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The map label for this gene is spoIIIJ

Identifier: 16081156

GI number: 16081156

Start: 4213823

End: 4214608

Strand: Reverse

Name: spoIIIJ

Synonym: BSU41040

Alternate gene names: 16081156

Gene position: 4214608-4213823 (Counterclockwise)

Preceding gene: 16081157

Following gene: 16081155

Centisome position: 99.98

GC content: 40.71

Gene sequence:

>786_bases
ATGTTGTTGAAAAGGAGAATAGGGTTGCTATTAAGTATGGTTGGCGTATTCATGCTTTTGGCTGGATGCTCGAGTGTGAA
AGAGCCGATCACTGCAGATAGTCCGCATTTCTGGGACAAGTACGTAGTATATCCATTGTCTGAGCTCATTACGTATGTAG
CGAAATTGACGGGAGATAACTACGGGCTTTCAATTATTCTAGTTACCATTTTAATTCGTTTATTAATTTTACCGCTGATG
ATTAAGCAGCTGAGAAGTTCGAAAGCGATGCAGGCTTTACAGCCGGAAATGCAAAAGCTTAAAGAAAAATACAGCTCAAA
GGATCAAAAAACGCAGCAAAAGCTTCAACAGGAAACAATGGCTTTATTCCAAAAGCATGGTGTCAATCCATTGGCGGGAT
GTTTCCCGATTTTGATCCAGATGCCGATTTTAATTGGATTCTATCATGCGATCATGAGAACCCAGGCGATTTCAGAGCAT
AGCTTCTTATGGTTTGACTTAGGAGAAAAAGATCCTTACTATATTCTTCCTATCGTTGCCGGTGTCGCTACATTTGTTCA
GCAAAAACTGATGATGGCTGGCAATGCGCAGCAAAATCCGCAAATGGCGATGATGCTTTGGATTATGCCAATTATGATTA
TCGTATTTGCGATCAACTTCCCGGCGGCTCTTTCTCTTTATTGGGTAGTTGGTAACTTGTTTATGATTGCGCAAACTTTC
CTCATTAAAGGACCTGATATTAAAAAAAATCCTGAGCCGCAAAAAGCCGGAGGAAAGAAAAAGTGA

Upstream 100 bases:

>100_bases
TGGTTGATCAGAAAAAGACACCATTTAAAACTGAAAGATGCTAAAATACATACAAGTATGCTTTGCAATAAAAGAGTGTA
AAGATTAATTATAGGAGGAA

Downstream 100 bases:

>100_bases
GGAATGTGACTGCTGCAGGGCGAAATGTCGATGAAGCAGTACAGTCCGGATTGCAAGAGTTGGGATTAACGAAGGATAAG
GTAGAAATTACTGTTATTGA

Product: OxaA-like protein precursor

Products: NA

Alternate protein names: Stage III sporulation protein J

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLLKRRIGLLLSMVGVFMLLAGCSSVKEPITADSPHFWDKYVVYPLSELITYVAKLTGDNYGLSIILVTILIRLLILPLM
IKQLRSSKAMQALQPEMQKLKEKYSSKDQKTQQKLQQETMALFQKHGVNPLAGCFPILIQMPILIGFYHAIMRTQAISEH
SFLWFDLGEKDPYYILPIVAGVATFVQQKLMMAGNAQQNPQMAMMLWIMPIMIIVFAINFPAALSLYWVVGNLFMIAQTF
LIKGPDIKKNPEPQKAGGKKK

Sequences:

>Translated_261_residues
MLLKRRIGLLLSMVGVFMLLAGCSSVKEPITADSPHFWDKYVVYPLSELITYVAKLTGDNYGLSIILVTILIRLLILPLM
IKQLRSSKAMQALQPEMQKLKEKYSSKDQKTQQKLQQETMALFQKHGVNPLAGCFPILIQMPILIGFYHAIMRTQAISEH
SFLWFDLGEKDPYYILPIVAGVATFVQQKLMMAGNAQQNPQMAMMLWIMPIMIIVFAINFPAALSLYWVVGNLFMIAQTF
LIKGPDIKKNPEPQKAGGKKK
>Mature_261_residues
MLLKRRIGLLLSMVGVFMLLAGCSSVKEPITADSPHFWDKYVVYPLSELITYVAKLTGDNYGLSIILVTILIRLLILPLM
IKQLRSSKAMQALQPEMQKLKEKYSSKDQKTQQKLQQETMALFQKHGVNPLAGCFPILIQMPILIGFYHAIMRTQAISEH
SFLWFDLGEKDPYYILPIVAGVATFVQQKLMMAGNAQQNPQMAMMLWIMPIMIIVFAINFPAALSLYWVVGNLFMIAQTF
LIKGPDIKKNPEPQKAGGKKK

Specific function: Membrane protein required for the insertion of membrane proteins into the membrane. Also involved in protein secretion processes. Essential for sporulation by activating spoIIIG/sigG in the prespore. It has an overlapping, through partly distinct, functio

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI223718097, Length=198, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1790140, Length=227, Percent_Identity=36.5638766519824, Blast_Score=144, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6321002, Length=210, Percent_Identity=27.1428571428571, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24662345, Length=199, Percent_Identity=27.1356783919598, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21356443, Length=199, Percent_Identity=27.1356783919598, Blast_Score=91, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA1_BACSU (Q01625)

Other databases:

- EMBL:   Z14225
- EMBL:   X62539
- EMBL:   D26185
- EMBL:   AL009126
- PIR:   I40437
- RefSeq:   NP_391984.1
- EnsemblBacteria:   EBBACT00000002955
- GeneID:   937934
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU41040
- NMPDR:   fig|224308.1.peg.4110
- GenoList:   BSU41040
- GeneTree:   EBGT00050000002639
- HOGENOM:   HBG560622
- OMA:   HSFLWFD
- ProtClustDB:   PRK02944
- BioCyc:   BSUB:BSU41040-MONOMER
- HAMAP:   MF_01811
- InterPro:   IPR001708
- InterPro:   IPR023060
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 29522; Mature: 29522

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x134fbd80)-; HASH(0x12f68b54)-; HASH(0x13c45d50)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKRRIGLLLSMVGVFMLLAGCSSVKEPITADSPHFWDKYVVYPLSELITYVAKLTGDN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
YGLSIILVTILIRLLILPLMIKQLRSSKAMQALQPEMQKLKEKYSSKDQKTQQKLQQETM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ALFQKHGVNPLAGCFPILIQMPILIGFYHAIMRTQAISEHSFLWFDLGEKDPYYILPIVA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHH
GVATFVQQKLMMAGNAQQNPQMAMMLWIMPIMIIVFAINFPAALSLYWVVGNLFMIAQTF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LIKGPDIKKNPEPQKAGGKKK
HHCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MLLKRRIGLLLSMVGVFMLLAGCSSVKEPITADSPHFWDKYVVYPLSELITYVAKLTGDN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
YGLSIILVTILIRLLILPLMIKQLRSSKAMQALQPEMQKLKEKYSSKDQKTQQKLQQETM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ALFQKHGVNPLAGCFPILIQMPILIGFYHAIMRTQAISEHSFLWFDLGEKDPYYILPIVA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHH
GVATFVQQKLMMAGNAQQNPQMAMMLWIMPIMIIVFAINFPAALSLYWVVGNLFMIAQTF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LIKGPDIKKNPEPQKAGGKKK
HHCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1487728; 1552862; 7584024; 9384377; 11889108; 12586834; 12813085