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The map label for this gene is uvrB

Identifier: 16080570

GI number: 16080570

Start: 3612945

End: 3614930

Strand: Reverse

Name: uvrB

Synonym: BSU35170

Alternate gene names: 16080570

Gene position: 3614930-3612945 (Counterclockwise)

Preceding gene: 16080571

Following gene: 16080569

Centisome position: 85.75

GC content: 47.68

Gene sequence:

>1986_bases
GTGAAAGATCGCTTTGAGTTAGTCTCGAAATATCAGCCCCAGGGAGATCAGCCGAAAGCCATTGAAAAGCTTGTGAAAGG
AATTCAGGAGGGCAAGAAGCATCAGACTCTGCTGGGTGCAACAGGAACTGGGAAAACATTTACGGTGTCCAATTTGATTA
AAGAAGTCAATAAGCCGACTCTCGTGATTGCCCATAACAAAACCCTTGCTGGACAGCTTTACAGTGAGTTCAAGGAATTT
TTTCCGAACAATGCTGTCGAGTATTTTGTCAGCTACTATGATTATTATCAGCCGGAGGCGTATGTGCCTCAAACGGATAC
ATTTATAGAGAAAGACGCTAGTATTAATGATGAAATTGATAAACTGAGACACTCCGCCACATCAGCTTTGTTTGAGCGCA
GAGATGTCATTATTATTGCGAGTGTGTCTTGTATATACGGCCTCGGTTCGCCTGAGGAATACCGGGAAATGGTCGTGTCA
CTGCGGACTGAAATGGAAATTGAGCGCAACGAGCTGCTCAGAAAACTTGTAGACATCCAATATGCCCGCAACGATATCGA
CTTTCAGCGCGGTACATTTCGTGTGCGCGGGGATGTAGTGGAAATCTTTCCGGCATCCCGTGATGAGCATTGTGTCAGAG
TTGAATTTTTCGGTGACGAAATCGAACGGATTCGGGAAGTAGATGCGCTGACAGGAGAAATTCTCGGCGACCGAGATCAT
GTTGCGATTTTCCCGGCATCCCACTTCGTAACGCGGGCCGAGAAAATGGAGAAGGCGATTCAAAATATCGAGAAGGAGCT
TGAGGAGCAGCTGAAGGTCATGCATGAAAACGGAAAGCTCCTTGAAGCGCAGCGTTTAGAGCAGCGGACAAGATATGATC
TTGAAATGATGCGTGAAATGGGTTTCTGCTCCGGCATCGAGAACTATTCAAGACATTTGACTCTGCGGCCTCCAGGTTCA
ACGCCGTATACGCTTCTTGATTATTTCCCAGACGATTTTATGATCGTGGTGGATGAGTCGCATGTGACAATTCCTCAGGT
GCGCGGCATGTTTAACGGAGACCAGGCGCGGAAACAGGTGCTCGTGGATCACGGCTTCCGGCTTCCATCAGCGCTTGATA
ACCGTCCGCTTCGTTTTGAGGAATTTGAAAAGCATATGCACAATATCGTGTATGTATCAGCAACACCAGGGCCGTACGAG
ATTGAACATACAGATGAAATGGTCGAACAGATCATTCGTCCGACGGGGCTTCTTGACCCGCTTATTGACGTCCGTCCAAT
CGAAGGTCAGATTGACGACTTGATCGGCGAAATTCAAGCAAGAATCGAGCGGAATGAACGGGTGCTTGTGACAACTTTGA
CGAAGAAGATGTCAGAGGATCTGACCGATTATTTAAAGGAAATCGGCATTAAAGTAAACTATCTGCATTCTGAGATCAAG
ACGCTTGAACGGATTGAAATTATCCGCGACCTGCGCCTTGGCAAGTACGATGTGCTTGTCGGCATCAACCTGCTGAGGGA
AGGTTTGGACATTCCCGAAGTATCCCTTGTTGCGATTTTGGATGCGGATAAGGAAGGTTTCCTTCGTTCGGAGCGGTCGC
TGATCCAGACCATCGGACGGGCAGCGAGAAATGCGGAAGGCCGCGTCATTATGTACGCCGATAAAATAACGAAGTCTATG
GAAATTGCGATTAATGAAACAAAACGCCGCCGCGAGCAGCAGGAGCGGTTTAACGAAGAGCACGGCATTACGCCGAAAAC
GATAAATAAAGAAATTCGCGATGTCATTCGTGCCACAGTAGCAGCTGAGGATAAAGCGGAATACAAAACAAAAGCCGCGC
CGAAGCTGTCGAAAATGACGAAGAAAGAACGCCAGAAAGTCGTTGAACAGATGGAGCATGAAATGAAGGAAGCCGCCAAG
GCGCTTGACTTTGAGAGAGCCGCGGAGCTTCGCGATTTACTTTTAGAGCTAAAAGCGGAAGGATGA

Upstream 100 bases:

>100_bases
AAAACCACCGAACTTTAGTTCGTATTTTTAGTGATTTTGCTTTCCATTGTGTTACTATATCTATAGGAAGATTTCGTTAA
AGAAACGGAGGCTTATTTTT

Downstream 100 bases:

