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The map label for this gene is kdpD [H]

Identifier: 160873183

GI number: 160873183

Start: 65323

End: 66369

Strand: Reverse

Name: kdpD [H]

Synonym: Sbal195_0057

Alternate gene names: 160873183

Gene position: 66369-65323 (Counterclockwise)

Preceding gene: 160873184

Following gene: 160873182

Centisome position: 1.24

GC content: 50.62

Gene sequence:

>1047_bases
ATGACTTCATCCATAGCGGCTCCCATGACTCAATACTGGCGTTCGCACCCAACATTTTTTACCGGCACAGTGCTAGTTAT
CGCGATTTTTAGCAGTGCTTTTATCGATTATTTTGCTGGCTCCACCATAGCCGTGCTGCTGATTTTACAATTAGCCGTGG
TCGCAGTGGCCCTGCAATGCAACGCTAACTTTGCCTATTTTGCAGCTGTGTTTGAGGCGACAAGCTTTAATTTTCTGTTT
ACCACGCCGCGCTATTCGCTACAGATGTTCAATCTTGAGGACATTCTCAATTTAACTGTGTTTCTACTTGTCGCTCTGAC
CACCAGCAAATTGGCCGAACTTTATCGCCGCCAGCAAGCGGCACTCGAACAGGCTCAGTTACGCAACAGCATCTTATTGT
CGGTTTCCCATGACTTACGCACCCCGCTCTCAACCATCATAGGTACCCTGACAACCCTGAAGGAATACATGCCTAAGCTC
AGTGCGTCGCAAAAGACTGAGCTGATTGATAGCGCGGCTGCCGAGAGTCATCGTCTGCATCAATATATCGAAAACCTGTT
ACAGGCCACTAAGTTACAACACGGCGCCCTCAAGTTCAGCCTGAGTGAAGACGCCATGATGAATGTGTTACACCAAGCTA
TCGGCCGCTTTCCCGCCGCGCAGCCGCGAATTGTCATCGACAGCGAGGCCGAACTGCCGCCGCTGATGATCAGCAGCTCT
TTGATTGAACAGGCCATTTTTAATGTGCTGGATAATGCGCTGCGCTATTCACCCTTAGATAAACCCGTCACAGTAAAGGC
TTACCAGCAGGGCGATATGCTGCGGTTAGATATTCAAGATGAGGGCGTAGGCATCGCCGCCGCAGAGGCGCAGGCTATTT
TTGAACTCTTTTATCGTCAGCATCCCTCAACTGATGGCGGCGCAGGCCTTGGGCTTGCCGTTGCTAAGGGCATTATTACC
GCCCATGGCGGCCAGATCAGCGCCGAACCTGTGGCAAAGGGCAGCCTTATTCGTATTGCTTTGCCGATTAAAAAGGGAGA
GCAATAA

Upstream 100 bases:

>100_bases
AGCTACTCACTGGGCTATAAATTTTACGGATTTTTTACGCGCTATCTTAAAATGGCTTTGTTAGAGTACAGACACTTTCT
TTATATGCGTCTTTCTATCC

Downstream 100 bases:

>100_bases
ATGGCTTACAAGGTGCTGGTTGTCGATGACGAAGCGCAAATTCACACTTTTATGCGGATATCGTTAGAAGCGGAAGGCTT
TGAATATCATGGCGCCGCCT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTSSIAAPMTQYWRSHPTFFTGTVLVIAIFSSAFIDYFAGSTIAVLLILQLAVVAVALQCNANFAYFAAVFEATSFNFLF
TTPRYSLQMFNLEDILNLTVFLLVALTTSKLAELYRRQQAALEQAQLRNSILLSVSHDLRTPLSTIIGTLTTLKEYMPKL
SASQKTELIDSAAAESHRLHQYIENLLQATKLQHGALKFSLSEDAMMNVLHQAIGRFPAAQPRIVIDSEAELPPLMISSS
LIEQAIFNVLDNALRYSPLDKPVTVKAYQQGDMLRLDIQDEGVGIAAAEAQAIFELFYRQHPSTDGGAGLGLAVAKGIIT
AHGGQISAEPVAKGSLIRIALPIKKGEQ

