Click here to switch to the map view.

The map label for this gene is ywaC

Identifier: 16080899

GI number: 16080899

Start: 3949952

End: 3950584

Strand: Reverse

Name: ywaC

Synonym: BSU38480

Alternate gene names: 16080899

Gene position: 3950584-3949952 (Counterclockwise)

Preceding gene: 16080900

Following gene: 16080895

Centisome position: 93.71

GC content: 38.55

Gene sequence:

>633_bases
ATGGATTTATCTGTAACACATATGGACGATTTAAAAACAGTAATGGAAGATTGGAAAAATGAGTTATTAGTTTATAAATT
TGCGCTAGATGCGCTCGATACAAAGTTCTCAATTATCAGCCAGGAATATAACCTCATTCACGGACACAACCCGATTGAAC
ATACAAAATCCCGTGTAAAAAGCTTTGAAAGCATCGTGAATAAGTTAATGAGAAAGGGCTGTGAGATTACGACGAAGGAA
ATGAAGGAGCATATTCACGACATTGCCGGCGTGCGCATCATCTGTTCCTTTATTTCTGACATTTATAATGTCGTGAATGT
GTTGAAGCAGCATGAAGATTTGAGAATCGTAAAGGTAAAGGATTATATCCAGACACCCAAACCGAATGGCTATCGAAGCC
TGCATTTAATCATTGAGATGCCTGTGAATTTAACGAACCGTGTGGAATACGTCAAAGCAGAAATTCAAATCCGGACAATC
GCGATGGATTTCTGGGCGAGCCTTGAACATAAAATTTATTATAAATTGAACAATGACGTTCCTAAGCAATTAACAGATGA
GCTGAAAGAAGCCGCGGAGATTGCCCATTACCTAGATGAGAAAATGCTGGGGATTAAGAAAGAAGTGGATTAA

Upstream 100 bases:

>100_bases
ATCGACCGCATTTTGTAAAAAAATTCATAGAACCTTGCAGCAGACAGGGACGTCTAGTACATGGACAGCGGATAAAGTTC
CGTTAAAGGAGATGACGAAC

Downstream 100 bases:

>100_bases
AAAAGACGGCACCCAAGTGCCGTCTTTTTTTATTTGATATCTTCAAAAATGTCAGATGCTTTCGCCTTCATTTGTTTCTT
AATGGTTTTCGGTTTCTTCT

Product: (p)ppGpp synthetase

Products: NA

Alternate protein names: (p)ppGpp synthase ywaC; Small alarmone synthase 2; SAS 2

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MDLSVTHMDDLKTVMEDWKNELLVYKFALDALDTKFSIISQEYNLIHGHNPIEHTKSRVKSFESIVNKLMRKGCEITTKE
MKEHIHDIAGVRIICSFISDIYNVVNVLKQHEDLRIVKVKDYIQTPKPNGYRSLHLIIEMPVNLTNRVEYVKAEIQIRTI
AMDFWASLEHKIYYKLNNDVPKQLTDELKEAAEIAHYLDEKMLGIKKEVD

Sequences:

>Translated_210_residues
MDLSVTHMDDLKTVMEDWKNELLVYKFALDALDTKFSIISQEYNLIHGHNPIEHTKSRVKSFESIVNKLMRKGCEITTKE
MKEHIHDIAGVRIICSFISDIYNVVNVLKQHEDLRIVKVKDYIQTPKPNGYRSLHLIIEMPVNLTNRVEYVKAEIQIRTI
AMDFWASLEHKIYYKLNNDVPKQLTDELKEAAEIAHYLDEKMLGIKKEVD
>Mature_210_residues
MDLSVTHMDDLKTVMEDWKNELLVYKFALDALDTKFSIISQEYNLIHGHNPIEHTKSRVKSFESIVNKLMRKGCEITTKE
MKEHIHDIAGVRIICSFISDIYNVVNVLKQHEDLRIVKVKDYIQTPKPNGYRSLHLIIEMPVNLTNRVEYVKAEIQIRTI
AMDFWASLEHKIYYKLNNDVPKQLTDELKEAAEIAHYLDEKMLGIKKEVD

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in respo

COG id: COG2357

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the relA/spoT family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YWAC_BACSU (P39583)

Other databases:

- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S39662
- RefSeq:   NP_391727.1
- ProteinModelPortal:   P39583
- SMR:   P39583
- EnsemblBacteria:   EBBACT00000000388
- GeneID:   937355
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38480
- NMPDR:   fig|224308.1.peg.3853
- GenoList:   BSU38480
- GeneTree:   EBGT00050000001680
- HOGENOM:   HBG516408
- OMA:   GTKDVFA
- ProtClustDB:   CLSK2502636
- BioCyc:   BSUB:BSU38480-MONOMER
- InterPro:   IPR007685
- SMART:   SM00954

Pfam domain/function: PF04607 RelA_SpoT

EC number: =2.7.6.5

Molecular weight: Translated: 24600; Mature: 24600

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSVTHMDDLKTVMEDWKNELLVYKFALDALDTKFSIISQEYNLIHGHNPIEHTKSRVK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SFESIVNKLMRKGCEITTKEMKEHIHDIAGVRIICSFISDIYNVVNVLKQHEDLRIVKVK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
DYIQTPKPNGYRSLHLIIEMPVNLTNRVEYVKAEIQIRTIAMDFWASLEHKIYYKLNNDV
HHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
PKQLTDELKEAAEIAHYLDEKMLGIKKEVD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLSVTHMDDLKTVMEDWKNELLVYKFALDALDTKFSIISQEYNLIHGHNPIEHTKSRVK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SFESIVNKLMRKGCEITTKEMKEHIHDIAGVRIICSFISDIYNVVNVLKQHEDLRIVKVK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
DYIQTPKPNGYRSLHLIIEMPVNLTNRVEYVKAEIQIRTIAMDFWASLEHKIYYKLNNDV
HHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
PKQLTDELKEAAEIAHYLDEKMLGIKKEVD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377