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The map label for this gene is lysP

Identifier: 16080387

GI number: 16080387

Start: 3419656

End: 3421065

Strand: Reverse

Name: lysP

Synonym: BSU33330

Alternate gene names: 16080387

Gene position: 3421065-3419656 (Counterclockwise)

Preceding gene: 50812294

Following gene: 16080385

Centisome position: 81.15

GC content: 46.1

Gene sequence:

>1410_bases
ATGGAACAGACAAAAAAATGGGGTTTTTGGTTATTAACGGCGTTTGTCGTTGGAAATATGGTTGGATCAGGAATTTTCTC
CTTGCCGAGCTCGCTTGCTTCAATTGCGAGTCCGTTTGGAGCTACGTCCGCCTGGCTTTTGACAGGTGCCGGCGTGCTGA
TGATTGCACTTGTGTTCGGACACTTGTCCATTCGCAAGCCTGAACTGACAGCGGGACCGCAAAGTTATGCAAGAGCGCTG
TTTTCTGACCCGAAAAAAGGCAACGCTGCCGGTTTCACAATGGTGTGGGGCTACTGGGTGGCGAGCTGGATCAGTAACGT
GGCGATCATCACAAGTCTCGCCGGTTACTTGACTTCGTTCTTCCCGATCTTGGTTGATAAACGTGAGATGTTTTCGATCG
GCGGGCAAGAGGTGACACTCGGCCAATTACTGACGTTTGCCGTATGTACGATCTTGTTATGGGGAACGCACGCGATTCTT
GTTGCCAGCATTAACGGCGCAAGTAAATTAAACTTTGTCACAACGCTTTCTAAAGTATTAGGTTTTGTCTTCTTTATCGT
TGCCGGTTTGTTTGTGTTTCAAACGTCATTATTCGGTCATTTTTATTTCCCGGTTCAAGGAGAAAACGGCACAAGCATTG
GAATTGGTGGCCAGGTTCATAACGCTGCGATTTCTACACTGTGGGCGTTTGTCGGAATTGAATCCGCGGTGATCCTGTCC
GGCCGTGCGCGCTCTCAGCGTGATGTGAAACGTGCGACAATTACCGGCTTGCTGATTGCCTTGAGCATATATATTATTGT
GACTTTAATTACGATGGGTGTTCTGCCGCATGATAAGCTTGTCGGCTCTGAAAAACCATTTGTTGATGTACTCTATGCGA
TTGTTGGAAACGCGGGAAGCGTGATTATGGCGCTTTTGGCTATCCTTTGTTTATTCGGAACGATGCTCGGCTGGATTTTG
CTTGGCTCTGAGGTGCCATACCAAGCCGCTAAAGCAGGAGATTTCCCGGCATTTTTTGCAAAAACGAATAAAAAGGGAAG
TCCGGTCATTGCACTCATTATTACAAACGTCATGTCACAGGTCTTCATTTTCTCGGTTATTTCCCGGACAATAAGTGACG
CATTTACATTTTTAACGACAGCGGCTACACTCGCATATTTAATTCCGTATCTGGTATCTGCAATCTACAGCTTGAAGGTA
GTCATCAAAGGTGAAACGTATGACCAGCTGAAAGGCTCCCGTGTAAGAGACGGATTGATCGCGATACTGGCGTGTGCATA
CTCCGTGTTTGTTATCGTAACAGGCACAGCAGATTTAACGACATTTATACTCGGCATCGGTTTATTCTTTGTCGGCTTAA
TCGTTTATCCATTTGTGAGTAACAAGTTCCAGAAAGAAAAACAAGCATAA

Upstream 100 bases:

>100_bases
AGGGTGTGTGTTTCTTTAAGCATGGACTTTTGTTCAGGCTTTTTTTGCGTTTATATGATCTCGGGGTCTGGTCCGTACAA
AGAATCATGGAGGTACTGGA

Downstream 100 bases:

>100_bases
TGAAAAGACACCTGATTTGCTCAGGTGTCTTTTTTATAAAATCACAATTTCTCCTGTTAGGAATCCGTTCGTTAAATATG
CAAAAAACGTTTTTCAGTCT

Product: lysine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MEQTKKWGFWLLTAFVVGNMVGSGIFSLPSSLASIASPFGATSAWLLTGAGVLMIALVFGHLSIRKPELTAGPQSYARAL
FSDPKKGNAAGFTMVWGYWVASWISNVAIITSLAGYLTSFFPILVDKREMFSIGGQEVTLGQLLTFAVCTILLWGTHAIL
VASINGASKLNFVTTLSKVLGFVFFIVAGLFVFQTSLFGHFYFPVQGENGTSIGIGGQVHNAAISTLWAFVGIESAVILS
GRARSQRDVKRATITGLLIALSIYIIVTLITMGVLPHDKLVGSEKPFVDVLYAIVGNAGSVIMALLAILCLFGTMLGWIL
LGSEVPYQAAKAGDFPAFFAKTNKKGSPVIALIITNVMSQVFIFSVISRTISDAFTFLTTAATLAYLIPYLVSAIYSLKV
VIKGETYDQLKGSRVRDGLIAILACAYSVFVIVTGTADLTTFILGIGLFFVGLIVYPFVSNKFQKEKQA

Sequences:

>Translated_469_residues
MEQTKKWGFWLLTAFVVGNMVGSGIFSLPSSLASIASPFGATSAWLLTGAGVLMIALVFGHLSIRKPELTAGPQSYARAL
FSDPKKGNAAGFTMVWGYWVASWISNVAIITSLAGYLTSFFPILVDKREMFSIGGQEVTLGQLLTFAVCTILLWGTHAIL
VASINGASKLNFVTTLSKVLGFVFFIVAGLFVFQTSLFGHFYFPVQGENGTSIGIGGQVHNAAISTLWAFVGIESAVILS
GRARSQRDVKRATITGLLIALSIYIIVTLITMGVLPHDKLVGSEKPFVDVLYAIVGNAGSVIMALLAILCLFGTMLGWIL
LGSEVPYQAAKAGDFPAFFAKTNKKGSPVIALIITNVMSQVFIFSVISRTISDAFTFLTTAATLAYLIPYLVSAIYSLKV
VIKGETYDQLKGSRVRDGLIAILACAYSVFVIVTGTADLTTFILGIGLFFVGLIVYPFVSNKFQKEKQA
>Mature_469_residues
MEQTKKWGFWLLTAFVVGNMVGSGIFSLPSSLASIASPFGATSAWLLTGAGVLMIALVFGHLSIRKPELTAGPQSYARAL
FSDPKKGNAAGFTMVWGYWVASWISNVAIITSLAGYLTSFFPILVDKREMFSIGGQEVTLGQLLTFAVCTILLWGTHAIL
VASINGASKLNFVTTLSKVLGFVFFIVAGLFVFQTSLFGHFYFPVQGENGTSIGIGGQVHNAAISTLWAFVGIESAVILS
GRARSQRDVKRATITGLLIALSIYIIVTLITMGVLPHDKLVGSEKPFVDVLYAIVGNAGSVIMALLAILCLFGTMLGWIL
LGSEVPYQAAKAGDFPAFFAKTNKKGSPVIALIITNVMSQVFIFSVISRTISDAFTFLTTAATLAYLIPYLVSAIYSLKV
VIKGETYDQLKGSRVRDGLIAILACAYSVFVIVTGTADLTTFILGIGLFFVGLIVYPFVSNKFQKEKQA

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily

Homologues:

Organism=Escherichia coli, GI1787890, Length=467, Percent_Identity=31.2633832976445, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI2367353, Length=396, Percent_Identity=31.5656565656566, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1790575, Length=483, Percent_Identity=27.536231884058, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786908, Length=474, Percent_Identity=26.7932489451477, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082250, Length=372, Percent_Identity=26.3440860215054, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71982608, Length=370, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982612, Length=370, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71995382, Length=485, Percent_Identity=25.360824742268, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71995388, Length=485, Percent_Identity=25.360824742268, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARCD_BACSU (O32204)

Other databases:

- EMBL:   AJ223978
- EMBL:   AL009126
- PIR:   D70048
- RefSeq:   NP_391214.1
- ProteinModelPortal:   O32204
- SMR:   O32204
- EnsemblBacteria:   EBBACT00000000032
- GeneID:   936000
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU33330
- NMPDR:   fig|224308.1.peg.3340
- GenoList:   BSU33330
- GeneTree:   EBGT00050000000869
- HOGENOM:   HBG586921
- OMA:   NMVGSGI
- PhylomeDB:   O32204
- ProtClustDB:   CLSK887868
- BioCyc:   BSUB:BSU33330-MONOMER
- InterPro:   IPR004841
- InterPro:   IPR002293
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 50259; Mature: 50259

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1177b4f0)-; HASH(0x121ff8ec)-; HASH(0x11cc021c)-; HASH(0x112c2d04)-; HASH(0x1221d668)-; HASH(0xd6fbde4)-; HASH(0x12453b30)-; HASH(0x118a7318)-; HASH(0x112bdb5c)-; HASH(0x118175e8)-; HASH(0x11e57c24)-; HASH(0x1253f7e0)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTKKWGFWLLTAFVVGNMVGSGIFSLPSSLASIASPFGATSAWLLTGAGVLMIALVFG
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
HLSIRKPELTAGPQSYARALFSDPKKGNAAGFTMVWGYWVASWISNVAIITSLAGYLTSF
HHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPILVDKREMFSIGGQEVTLGQLLTFAVCTILLWGTHAILVASINGASKLNFVTTLSKVL
HHHHHCCHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHH
GFVFFIVAGLFVFQTSLFGHFYFPVQGENGTSIGIGGQVHNAAISTLWAFVGIESAVILS
HHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHCCHHEEEC
GRARSQRDVKRATITGLLIALSIYIIVTLITMGVLPHDKLVGSEKPFVDVLYAIVGNAGS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHCCCHH
VIMALLAILCLFGTMLGWILLGSEVPYQAAKAGDFPAFFAKTNKKGSPVIALIITNVMSQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHH
VFIFSVISRTISDAFTFLTTAATLAYLIPYLVSAIYSLKVVIKGETYDQLKGSRVRDGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHCCCHHHHHHH
AILACAYSVFVIVTGTADLTTFILGIGLFFVGLIVYPFVSNKFQKEKQA
HHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MEQTKKWGFWLLTAFVVGNMVGSGIFSLPSSLASIASPFGATSAWLLTGAGVLMIALVFG
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
HLSIRKPELTAGPQSYARALFSDPKKGNAAGFTMVWGYWVASWISNVAIITSLAGYLTSF
HHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPILVDKREMFSIGGQEVTLGQLLTFAVCTILLWGTHAILVASINGASKLNFVTTLSKVL
HHHHHCCHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHH
GFVFFIVAGLFVFQTSLFGHFYFPVQGENGTSIGIGGQVHNAAISTLWAFVGIESAVILS
HHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHCCHHEEEC
GRARSQRDVKRATITGLLIALSIYIIVTLITMGVLPHDKLVGSEKPFVDVLYAIVGNAGS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHCCCHH
VIMALLAILCLFGTMLGWILLGSEVPYQAAKAGDFPAFFAKTNKKGSPVIALIITNVMSQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHH
VFIFSVISRTISDAFTFLTTAATLAYLIPYLVSAIYSLKVVIKGETYDQLKGSRVRDGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHCCCHHHHHHH
AILACAYSVFVIVTGTADLTTFILGIGLFFVGLIVYPFVSNKFQKEKQA
HHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377