Sequences:

>Translated_348_residues
MTSSIAAPMTQYWRSHPTFFTGTVLVIAIFSSAFIDYFAGSTIAVLLILQLAVVAVALQCNANFAYFAAVFEATSFNFLF
TTPRYSLQMFNLEDILNLTVFLLVALTTSKLAELYRRQQAALEQAQLRNSILLSVSHDLRTPLSTIIGTLTTLKEYMPKL
SASQKTELIDSAAAESHRLHQYIENLLQATKLQHGALKFSLSEDAMMNVLHQAIGRFPAAQPRIVIDSEAELPPLMISSS
LIEQAIFNVLDNALRYSPLDKPVTVKAYQQGDMLRLDIQDEGVGIAAAEAQAIFELFYRQHPSTDGGAGLGLAVAKGIIT
AHGGQISAEPVAKGSLIRIALPIKKGEQ
>Mature_347_residues
TSSIAAPMTQYWRSHPTFFTGTVLVIAIFSSAFIDYFAGSTIAVLLILQLAVVAVALQCNANFAYFAAVFEATSFNFLFT
TPRYSLQMFNLEDILNLTVFLLVALTTSKLAELYRRQQAALEQAQLRNSILLSVSHDLRTPLSTIIGTLTTLKEYMPKLS
ASQKTELIDSAAAESHRLHQYIENLLQATKLQHGALKFSLSEDAMMNVLHQAIGRFPAAQPRIVIDSEAELPPLMISSSL
IEQAIFNVLDNALRYSPLDKPVTVKAYQQGDMLRLDIQDEGVGIAAAEAQAIFELFYRQHPSTDGGAGLGLAVAKGIITA
HGGQISAEPVAKGSLIRIALPIKKGEQ

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=261, Percent_Identity=31.4176245210728, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=28.4584980237154, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=277, Percent_Identity=28.8808664259928, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=263, Percent_Identity=26.9961977186312, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=28, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=26.457399103139, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=31.2236286919831, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=27.3858921161826, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=211, Percent_Identity=29.3838862559242, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=25.8771929824561, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=24.8927038626609, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=24.3697478991597, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789808, Length=225, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790300, Length=259, Percent_Identity=24.3243243243243, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1790551, Length=247, Percent_Identity=26.7206477732794, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37988; Mature: 37857

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSIAAPMTQYWRSHPTFFTGTVLVIAIFSSAFIDYFAGSTIAVLLILQLAVVAVALQC
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
NANFAYFAAVFEATSFNFLFTTPRYSLQMFNLEDILNLTVFLLVALTTSKLAELYRRQQA
CCCHHHHHHHHHHCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEQAQLRNSILLSVSHDLRTPLSTIIGTLTTLKEYMPKLSASQKTELIDSAAAESHRLH
HHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QYIENLLQATKLQHGALKFSLSEDAMMNVLHQAIGRFPAAQPRIVIDSEAELPPLMISSS
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHH
LIEQAIFNVLDNALRYSPLDKPVTVKAYQQGDMLRLDIQDEGVGIAAAEAQAIFELFYRQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
HPSTDGGAGLGLAVAKGIITAHGGQISAEPVAKGSLIRIALPIKKGEQ
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TSSIAAPMTQYWRSHPTFFTGTVLVIAIFSSAFIDYFAGSTIAVLLILQLAVVAVALQC
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
NANFAYFAAVFEATSFNFLFTTPRYSLQMFNLEDILNLTVFLLVALTTSKLAELYRRQQA
CCCHHHHHHHHHHCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEQAQLRNSILLSVSHDLRTPLSTIIGTLTTLKEYMPKLSASQKTELIDSAAAESHRLH
HHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QYIENLLQATKLQHGALKFSLSEDAMMNVLHQAIGRFPAAQPRIVIDSEAELPPLMISSS
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHH
LIEQAIFNVLDNALRYSPLDKPVTVKAYQQGDMLRLDIQDEGVGIAAAEAQAIFELFYRQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
HPSTDGGAGLGLAVAKGIITAHGGQISAEPVAKGSLIRIALPIKKGEQ
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9226259; 11466286 [H]