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The map label for this gene is ywbA

Identifier: 16080890

GI number: 16080890

Start: 3938307

End: 3939641

Strand: Reverse

Name: ywbA

Synonym: BSU38390

Alternate gene names: 16080890

Gene position: 3939641-3938307 (Counterclockwise)

Preceding gene: 16080894

Following gene: 16080889

Centisome position: 93.45

GC content: 52.36

Gene sequence:

>1335_bases
ATGAGCACATTCACTCGGGTGATGGAGGAAAAAATAATGCCTGTCGCCGGGAAAATTGCCGGGCAGCGGCATCTCAGCGC
TTTGCGTGACGGAATTATCCTGACCATGCCGCTGATTATTATCGGGTCTGTCTTCTTGATTTTAACGAGCTTGCCGATTC
CGGGGTATGCTGATTTCATGGCGAGTGTGTTTGGGAACGAGTGGGCCGATAAGCTCGGATATCCTGTTAACGCTTCGTTT
GATATTATGGCGATGATTGCCGCTTTTGGGATCGCCTATCGGCTGGCAGAAAGCTATGGTGTCGATGCCCTTTCTGCCGG
AGCGATTTCAATTGCCGCATTTCTGCTGGCAACACCGTTTGAGGTGCCGTTTACACCGCATGGCTCAACGGAGTCCATCA
TGGTAGGGGGCGGAATCCCGATCACGCTGCTCGGCAGCAAGGGCTTATTTGTCGCCATGCTGATCGCCTTGTTTTCAACC
GAAATCTATCGGTACATTATTCAAAAAAATATCGTCTTCAAAATGCCAGACGGTGTGCCGCCTGCGGTAAGCAAATCATT
TGTCGCGCTGATTCCCGGCTTTATCATTGTGCTTCTCGTATGGCTGGCGCGTCTTCTGATTGAAATGACACCTTTTCAGA
GTCTGCACAATGTCGTAGGAGACCTGCTTGGCACACCGCTTTCCATCCTTGGCGGCAGTCTCGGCGGAAGCCTGATCGCT
GAATTTGTGCAGATGCTGCTTTGGTCGTGCGGGATTCACGGGGCTTCCATCATTGGCGGAATCATGGCGCCGATTTGGTA
CGGCGCGATGGATGCCAACCGTCTCGCCTTCCAAGCAGGCGAGGCGCTGCCGAGTATTTTTACGACTCAGTTTTTTCAAA
TTTGGATCAATGTCGGCGGAAGCGGGGCGACGCTGGCGCTTGTCCTGACGATGCTTGTGCGCTCCCGCAGCAAACAAATG
AAGCAGCTTGGACGATTAGGAATCGGCCCTGCGCTATTTAATATCAACGAGCCGATCATTTTCGGCATGCCGATTGTCAT
GAATCCCCTCCTTATTGTCCCATTTATCATCGCACCGCTCCTCACGATTACCGCGACTTATATCGGCATGAGCACCGGGC
TGGTGGCAAGACCGGCCGGAATCGCGGTGCCATGGACGATGCCGCCGCTCATATCAGGTTACCTGGCGACAGGCGGAAAG
GTGTCGGGCGCAGTTATGCAGCTGGTAAATCTGCTGATCACCTGTGCTATCTACTATCCGTTTTTCAGAATATGGGATCA
TCAAAAATGGCGGGAAGAGAGTGCGGTTGAATCTGGGGATAAAAATGTGATGTGA

Upstream 100 bases:

>100_bases
GAGGAAATTTTCCAAATGAATTTGTAAGCGTTTTCAAAATAAGATAAAGAAAACATTGCGGAGGTTGTTCACAAAGCAAT
GAGAAAAGGGGGTTTTTAAG

Downstream 100 bases:

>100_bases
TAGATGATCAGCCTGTCATAGGGCTGATCATCTCTTTCAAACGAAAGGAATGTTAGAATATGTAAAGGAGGTGCGCATGC
TAGATTATATATGGTTAGAT

Product: phosphotransferase system enzyme IIC permease

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Putative PTS system EIIC component

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSTFTRVMEEKIMPVAGKIAGQRHLSALRDGIILTMPLIIIGSVFLILTSLPIPGYADFMASVFGNEWADKLGYPVNASF
DIMAMIAAFGIAYRLAESYGVDALSAGAISIAAFLLATPFEVPFTPHGSTESIMVGGGIPITLLGSKGLFVAMLIALFST
EIYRYIIQKNIVFKMPDGVPPAVSKSFVALIPGFIIVLLVWLARLLIEMTPFQSLHNVVGDLLGTPLSILGGSLGGSLIA
EFVQMLLWSCGIHGASIIGGIMAPIWYGAMDANRLAFQAGEALPSIFTTQFFQIWINVGGSGATLALVLTMLVRSRSKQM
KQLGRLGIGPALFNINEPIIFGMPIVMNPLLIVPFIIAPLLTITATYIGMSTGLVARPAGIAVPWTMPPLISGYLATGGK
VSGAVMQLVNLLITCAIYYPFFRIWDHQKWREESAVESGDKNVM

Sequences:

