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The map label for this gene is yxdK

Identifier: 16081016

GI number: 16081016

Start: 4071310

End: 4072287

Strand: Reverse

Name: yxdK

Synonym: BSU39650

Alternate gene names: 16081016

Gene position: 4072287-4071310 (Counterclockwise)

Preceding gene: 16081017

Following gene: 255767849

Centisome position: 96.6

GC content: 46.11

Gene sequence:

>978_bases
ATGAAGCTGTTTCTCCGGTCTCATGCAGTGCTGATTCTGCTTTTTCTCCTTCAAGGGCTGTTTGTCTTCTTTTATTACTG
GTTTGCGGGTCTTCATTCTTTTTCTCACTTGTTTTACATATTGGGCGTGCAGCTTCTTATTTTGGCGGGCTATCTTGCCT
ATCGCTGGTACAAAGACCGCGGCGTGTATCATTGGCTCAGCTCGGGGCAGGAAGGGACGGATATCCCGTATCTCGGTTCT
TCAGTGTTCTGTTCAGAGCTGTATGAAAAGCAGATGGAGCTGATCCGGCTGCAGCACCAGAAGCTCCATGAGACCGAAGC
CAAGCTTGACGCGCGGGTGACGTATATGAATCAATGGGTGCACCAAGTAAAGACGCCGCTGTCGGTCATTAATTTAATCA
TTCAAGAAGAGGATGAGCCCGTTTTTGAACAAATCAAAAAAGAAGTCCGGCAGATTGAATTCGGGCTGGAGACGCTTCTT
TATTCTTCAAGGCTCGACCTGTTTGAACGGGATTTTAAAATCGAAGCGGTTTCCCTGTCCGAGCTTCTCCAATCAGTTAT
TCAAAGCTATAAACGATTTTTTATTCAATATCGCGTTTATCCGAAAATGAACGTTTGCGATGATCATCAGATTTACACCG
ATGCCAAATGGCTCAAATTTGCGATTGGCCAAGTGGTCACAAATGCGGTCAAGTATTCAGCGGGCAAGAGTGACAGACTT
GAGCTGAATGTCTTCTGCGATGAAGACAGGACGGTGCTTGAAGTCAAAGATTACGGTGTCGGGATTCCCTCACAAGACAT
CAAGCGGGTGTTTGACCCTTATTACACGGGTGAAAACGGGCGGCGTTTCCAAGAATCTACGGGAATCGGCCTCCATCTCG
TCAAAGAAATTACAGATAAGCTCAATCATACGGTGGACATCAGCTCGTCTCCCGGTGAAGGGACATCAGTTCGATTTTCA
TTTCTTACAAAAATGTAA

Upstream 100 bases:

>100_bases
ACGTGTATATCACGCGGCTCAGAAAAAAACTGCGGGAGCTGAATGCGCCTGTTTCTATTGAAGCGGTGCGGGGCGAAGGC
TACCAGCTGAGGGCGCAGTC

Downstream 100 bases:

>100_bases
GGCTGCGTTAAGAAAACAACATAGCCCGCTTTGTTTCCCCTTGATAACATGGATTTATGTCAAGGGGATTTTTATGTTGA
ACGTCCCGGCACTACATGAA

Product: two-component sensor histidine kinase YxdJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MKLFLRSHAVLILLFLLQGLFVFFYYWFAGLHSFSHLFYILGVQLLILAGYLAYRWYKDRGVYHWLSSGQEGTDIPYLGS
SVFCSELYEKQMELIRLQHQKLHETEAKLDARVTYMNQWVHQVKTPLSVINLIIQEEDEPVFEQIKKEVRQIEFGLETLL
YSSRLDLFERDFKIEAVSLSELLQSVIQSYKRFFIQYRVYPKMNVCDDHQIYTDAKWLKFAIGQVVTNAVKYSAGKSDRL
ELNVFCDEDRTVLEVKDYGVGIPSQDIKRVFDPYYTGENGRRFQESTGIGLHLVKEITDKLNHTVDISSSPGEGTSVRFS
FLTKM

Sequences:

>Translated_325_residues
MKLFLRSHAVLILLFLLQGLFVFFYYWFAGLHSFSHLFYILGVQLLILAGYLAYRWYKDRGVYHWLSSGQEGTDIPYLGS
SVFCSELYEKQMELIRLQHQKLHETEAKLDARVTYMNQWVHQVKTPLSVINLIIQEEDEPVFEQIKKEVRQIEFGLETLL
YSSRLDLFERDFKIEAVSLSELLQSVIQSYKRFFIQYRVYPKMNVCDDHQIYTDAKWLKFAIGQVVTNAVKYSAGKSDRL
ELNVFCDEDRTVLEVKDYGVGIPSQDIKRVFDPYYTGENGRRFQESTGIGLHLVKEITDKLNHTVDISSSPGEGTSVRFS
FLTKM
>Mature_325_residues
MKLFLRSHAVLILLFLLQGLFVFFYYWFAGLHSFSHLFYILGVQLLILAGYLAYRWYKDRGVYHWLSSGQEGTDIPYLGS
SVFCSELYEKQMELIRLQHQKLHETEAKLDARVTYMNQWVHQVKTPLSVINLIIQEEDEPVFEQIKKEVRQIEFGLETLL
YSSRLDLFERDFKIEAVSLSELLQSVIQSYKRFFIQYRVYPKMNVCDDHQIYTDAKWLKFAIGQVVTNAVKYSAGKSDRL
ELNVFCDEDRTVLEVKDYGVGIPSQDIKRVFDPYYTGENGRRFQESTGIGLHLVKEITDKLNHTVDISSSPGEGTSVRFS
FLTKM

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1789808, Length=296, Percent_Identity=24.3243243243243, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=287, Percent_Identity=25.4355400696864, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YXDK_BACSU (P42422)

Other databases:

- EMBL:   D14399
- EMBL:   AL009126
- EMBL:   D45912
- PIR:   H70073
- RefSeq:   NP_391844.1
- ProteinModelPortal:   P42422
- SMR:   P42422
- EnsemblBacteria:   EBBACT00000001014
- GeneID:   937487
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU39650
- NMPDR:   fig|224308.1.peg.3970
- GenoList:   BSU39650
- GeneTree:   EBGT00050000000011
- HOGENOM:   HBG698185
- OMA:   ANINTQI
- ProtClustDB:   CLSK888171
- BioCyc:   BSUB:BSU39650-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF02518 HATPase_c; SSF55874 ATP_bd_ATPase

EC number: =2.7.13.3

Molecular weight: Translated: 37989; Mature: 37989

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1232d178)-; HASH(0x136eb258)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCEEECCCCCCCCCEEEHEEECCH
>Mature Secondary Structure
MKLFLRSHAVLILLFLLQGLFVFFYYWFAGLHSFSHLFYILGVQLLILAGYLAYRWYKDR
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVYHWLSSGQEGTDIPYLGSSVFCSELYEKQMELIRLQHQKLHETEAKLDARVTYMNQWV
CHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQVKTPLSVINLIIQEEDEPVFEQIKKEVRQIEFGLETLLYSSRLDLFERDFKIEAVSLS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHH
ELLQSVIQSYKRFFIQYRVYPKMNVCDDHQIYTDAKWLKFAIGQVVTNAVKYSAGKSDRL
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
ELNVFCDEDRTVLEVKDYGVGIPSQDIKRVFDPYYTGENGRRFQESTGIGLHLVKEITDK
EEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHHHH
LNHTVDISSSPGEGTSVRFSFLTKM
HCCEEECCCCCCCCCEEEHEEECCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804