Click here to switch to the map view.

The map label for this gene is argS

Identifier: 16080786

GI number: 16080786

Start: 3833650

End: 3835320

Strand: Reverse

Name: argS

Synonym: BSU37330

Alternate gene names: 16080786

Gene position: 3835320-3833650 (Counterclockwise)

Preceding gene: 16080787

Following gene: 255767791

Centisome position: 90.98

GC content: 48.59

Gene sequence:

>1671_bases
ATGAACATTGCGGAACAAATGAAGGACGTGCTGAAAGAAGAAATCAAAGCGGCCGTTCTGAAAGCGGGACTGGCTGAAGA
AAGCCAGATTCCCAATGTTGTTTTAGAAACACCGAAAGATAAAACACACGGCGACTACTCAACGAATATGGCGATGCAGT
TGGCAAGAGTGGCAAAAAAAGCGCCGCGTCAAATCGCTGAAGAGATTGTCGCCCATTTTGATAAAGGGAAGGCTTCGATT
GAAAAACTGGATATCGCCGGCCCGGGTTTTATCAATTTCTATATGAACAATCAATATTTAACAAAGCTGATTCCGTCTGT
ACTGGAAGCAGGGGAAGCATACGGGGAAACGAACATCGGAAACGGTGAACGAGTTCAGGTAGAATTCGTATCAGCGAATC
CGACGGGAGACCTTCACCTCGGGCATGCGCGCGGGGCGGCTGTCGGCGATTCCTTGTGCAACGTGCTTTCAAAAGCGGGT
TACGATGTAAGCCGCGAATACTACATTAACGATGCGGGAAACCAAATCAACAATCTGGCGCTTTCTGTTGAAGTCCGTTA
CTTTGAAGCACTCGGATTGGAAAAACCGATGCCGGAGGATGGCTACCGCGGTGAGGATATCATTGCGATCGGAAAGCGTC
TCGCTGAGGAATACGGTGATCGTTTCGTTAACGAAGAGGAAAGTGAACGCCTCGCGTTTTTCCGTGAATACGGCCTGAAA
TACGAGCTGGAAAAGCTTCGCAAGGACTTGGAAAACTTCCGTGTGCCGTTTGATGTGTGGTATTCAGAAACTTCACTGTA
CCAAAATGGAAAAATCGACAAGGCGCTTGAAGCGCTCCGCGAAAAAGGCCACGTCTATGAAGAAGACGGCGCGACTTGGT
TCCGTTCCACGACTTTCGGCGATGATAAAGACCGCGTATTGATCAAGAAGGACGGCACGTACACGTACCTTCTTCCTGAT
ATCGCGTATCATAAGGACAAGCTTGACCGCGGCTTTGATAAGCTGATCAACGTTTGGGGCGCCGATCACCACGGCTACAT
CCCGCGTATGAAAGCGGCAATCGAAGCGCTGGGCTATGAAAAAGGAACGCTTGAAGTAGAAATCATTCAGCTCGTTCACC
TTTACAAAAACGGCGAGAAAATGAAAATGAGCAAACGGACCGGTAAAGCCGTAACGATGCGTGACCTGATTGAAGAAGTC
GGCTTGGATGCCGTGCGTTACTTCTTTGCAATGCGAAGTGCAGACACCCATATGGATTTTGACTTAGATCTTGCTGTATC
AACATCTAACGAAAACCCTGTGTATTATGCACAATACGCGCATGCCCGTATTTGCAGCATGCTTCGCCAAGGGGAAGAGC
AGGGGCTTAAACCGGCGGCAGATCTTGATTTCAGCCATATTCAATCAGAAAAAGAATACGATCTGCTGAAAACGATCGGC
GGCTTCCCAGAGGCAGTGGCGGAAGCAGCGGAAAAACGAATTCCGCACCGTGTCACTAACTATATTTATGATCTGGCTTC
TGCTCTGCACAGCTTCTACAACGCAGAGAAAGTCATCGACCCTGAAAATGAAGAGAAAAGCCGCGCGCGCCTGGCTTTAA
TGAAGGCAACGCAAATTACGCTGAACAATGCGCTTCAGCTGATCGGCGTATCGGCTCCGGAAAAAATGTAA

