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The map label for this gene is mntC

Identifier: 16080127

GI number: 16080127

Start: 3142954

End: 3144261

Strand: Reverse

Name: mntC

Synonym: BSU30750

Alternate gene names: 16080127

Gene position: 3144261-3142954 (Counterclockwise)

Preceding gene: 16080128

Following gene: 16080126

Centisome position: 74.59

GC content: 47.71

Gene sequence:

>1308_bases
ATGTTTGAAAGTTTGTGGCTGCAGCTTCAGCATCCGAATACACAGTGGGTGCTGGCCGGTACGCTTTTGCTCGGGACGGC
AAGCGGTGTTTTGGGCAGCTTTGTGCTGCTGAGAAAGCAAAGTTTAATCGGCGATGCGATGGCCCATTCAGCTCTGCCGG
GAGTGTGTCTCGCTTTTCTGTTCACCGGGCAAAAATCACTGCCTTTCTTTTTGCTGGGGGCAGCGCTCGCCGGACTGCTC
GGAACGTTTTGTATTCAGCTGATTCCTCGGCTTTCAAAAACAAAGGAGGACTCGGCGATCGGGATTGTTCTTTCTGTGTT
TTTTGGCGTCGGGATCATTCTGCTGACATATATTCAGCAACAGGGGGCGGGAAGCCAAAGCGGGCTTGATTCTTTTTTAT
TCGGCCAGGCTGCTTCATTGGTCAGGCAGGATATCATCCTTATTGCAGGGATATCCGCTGTTCTACTGCTCCTATGTATT
GTTTTCTTTAAGGAATTTACATTGATTACTTTTGATCTCGCGTTTGCAAAGGGATTAGGAATCCCGGTGCGTTTTTTAAA
CGGGCTTTTGGCTTGTCTGATTGTCTGTGCTGTCGTCATTGGGCTTCAGACTGTTGGTGTGATATTAATGGCGGCTATGC
TGATTACACCTGCCATAACCGCGAGATATTGGACCGAACGATTAACCGGGATGATCATCATTGCCGGGATTACAGGCGGG
GTCAGCGGAGTGGCCGGAACCCTGCTTAGCACCACGATGAAGGGAATGGCGACAGGGCCATTAATGATCTTATCTGCAAC
GCTGCTCTTTCTTTTTTCAATGATTTGCGCGCCTAAGCGGGGATTGGCTGCTAAAGCCATAAGGCTGATGAGGCTGCGGC
GCAGAACAAGCAGGGAGCAAGTGCTTTTGGCGATTTATGAACAGTATGAAAAGAATAATCTTTGTGTAACTGTTGAAAGT
GTAAGAAAGAAAAGACGCCTATCCCCTTCATTATGCCTTAAGGCATTAAATGACTTGGAACAAGAGAGGTGCATTGAGCG
TATCGAAAATGGGATTTGGCAAATCACAAGCAAAGGGATAGAAAAAGGCTATCACACAGCTTTGAAGCAGCGGATGTATG
AAGTGTATCTCATGCATGAAATGGAACTTGCCAATATAGAATCCGATCAGGACTACTTTGACCCGGACCGTTTACCGAGA
GAAACGAGAGAGCGGCTTTATTCACTCTTAAAGCTGTATGGACGGATGCCTGAGCGTCGAAAAGCGTCTCATGATGCCGA
GAAGGGACAGATCGCAAATGAGTTTTGA

Upstream 100 bases:

>100_bases
AAAACGTTTTTACGATCGAAAACCTGCAAAAAACATATGGAGGAAGGCTTACGTTTTTAAAAGATAAAGTGCTGGCAGAA
GGACATAAGGAGTGAGCGCA

Downstream 100 bases:

>100_bases
AGCATGGATTATAGCTACCGGTGTATTAGTCGGTGTAAGCTGCGGATTGATCGGCACATTTCTTGTGCTGAGAAGCATGG
CGATGCTGGCCGACGCAATC

Product: manganese ABC transporter permease

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MFESLWLQLQHPNTQWVLAGTLLLGTASGVLGSFVLLRKQSLIGDAMAHSALPGVCLAFLFTGQKSLPFFLLGAALAGLL
GTFCIQLIPRLSKTKEDSAIGIVLSVFFGVGIILLTYIQQQGAGSQSGLDSFLFGQAASLVRQDIILIAGISAVLLLLCI
VFFKEFTLITFDLAFAKGLGIPVRFLNGLLACLIVCAVVIGLQTVGVILMAAMLITPAITARYWTERLTGMIIIAGITGG
VSGVAGTLLSTTMKGMATGPLMILSATLLFLFSMICAPKRGLAAKAIRLMRLRRRTSREQVLLAIYEQYEKNNLCVTVES
VRKKRRLSPSLCLKALNDLEQERCIERIENGIWQITSKGIEKGYHTALKQRMYEVYLMHEMELANIESDQDYFDPDRLPR
ETRERLYSLLKLYGRMPERRKASHDAEKGQIANEF

Sequences:

>Translated_435_residues
MFESLWLQLQHPNTQWVLAGTLLLGTASGVLGSFVLLRKQSLIGDAMAHSALPGVCLAFLFTGQKSLPFFLLGAALAGLL
GTFCIQLIPRLSKTKEDSAIGIVLSVFFGVGIILLTYIQQQGAGSQSGLDSFLFGQAASLVRQDIILIAGISAVLLLLCI
VFFKEFTLITFDLAFAKGLGIPVRFLNGLLACLIVCAVVIGLQTVGVILMAAMLITPAITARYWTERLTGMIIIAGITGG
VSGVAGTLLSTTMKGMATGPLMILSATLLFLFSMICAPKRGLAAKAIRLMRLRRRTSREQVLLAIYEQYEKNNLCVTVES
VRKKRRLSPSLCLKALNDLEQERCIERIENGIWQITSKGIEKGYHTALKQRMYEVYLMHEMELANIESDQDYFDPDRLPR
ETRERLYSLLKLYGRMPERRKASHDAEKGQIANEF
>Mature_435_residues
MFESLWLQLQHPNTQWVLAGTLLLGTASGVLGSFVLLRKQSLIGDAMAHSALPGVCLAFLFTGQKSLPFFLLGAALAGLL
GTFCIQLIPRLSKTKEDSAIGIVLSVFFGVGIILLTYIQQQGAGSQSGLDSFLFGQAASLVRQDIILIAGISAVLLLLCI
VFFKEFTLITFDLAFAKGLGIPVRFLNGLLACLIVCAVVIGLQTVGVILMAAMLITPAITARYWTERLTGMIIIAGITGG
VSGVAGTLLSTTMKGMATGPLMILSATLLFLFSMICAPKRGLAAKAIRLMRLRRRTSREQVLLAIYEQYEKNNLCVTVES
VRKKRRLSPSLCLKALNDLEQERCIERIENGIWQITSKGIEKGYHTALKQRMYEVYLMHEMELANIESDQDYFDPDRLPR
ETRERLYSLLKLYGRMPERRKASHDAEKGQIANEF

Specific function: This protein is probably a component of a manganese permease, a binding protein-dependent, ATP-driven transport system

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family

Homologues:

Organism=Escherichia coli, GI1788166, Length=270, Percent_Identity=30, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNTC_BACSU (O35024)

Other databases:

- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   D69992
- RefSeq:   NP_390953.1
- ProteinModelPortal:   O35024
- SMR:   O35024
- EnsemblBacteria:   EBBACT00000000138
- GeneID:   937203
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU30750
- NMPDR:   fig|224308.1.peg.3078
- GenoList:   BSU30750
- GeneTree:   EBGT00050000000881
- HOGENOM:   HBG733179
- OMA:   GICIAFM
- PhylomeDB:   O35024
- ProtClustDB:   CLSK2502632
- BioCyc:   BSUB:BSU30750-MONOMER
- InterPro:   IPR001626
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF00950 ABC-3

EC number: NA

Molecular weight: Translated: 47946; Mature: 47946

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11b107d4)-; HASH(0x114dfef8)-; HASH(0x11d7f720)-; HASH(0xb48a0c4)-; HASH(0x11d94a90)-; HASH(0x11f1433c)-; HASH(0xf2e3640)-; HASH(0x11a705ac)-; HASH(0x11f1445c)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESLWLQLQHPNTQWVLAGTLLLGTASGVLGSFVLLRKQSLIGDAMAHSALPGVCLAFL
CCCHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
FTGQKSLPFFLLGAALAGLLGTFCIQLIPRLSKTKEDSAIGIVLSVFFGVGIILLTYIQQ
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QGAGSQSGLDSFLFGQAASLVRQDIILIAGISAVLLLLCIVFFKEFTLITFDLAFAKGLG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPVRFLNGLLACLIVCAVVIGLQTVGVILMAAMLITPAITARYWTERLTGMIIIAGITGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
VSGVAGTLLSTTMKGMATGPLMILSATLLFLFSMICAPKRGLAAKAIRLMRLRRRTSREQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHH
VLLAIYEQYEKNNLCVTVESVRKKRRLSPSLCLKALNDLEQERCIERIENGIWQITSKGI
HHHHHHHHHCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGYHTALKQRMYEVYLMHEMELANIESDQDYFDPDRLPRETRERLYSLLKLYGRMPERR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHH
KASHDAEKGQIANEF
HHCCCCCCCCCCCCH
>Mature Secondary Structure
MFESLWLQLQHPNTQWVLAGTLLLGTASGVLGSFVLLRKQSLIGDAMAHSALPGVCLAFL
CCCHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
FTGQKSLPFFLLGAALAGLLGTFCIQLIPRLSKTKEDSAIGIVLSVFFGVGIILLTYIQQ
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QGAGSQSGLDSFLFGQAASLVRQDIILIAGISAVLLLLCIVFFKEFTLITFDLAFAKGLG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPVRFLNGLLACLIVCAVVIGLQTVGVILMAAMLITPAITARYWTERLTGMIIIAGITGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
VSGVAGTLLSTTMKGMATGPLMILSATLLFLFSMICAPKRGLAAKAIRLMRLRRRTSREQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHH
VLLAIYEQYEKNNLCVTVESVRKKRRLSPSLCLKALNDLEQERCIERIENGIWQITSKGI
HHHHHHHHHCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGYHTALKQRMYEVYLMHEMELANIESDQDYFDPDRLPRETRERLYSLLKLYGRMPERR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHH
KASHDAEKGQIANEF
HHCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10760146