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The map label for this gene is ywrC

Identifier: 16080664

GI number: 16080664

Start: 3720925

End: 3721401

Strand: Direct

Name: ywrC

Synonym: BSU36110

Alternate gene names: 16080664

Gene position: 3720925-3721401 (Clockwise)

Preceding gene: 16080662

Following gene: 16080665

Centisome position: 88.27

GC content: 43.82

Gene sequence:

>477_bases
TTGAGTCATGAATATCAAATCCCCAACCTTGTACTTGATGAGACTGATAAACAAATTCTCACGATTTTGCATGAAGAAGG
CAGAATTTCTTATACGGATCTTGGCAAAAGAGTCGATTTGTCACGGGTCGCCGTTCAGGCCCGTATCAACCAATTAATTG
AAGCCGGTGTTATTGAAAAATTCACCGCTGTCATCAATCCCGCTAAAATCGGCATCCATGTTTCCGTGTTTTTCAATGTC
GAGGTAGAACCGCAATTTTTAGAAGAGGTCGCTCTTAAGCTTGAGGAAGAGCCTGCGGTCACCAGCCTTTATCACATGAC
AGGCCCGAGCAAGCTGCATATGCATGGGATCTTTACCAACGATCAAGAAATGGAAGAATTCTTAACAAAACGGCTGTATC
CATTGCGAGGCGTCGTCAGTGTTGATTGCCAGATGCTGATCAAACGATACAAAAGCCGTATGGGAATGAAGCTGTAA

Upstream 100 bases:

>100_bases
TTTTCGCATTCATTTCGAAAACAAATGAAAAATTATTATTTCTATACGTAACTTTTATGATAAAATGATTGCTAAAAGGC
TACGAAAGCAGGTGGAGCAA

Downstream 100 bases:

>100_bases
AGGAGAGAAACAAATGAAAAACCATCCTTATCGGGATATGACGGCCGCAATGGTTCGCACCGGCATATTAGGGTTCGGCG
GCGGACCTTCCGTGATTCCG

Product: Lrp/AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSHEYQIPNLVLDETDKQILTILHEEGRISYTDLGKRVDLSRVAVQARINQLIEAGVIEKFTAVINPAKIGIHVSVFFNV
EVEPQFLEEVALKLEEEPAVTSLYHMTGPSKLHMHGIFTNDQEMEEFLTKRLYPLRGVVSVDCQMLIKRYKSRMGMKL

Sequences:

>Translated_158_residues
MSHEYQIPNLVLDETDKQILTILHEEGRISYTDLGKRVDLSRVAVQARINQLIEAGVIEKFTAVINPAKIGIHVSVFFNV
EVEPQFLEEVALKLEEEPAVTSLYHMTGPSKLHMHGIFTNDQEMEEFLTKRLYPLRGVVSVDCQMLIKRYKSRMGMKL
>Mature_157_residues
SHEYQIPNLVLDETDKQILTILHEEGRISYTDLGKRVDLSRVAVQARINQLIEAGVIEKFTAVINPAKIGIHVSVFFNVE
VEPQFLEEVALKLEEEPAVTSLYHMTGPSKLHMHGIFTNDQEMEEFLTKRLYPLRGVVSVDCQMLIKRYKSRMGMKL

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YWRC_BACSU (O05217)

Other databases:

- EMBL:   Z93767
- EMBL:   AL009126
- PIR:   E70068
- RefSeq:   NP_391492.1
- HSSP:   P42180
- ProteinModelPortal:   O05217
- SMR:   O05217
- EnsemblBacteria:   EBBACT00000001410
- GeneID:   936886
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU36110
- NMPDR:   fig|224308.1.peg.3618
- GenoList:   BSU36110
- GeneTree:   EBGT00070000032108
- HOGENOM:   HBG740878
- OMA:   FNVEVEP
- ProtClustDB:   CLSK872848
- BioCyc:   BSUB:BSU36110-MONOMER
- GO:   GO:0005622
- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR013199
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00033
- SMART:   SM00344

Pfam domain/function: PF01037 AsnC_trans_reg; PF08280 HTH_Mga; SSF54909 Dimer_A_B_barrel

EC number: NA

Molecular weight: Translated: 18127; Mature: 17996

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00519 HTH_ASNC_1; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHEYQIPNLVLDETDKQILTILHEEGRISYTDLGKRVDLSRVAVQARINQLIEAGVIEK
CCCCCCCCCEEECCCCHHHHHHHHCCCCEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FTAVINPAKIGIHVSVFFNVEVEPQFLEEVALKLEEEPAVTSLYHMTGPSKLHMHGIFTN
HHHHCCCCCEEEEEEEEEEEEECHHHHHHHHHHCCCCCCHHHEEECCCCCEEEEEEEECC
DQEMEEFLTKRLYPLRGVVSVDCQMLIKRYKSRMGMKL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SHEYQIPNLVLDETDKQILTILHEEGRISYTDLGKRVDLSRVAVQARINQLIEAGVIEK
CCCCCCCCEEECCCCHHHHHHHHCCCCEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FTAVINPAKIGIHVSVFFNVEVEPQFLEEVALKLEEEPAVTSLYHMTGPSKLHMHGIFTN
HHHHCCCCCEEEEEEEEEEEEECHHHHHHHHHHCCCCCCHHHEEECCCCCEEEEEEEECC
DQEMEEFLTKRLYPLRGVVSVDCQMLIKRYKSRMGMKL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377