Click here to switch to the map view.

The map label for this gene is ywqM

Identifier: 16080669

GI number: 16080669

Start: 3723454

End: 3724335

Strand: Direct

Name: ywqM

Synonym: BSU36160

Alternate gene names: 16080669

Gene position: 3723454-3724335 (Clockwise)

Preceding gene: 16080666

Following gene: 255767781

Centisome position: 88.33

GC content: 43.54

Gene sequence:

>882_bases
GTGGAATTGAAGCAGCTGATCACCTTTATTACGGCGGCTGAACATGTAAACTTCACCCTAACCGCCAAAATGCTTAATTA
TGCACAATCAAGCGTTACCTCTCAGATCAAATCACTTGAAGAAGAAATCGGAACGCCTTTATTTGAACGGCTCGGCAAGC
GGCTTATCTTGACAGAAGCAGGAAAAACGTTCAAATCTTATGCACAGAAGATCATTGCGTTAACAGAAGAAGCGAAAATG
GCCACAAATCAAGTAAGAGAAACAACCGGAACCTTAAAAATCGGGGCGACGGAAAGCCAGTGCACATACCGCCTGCCCCC
TATCATAAAAGAATTTAAACAGGCTTTTCCCCAAGTAAAGCTCATATTCAAACCATATATCTCCAATGAACAAGCGAAAG
AACAGCTCTTACAGGGCCAGCTTGATATCACCTTCATCTTGGATGTAAACCGGATGGAAGACGCACTGCACGTTGAATCT
TTGATTCAGGATGAGATCAAAATGGTGGCTGCTAATGACCATCCTTTTCCTGCGGATTTACCAGTAACATTGAAGGATCT
TCAAAACGAAACTCTTCTGCTGACAGAGGACGGCTGCTCGTACCGCACGCTCTTTGAGAACAATTTGCATGACTCCGGTA
TCTATCCTAACAAATTGGAATTCGTCAGCATAGAAGCCATCAAACAATGCGTGATGGCCGGACTTGGGATTGGAATCTTG
CCTGAAATGACAGTAAAAGATGATATTGCAGCAGGCCGGATGAAAGAACTCAATTGGCAGAGCGATTGCCCCGTTTTCAC
TCAATTAGCATGGCATAAGGACAAGTGGATGTCTGCGCCATTAAAGGCTTTTATCGATTTGACACGGAAAACATTCAAAT
AA

Upstream 100 bases:

>100_bases
CGAATGATTTTCTTCATCATATAATGGATTCATCAATCAATACAGATGATTATTTCGATTAATCCAATCGCTAAAACCGA
TTTAGAAAGGAAGAGAACAA

Downstream 100 bases:

>100_bases
AACCTCTCCACAAGGACGACAAGGTTTTTGAGACCAGGGCACACACATACAAAAAAAACACTTGATGACTTAGAGCCCCA
AGTGTTACACGTGATTTTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MELKQLITFITAAEHVNFTLTAKMLNYAQSSVTSQIKSLEEEIGTPLFERLGKRLILTEAGKTFKSYAQKIIALTEEAKM
ATNQVRETTGTLKIGATESQCTYRLPPIIKEFKQAFPQVKLIFKPYISNEQAKEQLLQGQLDITFILDVNRMEDALHVES
LIQDEIKMVAANDHPFPADLPVTLKDLQNETLLLTEDGCSYRTLFENNLHDSGIYPNKLEFVSIEAIKQCVMAGLGIGIL
PEMTVKDDIAAGRMKELNWQSDCPVFTQLAWHKDKWMSAPLKAFIDLTRKTFK

Sequences:

