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The map label for this gene is fnr

Identifier: 16080784

GI number: 16080784

Start: 3831512

End: 3832228

Strand: Reverse

Name: fnr

Synonym: BSU37310

Alternate gene names: 16080784

Gene position: 3832228-3831512 (Counterclockwise)

Preceding gene: 255767791

Following gene: 16080782

Centisome position: 90.91

GC content: 42.82

Gene sequence:

>717_bases
ATGAATTTTCTCTCTGTTCGACCATCTGATAGTGATCTTATATCCAGCGATCTGTATGAATTGCTGGAATCGATCAGCAC
GAAAAGAAAAATGGAAAAACACACGTATTTGTTTCGGGAAGGAATGGATGCAGAAGAGCTTTATCTGATTCAATCAGGAC
TCATTGAAATCGGCAAGCTGACATCTGACGGAAAAGACCTGACGCTTAGAATCTGCCAAAAGCATGATATCGTCGGAGAA
TTAACACTTTTCACTGAAGAACCAAGGTATATGCTCAGTGCAAAAGTACTAGAGGATGGCGAGGTGCTCGTCATTAATAA
AAATAAGCTGGAAAAAGAATTAATCCAAAACGGCGCTTTGACATTTGAGTTCATGAAATGGATGAGCACGCACCTCCGGA
AGATTCAGTCCAAAATCAGGGATCTGCTTCTTCATGGCAAAAAGGGGGCGCTCTATTCTACCCTTATCCGCTTATCAAAC
AGCTACGGAGTGGAGCGAAGCGACGGCATTCTGATTAACATTGTCCTGACAAATCAGGATTTGGCAAAGTTTTGCGCGGC
TGCACGGGAAAGCGTCAATCGTATGCTCGGAGATCTCCGCAAAAAAGGGGTTATTTCGATAGACGAATCCGGAAAAATTA
TTTTGCACAAGCGGGACTATTTACGATGTGAGATTGAGTGTGAAAATTGCCCGCTGGAGATTTGCAATATTGACTGA

Upstream 100 bases:

>100_bases
AACACTGGGGCATTCACAAGATTGTTAGTTTTTTCTCGATGGGTACAAATCAATTCACGTTACAATAAACACACAACGTG
ACTTTCTTCGAGGTGAGCTC

Downstream 100 bases:

>100_bases
AAAAAACAAGGACAGCGGTGTCCTTGTTTTTTTACCTTGTGATAAACAGGCACATGACGGCAAGAAAGAAGCAGGCATTC
ACGATTTCCAGAATGCCAAT

Product: FNR/CAP family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MNFLSVRPSDSDLISSDLYELLESISTKRKMEKHTYLFREGMDAEELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGE
LTLFTEEPRYMLSAKVLEDGEVLVINKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSN
SYGVERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLRCEIECENCPLEICNID

Sequences:

>Translated_238_residues
MNFLSVRPSDSDLISSDLYELLESISTKRKMEKHTYLFREGMDAEELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGE
LTLFTEEPRYMLSAKVLEDGEVLVINKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSN
SYGVERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLRCEIECENCPLEICNID
>Mature_238_residues
MNFLSVRPSDSDLISSDLYELLESISTKRKMEKHTYLFREGMDAEELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGE
LTLFTEEPRYMLSAKVLEDGEVLVINKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSN
SYGVERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLRCEIECENCPLEICNID

Specific function: It is involved in the activation of genes necessary for anaerobic respiration

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FNR_BACSU (P46908)

Other databases:

- EMBL:   Z49884
- EMBL:   AL009126
- PIR:   S60081
- RefSeq:   NP_391612.1
- ProteinModelPortal:   P46908
- SMR:   P46908
- EnsemblBacteria:   EBBACT00000000826
- GeneID:   937050
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU37310
- NMPDR:   fig|224308.1.peg.3738
- GenoList:   BSU37310
- GeneTree:   EBGT00070000031998
- HOGENOM:   HBG313735
- OMA:   TNEDIAG
- ProtClustDB:   CLSK872647
- BioCyc:   BSUB:BSU37310-MONOMER
- GO:   GO:0005737
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991
- Gene3D:   G3DSA:2.60.120.10
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00100
- SMART:   SM00419

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp; SSF51206 cNMP_binding

EC number: NA

Molecular weight: Translated: 27218; Mature: 27218

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50042 CNMP_BINDING_3; PS00042 HTH_CRP_1; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLSVRPSDSDLISSDLYELLESISTKRKMEKHTYLFREGMDAEELYLIQSGLIEIGKL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
TSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLVINKNKLEKELIQNGAL
CCCCCCCEEEEEHHCCCEEEEEEEECCCCCEEEEEEECCCCEEEEECCHHHHHHHHCCCH
TFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYGVERSDGILINIVLTNQD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCH
LAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLRCEIECENCPLEICNID
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCEEEEEEEECCCCEEEECCC
>Mature Secondary Structure
MNFLSVRPSDSDLISSDLYELLESISTKRKMEKHTYLFREGMDAEELYLIQSGLIEIGKL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
TSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLVINKNKLEKELIQNGAL
CCCCCCCEEEEEHHCCCEEEEEEEECCCCCEEEEEEECCCCEEEEECCHHHHHHHHCCCH
TFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYGVERSDGILINIVLTNQD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCH
LAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLRCEIECENCPLEICNID
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCEEEEEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377