIHFGKMRSMATGLGSVSAALVLMMASAAG
CCCHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCC
LGAIISASEYGFTLLKWCGAAYLVFLGIKLLLTKNQGQTLEVSQLKGKGTPRQLYQQAFL
CHHHEECCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHCCCCCHHHHHHHHHH
VGISNPKDLLFFAALFPQFIDLAAPQLPQLMILAATWAVVDFSFVMIYASMANVLAPSLK
HCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASNKLHWFDRTSGGVFLTLAAILISRN
CCCCEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]