>Translated_444_residues
MSTFTRVMEEKIMPVAGKIAGQRHLSALRDGIILTMPLIIIGSVFLILTSLPIPGYADFMASVFGNEWADKLGYPVNASF
DIMAMIAAFGIAYRLAESYGVDALSAGAISIAAFLLATPFEVPFTPHGSTESIMVGGGIPITLLGSKGLFVAMLIALFST
EIYRYIIQKNIVFKMPDGVPPAVSKSFVALIPGFIIVLLVWLARLLIEMTPFQSLHNVVGDLLGTPLSILGGSLGGSLIA
EFVQMLLWSCGIHGASIIGGIMAPIWYGAMDANRLAFQAGEALPSIFTTQFFQIWINVGGSGATLALVLTMLVRSRSKQM
KQLGRLGIGPALFNINEPIIFGMPIVMNPLLIVPFIIAPLLTITATYIGMSTGLVARPAGIAVPWTMPPLISGYLATGGK
VSGAVMQLVNLLITCAIYYPFFRIWDHQKWREESAVESGDKNVM
>Mature_443_residues
STFTRVMEEKIMPVAGKIAGQRHLSALRDGIILTMPLIIIGSVFLILTSLPIPGYADFMASVFGNEWADKLGYPVNASFD
IMAMIAAFGIAYRLAESYGVDALSAGAISIAAFLLATPFEVPFTPHGSTESIMVGGGIPITLLGSKGLFVAMLIALFSTE
IYRYIIQKNIVFKMPDGVPPAVSKSFVALIPGFIIVLLVWLARLLIEMTPFQSLHNVVGDLLGTPLSILGGSLGGSLIAE
FVQMLLWSCGIHGASIIGGIMAPIWYGAMDANRLAFQAGEALPSIFTTQFFQIWINVGGSGATLALVLTMLVRSRSKQMK
QLGRLGIGPALFNINEPIIFGMPIVMNPLLIVPFIIAPLLTITATYIGMSTGLVARPAGIAVPWTMPPLISGYLATGGKV
SGAVMQLVNLLITCAIYYPFFRIWDHQKWREESAVESGDKNVM

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain

Homologues:

Organism=Escherichia coli, GI1788032, Length=464, Percent_Identity=33.8362068965517, Blast_Score=214, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YWBA_BACSU (P39584)

Other databases:

- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S39671
- RefSeq:   NP_391718.1
- ProteinModelPortal:   P39584
- EnsemblBacteria:   EBBACT00000000877
- GeneID:   937331
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38390
- NMPDR:   fig|224308.1.peg.3844
- GenoList:   BSU38390
- GeneTree:   EBGT00050000001946
- HOGENOM:   HBG532931
- PhylomeDB:   P39584
- ProtClustDB:   CLSK888108
- BioCyc:   BSUB:BSU38390-MONOMER
- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501
- TIGRFAMs:   TIGR00359
- TIGRFAMs:   TIGR00410

Pfam domain/function: PF02378 PTS_EIIC

EC number: NA

Molecular weight: Translated: 47649; Mature: 47517

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13353494)-; HASH(0x121fbc6c)-; HASH(0x1301f158)-; HASH(0x12781c74)-; HASH(0x131f372c)-; HASH(0x13390a38)-; HASH(0x12ff298c)-; HASH(0x12be9b70)-; HASH(0x12166b9c)-; HASH(0x122dc1dc)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFTRVMEEKIMPVAGKIAGQRHLSALRDGIILTMPLIIIGSVFLILTSLPIPGYADFM
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ASVFGNEWADKLGYPVNASFDIMAMIAAFGIAYRLAESYGVDALSAGAISIAAFLLATPF
HHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
EVPFTPHGSTESIMVGGGIPITLLGSKGLFVAMLIALFSTEIYRYIIQKNIVFKMPDGVP
CCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
PAVSKSFVALIPGFIIVLLVWLARLLIEMTPFQSLHNVVGDLLGTPLSILGGSLGGSLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCCCCHHHHH
EFVQMLLWSCGIHGASIIGGIMAPIWYGAMDANRLAFQAGEALPSIFTTQFFQIWINVGG
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGATLALVLTMLVRSRSKQMKQLGRLGIGPALFNINEPIIFGMPIVMNPLLIVPFIIAPL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEECCHHHHHHHHHHHHHHHHH
LTITATYIGMSTGLVARPAGIAVPWTMPPLISGYLATGGKVSGAVMQLVNLLITCAIYYP
HHHHHHHHHHHCCCEECCCCEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FFRIWDHQKWREESAVESGDKNVM
HHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
STFTRVMEEKIMPVAGKIAGQRHLSALRDGIILTMPLIIIGSVFLILTSLPIPGYADFM
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ASVFGNEWADKLGYPVNASFDIMAMIAAFGIAYRLAESYGVDALSAGAISIAAFLLATPF
HHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
EVPFTPHGSTESIMVGGGIPITLLGSKGLFVAMLIALFSTEIYRYIIQKNIVFKMPDGVP
CCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
PAVSKSFVALIPGFIIVLLVWLARLLIEMTPFQSLHNVVGDLLGTPLSILGGSLGGSLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCCCCHHHHH
EFVQMLLWSCGIHGASIIGGIMAPIWYGAMDANRLAFQAGEALPSIFTTQFFQIWINVGG
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGATLALVLTMLVRSRSKQMKQLGRLGIGPALFNINEPIIFGMPIVMNPLLIVPFIIAPL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEECCHHHHHHHHHHHHHHHHH
LTITATYIGMSTGLVARPAGIAVPWTMPPLISGYLATGGKVSGAVMQLVNLLITCAIYYP
HHHHHHHHHHHCCCEECCCCEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FFRIWDHQKWREESAVESGDKNVM
HHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377