>Translated_293_residues
MELKQLITFITAAEHVNFTLTAKMLNYAQSSVTSQIKSLEEEIGTPLFERLGKRLILTEAGKTFKSYAQKIIALTEEAKM
ATNQVRETTGTLKIGATESQCTYRLPPIIKEFKQAFPQVKLIFKPYISNEQAKEQLLQGQLDITFILDVNRMEDALHVES
LIQDEIKMVAANDHPFPADLPVTLKDLQNETLLLTEDGCSYRTLFENNLHDSGIYPNKLEFVSIEAIKQCVMAGLGIGIL
PEMTVKDDIAAGRMKELNWQSDCPVFTQLAWHKDKWMSAPLKAFIDLTRKTFK
>Mature_293_residues
MELKQLITFITAAEHVNFTLTAKMLNYAQSSVTSQIKSLEEEIGTPLFERLGKRLILTEAGKTFKSYAQKIIALTEEAKM
ATNQVRETTGTLKIGATESQCTYRLPPIIKEFKQAFPQVKLIFKPYISNEQAKEQLLQGQLDITFILDVNRMEDALHVES
LIQDEIKMVAANDHPFPADLPVTLKDLQNETLLLTEDGCSYRTLFENNLHDSGIYPNKLEFVSIEAIKQCVMAGLGIGIL
PEMTVKDDIAAGRMKELNWQSDCPVFTQLAWHKDKWMSAPLKAFIDLTRKTFK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI87082132, Length=295, Percent_Identity=28.4745762711864, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=29.6928327645051, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787806, Length=294, Percent_Identity=28.9115646258503, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI157672245, Length=288, Percent_Identity=27.0833333333333, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1790399, Length=250, Percent_Identity=28.8, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790262, Length=247, Percent_Identity=27.5303643724696, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788296, Length=245, Percent_Identity=30.6122448979592, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=26.9360269360269, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=26.8, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787879, Length=257, Percent_Identity=25.6809338521401, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=23.265306122449, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=25.1700680272109, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI145693105, Length=250, Percent_Identity=26, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790208, Length=254, Percent_Identity=24.4094488188976, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788626, Length=250, Percent_Identity=25.2, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=250, Percent_Identity=22.4, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789173, Length=258, Percent_Identity=26.3565891472868, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI2367136, Length=124, Percent_Identity=28.2258064516129, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=149, Percent_Identity=30.8724832214765, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790783, Length=284, Percent_Identity=27.112676056338, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787128, Length=298, Percent_Identity=24.496644295302, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081904, Length=257, Percent_Identity=23.7354085603113, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788706, Length=265, Percent_Identity=25.6603773584906, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): YWQM_BACSU (P96725)

Other databases:

- EMBL:   Z92952
- EMBL:   AL009126
- PIR:   H70067
- RefSeq:   NP_391497.1
- ProteinModelPortal:   P96725
- SMR:   P96725
- EnsemblBacteria:   EBBACT00000003254
- GeneID:   936887
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU36160
- NMPDR:   fig|224308.1.peg.3623
- GenoList:   BSU36160
- GeneTree:   EBGT00070000031761
- HOGENOM:   HBG685425
- OMA:   ASETLMI
- PhylomeDB:   P96725
- ProtClustDB:   CLSK888007
- BioCyc:   BSUB:BSU36160-MONOMER
- GO:   GO:0005737
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 33176; Mature: 33176

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKQLITFITAAEHVNFTLTAKMLNYAQSSVTSQIKSLEEEIGTPLFERLGKRLILTEA
CCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEHHC
GKTFKSYAQKIIALTEEAKMATNQVRETTGTLKIGATESQCTYRLPPIIKEFKQAFPQVK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEECCCHHHHHHHHHCCCEE
LIFKPYISNEQAKEQLLQGQLDITFILDVNRMEDALHVESLIQDEIKMVAANDHPFPADL
EEECCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC
PVTLKDLQNETLLLTEDGCSYRTLFENNLHDSGIYPNKLEFVSIEAIKQCVMAGLGIGIL
CCHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCC
PEMTVKDDIAAGRMKELNWQSDCPVFTQLAWHKDKWMSAPLKAFIDLTRKTFK
CCCCCHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELKQLITFITAAEHVNFTLTAKMLNYAQSSVTSQIKSLEEEIGTPLFERLGKRLILTEA
CCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEHHC
GKTFKSYAQKIIALTEEAKMATNQVRETTGTLKIGATESQCTYRLPPIIKEFKQAFPQVK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEECCCHHHHHHHHHCCCEE
LIFKPYISNEQAKEQLLQGQLDITFILDVNRMEDALHVESLIQDEIKMVAANDHPFPADL
EEECCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC
PVTLKDLQNETLLLTEDGCSYRTLFENNLHDSGIYPNKLEFVSIEAIKQCVMAGLGIGIL
CCHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCC
PEMTVKDDIAAGRMKELNWQSDCPVFTQLAWHKDKWMSAPLKAFIDLTRKTFK
CCCCCHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377