>100_bases
TGAACAAATGGCTATGGATCGGATAGAGGTGAAGGGAGCCAGGGCGCATAACCTGAAAAATATAGATGTAACGATTCCGA
GAGATCAGCTTGTCGTTGTC

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MKDRFELVSKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTGKTFTVSNLIKEVNKPTLVIAHNKTLAGQLYSEFKEF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVS
LRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGDRDH
VAIFPASHFVTRAEKMEKAIQNIEKELEEQLKVMHENGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPPGS
TPYTLLDYFPDDFMIVVDESHVTIPQVRGMFNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYE
IEHTDEMVEQIIRPTGLLDPLIDVRPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIK
TLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITKSM
EIAINETKRRREQQERFNEEHGITPKTINKEIRDVIRATVAAEDKAEYKTKAAPKLSKMTKKERQKVVEQMEHEMKEAAK
ALDFERAAELRDLLLELKAEG

Sequences:

>Translated_661_residues
MKDRFELVSKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTGKTFTVSNLIKEVNKPTLVIAHNKTLAGQLYSEFKEF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVS
LRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGDRDH
VAIFPASHFVTRAEKMEKAIQNIEKELEEQLKVMHENGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPPGS
TPYTLLDYFPDDFMIVVDESHVTIPQVRGMFNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYE
IEHTDEMVEQIIRPTGLLDPLIDVRPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIK
TLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITKSM
EIAINETKRRREQQERFNEEHGITPKTINKEIRDVIRATVAAEDKAEYKTKAAPKLSKMTKKERQKVVEQMEHEMKEAAK
ALDFERAAELRDLLLELKAEG
>Mature_661_residues
MKDRFELVSKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTGKTFTVSNLIKEVNKPTLVIAHNKTLAGQLYSEFKEF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVS
LRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGDRDH
VAIFPASHFVTRAEKMEKAIQNIEKELEEQLKVMHENGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPPGS
TPYTLLDYFPDDFMIVVDESHVTIPQVRGMFNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYE
IEHTDEMVEQIIRPTGLLDPLIDVRPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIK
TLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITKSM
EIAINETKRRREQQERFNEEHGITPKTINKEIRDVIRATVAAEDKAEYKTKAAPKLSKMTKKERQKVVEQMEHEMKEAAK
ALDFERAAELRDLLLELKAEG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=666, Percent_Identity=59.1591591591592, Blast_Score=797, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 76328; Mature: 76328

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRFELVSKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTGKTFTVSNLIKEVNKPT
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHCEEEECCCCCCEEEHHHHHHHCCCCE
LVIAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEID
EEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCHHHH
KLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVSLRTEMEIERNELLRKLVDIQ
HHHHHHHHHHHHCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGDRDH
HHCCCCCCCCCEEEEECCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCC
VAIFPASHFVTRAEKMEKAIQNIEKELEEQLKVMHENGKLLEAQRLEQRTRYDLEMMREM
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GFCSGIENYSRHLTLRPPGSTPYTLLDYFPDDFMIVVDESHVTIPQVRGMFNGDQARKQV
HHHCCCCHHHCEEEECCCCCCCCHHHEECCCCEEEEECCCCCCHHHHHCCCCCHHHHHHH
LVDHGFRLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYEIEHTDEMVEQIIRPTGLLDP
HHHCCCCCCHHCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCC
LIDVRPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIK
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEHHHHHHH
TLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
AARNAEGRVIMYADKITKSMEIAINETKRRREQQERFNEEHGITPKTINKEIRDVIRATV
HHCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAEDKAEYKTKAAPKLSKMTKKERQKVVEQMEHEMKEAAKALDFERAAELRDLLLELKAE
HHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
G
C
>Mature Secondary Structure
MKDRFELVSKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTGKTFTVSNLIKEVNKPT
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHCEEEECCCCCCEEEHHHHHHHCCCCE
LVIAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEID
EEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCHHHH
KLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVSLRTEMEIERNELLRKLVDIQ
HHHHHHHHHHHHCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGDRDH
HHCCCCCCCCCEEEEECCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCC
VAIFPASHFVTRAEKMEKAIQNIEKELEEQLKVMHENGKLLEAQRLEQRTRYDLEMMREM
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GFCSGIENYSRHLTLRPPGSTPYTLLDYFPDDFMIVVDESHVTIPQVRGMFNGDQARKQV
HHHCCCCHHHCEEEECCCCCCCCHHHEECCCCEEEEECCCCCCHHHHHCCCCCHHHHHHH
LVDHGFRLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYEIEHTDEMVEQIIRPTGLLDP
HHHCCCCCCHHCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCC
LIDVRPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIK
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEHHHHHHH
TLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
AARNAEGRVIMYADKITKSMEIAINETKRRREQQERFNEEHGITPKTINKEIRDVIRATV
HHCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAEDKAEYKTKAAPKLSKMTKKERQKVVEQMEHEMKEAAKALDFERAAELRDLLLELKAE
HHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA