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The map label for this gene is tlpB

Identifier: 16080175

GI number: 16080175

Start: 3204067

End: 3206055

Strand: Reverse

Name: tlpB

Synonym: BSU31230

Alternate gene names: 16080175

Gene position: 3206055-3204067 (Counterclockwise)

Preceding gene: 255767704

Following gene: 16080174

Centisome position: 76.05

GC content: 43.19

Gene sequence:

>1989_bases
ATGGGAAAATTCATACAATGGATCAAACAGCCATCGATCAGCAAACCGCTAATCGCTGCGTTTCTGGCAGTGCTTATTTT
GCCGGTTGGGGTTTTAGCATATTTCAGTTATCAATCAGCTTGGAACGCGTTAGACAGAGAGCTCATAAGCAGTGCGAAGG
GAAATGTTGAAGAACTAAACAGTACGCTGCAAAATAAATTAGAAGATAAAGTAAAAGCAATAGATTATTATAGTGAGACA
GTCGATAAAGACATATTGTTAGGCAAAAACAAAACATTACTGAAAGAGAAATTTAAGCAGTACACGACACTTAACGACGA
TGTAGGCGCAATCTATGCTGCCTCAGAAGATAAGAAGCTTTATAAATATCCGGATAGCGGTGTTCCGAAAGGTTTCGATC
CGACAGGACGTGACTGGTACAAACAGGCGGTTGCGGAAAAAGGACAAGCTGTTTTCTCAGAACCGTATACCGATGAAGCG
ACAGGAGATATCGTTGTCACAATTTCAAAACAATTAAAAGACGGTTCAGGGGTTATAGCGCTAGATTTAAACCTGGATGA
AGTGCTTACTGCATCAAAAAGAATCAAAATCGGAAAAGAAGGCTTTGCATTTATTACGACAGGCAACAAAAAATATATCG
CCCATCCGACCATTAAGCCGGGGACAACCGGTTCCGGCGATTGGACAAACCAAGTATATTCCAAAAAAGAAGGCTCATTT
GAATATACATTCGAAGGCAAAGAAAAGAAAATGGCCTTTACGACAAATAAACTGACTGGCTGGAAAATCGCGGGCACATA
TTTTGTCAGTGAATTGCAAGATGCTTCAAGCCCGGTGCTGAACACTGCGGTTATCATTCTATGCGTGTCAATAGTAATCG
GCGGCATACTCATACTCTATATTATCCGTGCCATCACCAAGCCGTTAAGAAAACTTGTCTCAACGTCTGCAAAAATCAGC
AGCGGAGATCTCACAGAAGTCATTGACATTCACTCGAAAAACGAGTTTGGCCAGCTTGGCGAAAGCTTTAATGAAATGTC
TGCATCATTGCGTTCTGTAATAGGCGTTATTCAAACGTCTGTAGAAAACGTCGCTTCATCTTCTGAGGAGCTGACAGCAA
GCGCAGCCCAAACAAGCAAGGCAACTGAACATATTACACTTGCCATCGAACAGTTCTCAGATGGCAACGAGGCACAAAGC
GAGAAACTGGAAACAAGCTCAAATCATCTTTCTCAAATGAACGAGGGGATTTCAAAAGTGGCTCAAGCCTCTTCAACCAT
TACGAAATCATCGATTCAGTCCTCTGAGGCAGCGGGCAGCGGAGAAAAGCTGGTGGAGCATACAGTCGGCCAGATGAAAA
CAATTGACCAATCCGTTCAAAAAGCGGAAGCGGTTGTGAAGGGCCTTGAAACAAAATCGCAAGACATCACAAGCATCTTG
AATGTGATTAACGGCATTGCTGATCAAACCAACCTGCTTGCATTAAATGCTGCGATTGAGGCGGCAAGAGCGGGAGAATA
CGGAAGAGGTTTCTCAGTAGTTGCGGAAGAGGTTAGAAAACTTGCTGTACAATCAGCAGACTCCGCCAAGGAAATTGAAG
GATTAATTCAAGAGATTGTCAGGGAAATCAGCACCTCACTTTCAATGTTCCAATCCGTGAATCATGAAGTGAAAGAAGGC
TTGCAGATTACGGATCAAACAGCGGAAAGCTTTAAACAAATCTATGAGATGACAACCCAAATTTCCGGCGAATTGCAAAA
CTTGAACGCGACGGTTGAACAACTGTCAGCCGGATCACAGGAAGTGTCAAGTGCTGTTGAAGATATTTCTGCAGTGGCGA
AAGAAAGCTCAGCAGGCATTCAGGATATCGCAGCTTCGGCGGAAGAACAGCTTGCGTCCATGGAAGAAATCAGCTCTTCA
GCGGAAACGTTGGCAAACATGGCGGAAGAACTTCAGGACATTACGAAGAAATTTAAAATAGAATCATAA

Upstream 100 bases:

>100_bases
CCAAGCTTGTTGCGCTTGGGTGTTTTTTTTAGTTTTTTTATTAAACCTTTTATCCTAGTTTGACGATATTAGATTTATCT
TAAAGGAGGAGTCAACGAGA

Downstream 100 bases:

>100_bases
TGAAACGAGAAAGCGGCATATCTGCTGCTTTCTTTTTTTGTTAAAAAGCAAAAATAAACAAAAACGATTCAAAAACAAAC
AGAAATCATATATAATGAAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MGKFIQWIKQPSISKPLIAAFLAVLILPVGVLAYFSYQSAWNALDRELISSAKGNVEELNSTLQNKLEDKVKAIDYYSET
VDKDILLGKNKTLLKEKFKQYTTLNDDVGAIYAASEDKKLYKYPDSGVPKGFDPTGRDWYKQAVAEKGQAVFSEPYTDEA
TGDIVVTISKQLKDGSGVIALDLNLDEVLTASKRIKIGKEGFAFITTGNKKYIAHPTIKPGTTGSGDWTNQVYSKKEGSF
EYTFEGKEKKMAFTTNKLTGWKIAGTYFVSELQDASSPVLNTAVIILCVSIVIGGILILYIIRAITKPLRKLVSTSAKIS
SGDLTEVIDIHSKNEFGQLGESFNEMSASLRSVIGVIQTSVENVASSSEELTASAAQTSKATEHITLAIEQFSDGNEAQS
EKLETSSNHLSQMNEGISKVAQASSTITKSSIQSSEAAGSGEKLVEHTVGQMKTIDQSVQKAEAVVKGLETKSQDITSIL
NVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIEGLIQEIVREISTSLSMFQSVNHEVKEG
LQITDQTAESFKQIYEMTTQISGELQNLNATVEQLSAGSQEVSSAVEDISAVAKESSAGIQDIAASAEEQLASMEEISSS
AETLANMAEELQDITKKFKIES

Sequences:

>Translated_662_residues
MGKFIQWIKQPSISKPLIAAFLAVLILPVGVLAYFSYQSAWNALDRELISSAKGNVEELNSTLQNKLEDKVKAIDYYSET
VDKDILLGKNKTLLKEKFKQYTTLNDDVGAIYAASEDKKLYKYPDSGVPKGFDPTGRDWYKQAVAEKGQAVFSEPYTDEA
TGDIVVTISKQLKDGSGVIALDLNLDEVLTASKRIKIGKEGFAFITTGNKKYIAHPTIKPGTTGSGDWTNQVYSKKEGSF
EYTFEGKEKKMAFTTNKLTGWKIAGTYFVSELQDASSPVLNTAVIILCVSIVIGGILILYIIRAITKPLRKLVSTSAKIS
SGDLTEVIDIHSKNEFGQLGESFNEMSASLRSVIGVIQTSVENVASSSEELTASAAQTSKATEHITLAIEQFSDGNEAQS
EKLETSSNHLSQMNEGISKVAQASSTITKSSIQSSEAAGSGEKLVEHTVGQMKTIDQSVQKAEAVVKGLETKSQDITSIL
NVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIEGLIQEIVREISTSLSMFQSVNHEVKEG
LQITDQTAESFKQIYEMTTQISGELQNLNATVEQLSAGSQEVSSAVEDISAVAKESSAGIQDIAASAEEQLASMEEISSS
AETLANMAEELQDITKKFKIES
>Mature_661_residues
GKFIQWIKQPSISKPLIAAFLAVLILPVGVLAYFSYQSAWNALDRELISSAKGNVEELNSTLQNKLEDKVKAIDYYSETV
DKDILLGKNKTLLKEKFKQYTTLNDDVGAIYAASEDKKLYKYPDSGVPKGFDPTGRDWYKQAVAEKGQAVFSEPYTDEAT
GDIVVTISKQLKDGSGVIALDLNLDEVLTASKRIKIGKEGFAFITTGNKKYIAHPTIKPGTTGSGDWTNQVYSKKEGSFE
YTFEGKEKKMAFTTNKLTGWKIAGTYFVSELQDASSPVLNTAVIILCVSIVIGGILILYIIRAITKPLRKLVSTSAKISS
GDLTEVIDIHSKNEFGQLGESFNEMSASLRSVIGVIQTSVENVASSSEELTASAAQTSKATEHITLAIEQFSDGNEAQSE
KLETSSNHLSQMNEGISKVAQASSTITKSSIQSSEAAGSGEKLVEHTVGQMKTIDQSVQKAEAVVKGLETKSQDITSILN
VINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIEGLIQEIVREISTSLSMFQSVNHEVKEGL
QITDQTAESFKQIYEMTTQISGELQNLNATVEQLSAGSQEVSSAVEDISAVAKESSAGIQDIAASAEEQLASMEEISSSA
ETLANMAEELQDITKKFKIES