Upstream 100 bases:

>100_bases
AAGAAAAAGGCCGTATCAGCATCGCATATGACATGCATGTCGGAGACGAGCAGGAGCATTTACATAATATGACGATCACG
TATGAGGGAGGAACTCACGC

Downstream 100 bases:

>100_bases
TCACGATCAAAAGGACAAAGTCTTCGGGCTTTGTCCTTTTTTTATGAGAAAAACGTGTGATGTAATTCACAATCCTGTTT
GGCTAGTTTTTGTATGATAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGDYSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASI
EKLDIAGPGFINFYMNNQYLTKLIPSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAG
YDVSREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRFVNEEESERLAFFREYGLK
YELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALREKGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPD
IAYHKDKLDRGFDKLINVWGADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEEV
GLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKPAADLDFSHIQSEKEYDLLKTIG
GFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEKVIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM

Sequences:

>Translated_556_residues
MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGDYSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASI
EKLDIAGPGFINFYMNNQYLTKLIPSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAG
YDVSREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRFVNEEESERLAFFREYGLK
YELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALREKGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPD
IAYHKDKLDRGFDKLINVWGADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEEV
GLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKPAADLDFSHIQSEKEYDLLKTIG
GFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEKVIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM
>Mature_556_residues
MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGDYSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASI
EKLDIAGPGFINFYMNNQYLTKLIPSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAG
YDVSREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRFVNEEESERLAFFREYGLK
YELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALREKGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPD
IAYHKDKLDRGFDKLINVWGADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEEV
GLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKPAADLDFSHIQSEKEYDLLKTIG
GFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEKVIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=617, Percent_Identity=24.7974068071313, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI197100773, Length=609, Percent_Identity=21.5106732348112, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1788184, Length=607, Percent_Identity=27.5123558484349, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71985061, Length=594, Percent_Identity=25.9259259259259, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71985068, Length=560, Percent_Identity=26.25, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320548, Length=605, Percent_Identity=24.9586776859504, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321883, Length=598, Percent_Identity=22.5752508361204, Blast_Score=116, Evalue=8e-27,
Organism=Drosophila melanogaster, GI18859963, Length=620, Percent_Identity=24.8387096774194, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62724; Mature: 62724

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGDYSTNMAMQLARVAKK
CCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
APRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLIPSVLEAGEAYGETNIG
HHHHHHHHHHHHHCCCCHHHHHEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
NGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDVSREYYINDAGNQINNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEE
LSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRFVNEEESERLAFFREYGLK
EEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
YELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALREKGHVYEEDGATWFRSTTFG
HHHHHHHHHHHHCCCCCEEEECCHHHHCCCCHHHHHHHHHHCCCEEECCCCEEEEECCCC
DDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWGADHHGYIPRMKAAIEALGYE
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
KGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEEVGLDAVRYFFAMRSADTHMDF
CCCCHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCCE
DLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKPAADLDFSHIQSEKEYDLLKTIG
EEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHC
GFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEKVIDPENEEKSRARLALMKATQIT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
LNNALQLIGVSAPEKM
HHHHHHEEECCCCCCC
>Mature Secondary Structure
MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGDYSTNMAMQLARVAKK
CCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
APRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLIPSVLEAGEAYGETNIG
HHHHHHHHHHHHHCCCCHHHHHEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
NGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDVSREYYINDAGNQINNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEE
LSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRFVNEEESERLAFFREYGLK
EEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
YELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALREKGHVYEEDGATWFRSTTFG
HHHHHHHHHHHHCCCCCEEEECCHHHHCCCCHHHHHHHHHHCCCEEECCCCEEEEECCCC
DDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWGADHHGYIPRMKAAIEALGYE
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
KGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEEVGLDAVRYFFAMRSADTHMDF
CCCCHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCCE
DLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKPAADLDFSHIQSEKEYDLLKTIG
EEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHC
GFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEKVIDPENEEKSRARLALMKATQIT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
LNNALQLIGVSAPEKM
HHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA