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The map label for this gene is bceS

Identifier: 16080091

GI number: 16080091

Start: 3112190

End: 3113194

Strand: Reverse

Name: bceS

Synonym: BSU30390

Alternate gene names: 16080091

Gene position: 3113194-3112190 (Counterclockwise)

Preceding gene: 16080092

Following gene: 16080090

Centisome position: 73.85

GC content: 42.39

Gene sequence:

>1005_bases
ATGATTAAAGCATTCCTTATCGAAAGGCGGAGCTGGATTGCCGCGTTTTTGTTTCAGCAGGCTTTGATGCTGTTCATTGC
TTTTGTCGATCCTTCCATATCATTTGGGAATGTACTTTATATGGTGTATTTGTGCATCTTGTTTTTTATCATATTCCTTT
GGTTCCGCTATCGGAAAGAAACAGCGTTTTATAAAAGCTTGAAAACATGGGAGAACAATCTCGATGTGACAGCCATAAAT
GAACCGGAAACGCCGTTTGAAGCAATGGTTGAAAGAAGCATTGCCGGGCAAACAGAACACTTGAAGCAGACCGCAGCACG
GCATCGCTTAGCATTGGAAAATGAAAAAGATGAGCTGATGGCATGGATCCATGAGGTCAAAACTCCATTAACAGCGATGC
ATTTAATCATTGATAGAATGGAAGAAAAAGCACTGAAATCCCAGCTGTCATATGAATGGCTGCGTATTCACCTGCTTCTT
GATCAGCAGCTTCATCAAAAACGCATTTCATTTATTGAAAACGACCTGTCAGTAGAATTCATTCAGCTTCAGCCTTTGAT
CTTTAAAGAAATCAAAGATTTACAATCGTGGTGTATCCAAAAAGGGATCGGTTTTGACATACAGCTCGAGGCCAAAGAAG
TGCTGAGCGATGCAAAATGGCTGGCGTTTATCATCAGGCAGCTGCTGACAAACGCGGTGAAATACAGCGAAGCCTCTGAA
ATCGAGATCAAAAGCTTTCAAAAAGGGGAACAGACGCAGCTCCAAGTGAAAGATTGTGGCAGGGGCATTGATCCAAAAGA
TGTACCGCGTATTTTTGATAAAGGGTTTACATCCACAACGGATCACCATGATCAAGCGTCAACTGGCATGGGGCTGTACT
TGGCAAAAAAAGCAGCGGCGCCGTTATTGATCCATATTGATGTTGAGTCGGAGTTTGGTGCGGGAACAGTTTTTACATTA
ACCTTTCCAATACGGAATCAATTTGAACATGTCATAAGCGTGTGA

Upstream 100 bases:

>100_bases
GTCAATCGCCTGCGAAAAAAACTGGACGCCCTGCAGCTTGGTGCATATATCGAGACAAAGGTGGGCCAGGGCTACATCGC
GAAGGAAGAGGACAAGTTCT

Downstream 100 bases:

>100_bases
CGAAAATGTCACATGCTTTTCTTTTTTGTTCGCCGTATCGAAGGAAAAGCCCGGCATTCCTTTTTATAATGAGATTATCC
AATATAAAGGAGACTGCGTA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIKAFLIERRSWIAAFLFQQALMLFIAFVDPSISFGNVLYMVYLCILFFIIFLWFRYRKETAFYKSLKTWENNLDVTAIN
EPETPFEAMVERSIAGQTEHLKQTAARHRLALENEKDELMAWIHEVKTPLTAMHLIIDRMEEKALKSQLSYEWLRIHLLL
DQQLHQKRISFIENDLSVEFIQLQPLIFKEIKDLQSWCIQKGIGFDIQLEAKEVLSDAKWLAFIIRQLLTNAVKYSEASE
IEIKSFQKGEQTQLQVKDCGRGIDPKDVPRIFDKGFTSTTDHHDQASTGMGLYLAKKAAAPLLIHIDVESEFGAGTVFTL
TFPIRNQFEHVISV

Sequences:

>Translated_334_residues
MIKAFLIERRSWIAAFLFQQALMLFIAFVDPSISFGNVLYMVYLCILFFIIFLWFRYRKETAFYKSLKTWENNLDVTAIN
EPETPFEAMVERSIAGQTEHLKQTAARHRLALENEKDELMAWIHEVKTPLTAMHLIIDRMEEKALKSQLSYEWLRIHLLL
DQQLHQKRISFIENDLSVEFIQLQPLIFKEIKDLQSWCIQKGIGFDIQLEAKEVLSDAKWLAFIIRQLLTNAVKYSEASE
IEIKSFQKGEQTQLQVKDCGRGIDPKDVPRIFDKGFTSTTDHHDQASTGMGLYLAKKAAAPLLIHIDVESEFGAGTVFTL
TFPIRNQFEHVISV
>Mature_334_residues
MIKAFLIERRSWIAAFLFQQALMLFIAFVDPSISFGNVLYMVYLCILFFIIFLWFRYRKETAFYKSLKTWENNLDVTAIN
EPETPFEAMVERSIAGQTEHLKQTAARHRLALENEKDELMAWIHEVKTPLTAMHLIIDRMEEKALKSQLSYEWLRIHLLL
DQQLHQKRISFIENDLSVEFIQLQPLIFKEIKDLQSWCIQKGIGFDIQLEAKEVLSDAKWLAFIIRQLLTNAVKYSEASE
IEIKSFQKGEQTQLQVKDCGRGIDPKDVPRIFDKGFTSTTDHHDQASTGMGLYLAKKAAAPLLIHIDVESEFGAGTVFTL
TFPIRNQFEHVISV

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=24.3801652892562, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BCES_BACSU (O35044)

Other databases:

- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   H70000
- RefSeq:   NP_390917.1
- ProteinModelPortal:   O35044
- SMR:   O35044
- EnsemblBacteria:   EBBACT00000001576
- GeneID:   936816
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU30390
- NMPDR:   fig|224308.1.peg.3042
- GenoList:   BSU30390
- GeneTree:   EBGT00070000032037
- HOGENOM:   HBG305212
- OMA:   YEWLRIH
- ProtClustDB:   CLSK873747
- BioCyc:   BSUB:BSU30390-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF02518 HATPase_c; SSF55874 ATP_bd_ATPase

EC number: =2.7.13.3

Molecular weight: Translated: 38765; Mature: 38765

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1054beac)-; HASH(0x11a65c3c)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAFLIERRSWIAAFLFQQALMLFIAFVDPSISFGNVLYMVYLCILFFIIFLWFRYRKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFYKSLKTWENNLDVTAINEPETPFEAMVERSIAGQTEHLKQTAARHRLALENEKDELM
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
AWIHEVKTPLTAMHLIIDRMEEKALKSQLSYEWLRIHLLLDQQLHQKRISFIENDLSVEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IQLQPLIFKEIKDLQSWCIQKGIGFDIQLEAKEVLSDAKWLAFIIRQLLTNAVKYSEASE
EEECHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IEIKSFQKGEQTQLQVKDCGRGIDPKDVPRIFDKGFTSTTDHHDQASTGMGLYLAKKAAA
CCHHHHCCCCCCEEEHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCEEEHHCCC
PLLIHIDVESEFGAGTVFTLTFPIRNQFEHVISV
CEEEEEEECCCCCCCEEEEEEECHHHHHHHHHCH
>Mature Secondary Structure
MIKAFLIERRSWIAAFLFQQALMLFIAFVDPSISFGNVLYMVYLCILFFIIFLWFRYRKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFYKSLKTWENNLDVTAINEPETPFEAMVERSIAGQTEHLKQTAARHRLALENEKDELM
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
AWIHEVKTPLTAMHLIIDRMEEKALKSQLSYEWLRIHLLLDQQLHQKRISFIENDLSVEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IQLQPLIFKEIKDLQSWCIQKGIGFDIQLEAKEVLSDAKWLAFIIRQLLTNAVKYSEASE
EEECHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IEIKSFQKGEQTQLQVKDCGRGIDPKDVPRIFDKGFTSTTDHHDQASTGMGLYLAKKAAA
CCHHHHCCCCCCEEEHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCEEEHHCCC
PLLIHIDVESEFGAGTVFTLTFPIRNQFEHVISV
CEEEEEEECCCCCCCEEEEEEECHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 14612242; 12890034