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain

Homologues:

Organism=Escherichia coli, GI2367378, Length=335, Percent_Identity=29.2537313432836, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1787690, Length=356, Percent_Identity=32.3033707865169, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1788194, Length=407, Percent_Identity=28.7469287469287, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1788195, Length=318, Percent_Identity=28.6163522012579, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789453, Length=360, Percent_Identity=27.5, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TLPB_BACSU (P39217)

Other databases:

- EMBL:   L29189
- EMBL:   AL009126
- PIR:   D54078
- RefSeq:   NP_391001.1
- ProteinModelPortal:   P39217
- EnsemblBacteria:   EBBACT00000000505
- GeneID:   937152
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31230
- NMPDR:   fig|224308.1.peg.3126
- GenoList:   BSU31230
- GeneTree:   EBGT00070000031772
- HOGENOM:   HBG338974
- OMA:   SSHRIAD
- ProtClustDB:   CLSK2301479
- BioCyc:   BSUB:BSU31230-MONOMER
- GO:   GO:0006935
- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094
- SMART:   SM00304
- SMART:   SM00283
- SMART:   SM00319

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH

EC number: NA

Molecular weight: Translated: 71536; Mature: 71405

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00538 CHEMOTAXIS_TRANSDUC_1; PS50111 CHEMOTAXIS_TRANSDUC_2; PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11e1ae78)-; HASH(0x11fc3ba0)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFIQWIKQPSISKPLIAAFLAVLILPVGVLAYFSYQSAWNALDRELISSAKGNVEELN
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
STLQNKLEDKVKAIDYYSETVDKDILLGKNKTLLKEKFKQYTTLNDDVGAIYAASEDKKL
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCE
YKYPDSGVPKGFDPTGRDWYKQAVAEKGQAVFSEPYTDEATGDIVVTISKQLKDGSGVIA
EECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEEEEHHCCCCCCEEE
LDLNLDEVLTASKRIKIGKEGFAFITTGNKKYIAHPTIKPGTTGSGDWTNQVYSKKEGSF
EECCHHHHHHHHHHHEECCCCEEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCE
EYTFEGKEKKMAFTTNKLTGWKIAGTYFVSELQDASSPVLNTAVIILCVSIVIGGILILY
EEEECCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IIRAITKPLRKLVSTSAKISSGDLTEVIDIHSKNEFGQLGESFNEMSASLRSVIGVIQTS
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VENVASSSEELTASAAQTSKATEHITLAIEQFSDGNEAQSEKLETSSNHLSQMNEGISKV
HHHHHCCHHHHHHHHHHHHHCHHHHEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQASSTITKSSIQSSEAAGSGEKLVEHTVGQMKTIDQSVQKAEAVVKGLETKSQDITSIL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIEGLIQEIV
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
REISTSLSMFQSVNHEVKEGLQITDQTAESFKQIYEMTTQISGELQNLNATVEQLSAGSQ
HHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EVSSAVEDISAVAKESSAGIQDIAASAEEQLASMEEISSSAETLANMAEELQDITKKFKI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ES
CH
>Mature Secondary Structure 
GKFIQWIKQPSISKPLIAAFLAVLILPVGVLAYFSYQSAWNALDRELISSAKGNVEELN
CHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
STLQNKLEDKVKAIDYYSETVDKDILLGKNKTLLKEKFKQYTTLNDDVGAIYAASEDKKL
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCE
YKYPDSGVPKGFDPTGRDWYKQAVAEKGQAVFSEPYTDEATGDIVVTISKQLKDGSGVIA
EECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEEEEHHCCCCCCEEE
LDLNLDEVLTASKRIKIGKEGFAFITTGNKKYIAHPTIKPGTTGSGDWTNQVYSKKEGSF
EECCHHHHHHHHHHHEECCCCEEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCE
EYTFEGKEKKMAFTTNKLTGWKIAGTYFVSELQDASSPVLNTAVIILCVSIVIGGILILY
EEEECCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IIRAITKPLRKLVSTSAKISSGDLTEVIDIHSKNEFGQLGESFNEMSASLRSVIGVIQTS
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VENVASSSEELTASAAQTSKATEHITLAIEQFSDGNEAQSEKLETSSNHLSQMNEGISKV
HHHHHCCHHHHHHHHHHHHHCHHHHEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQASSTITKSSIQSSEAAGSGEKLVEHTVGQMKTIDQSVQKAEAVVKGLETKSQDITSIL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIEGLIQEIV
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
REISTSLSMFQSVNHEVKEGLQITDQTAESFKQIYEMTTQISGELQNLNATVEQLSAGSQ
HHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EVSSAVEDISAVAKESSAGIQDIAASAEEQLASMEEISSSAETLANMAEELQDITKKFKI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ES
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377