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The map label for this gene is tcyM

Identifier: 16079987

GI number: 16079987

Start: 3005122

End: 3005829

Strand: Reverse

Name: tcyM

Synonym: BSU29350

Alternate gene names: 16079987

Gene position: 3005829-3005122 (Counterclockwise)

Preceding gene: 16079988

Following gene: 16079986

Centisome position: 71.3

GC content: 43.93

Gene sequence:

>708_bases
TTGCAATTTGACTTTCCATTTATCGTTTCCGCCATGAAAGAAATGGTAAAGACCATTCCTCTGACATTGATGATGGCTGT
TTTGCCGATTGTGTTTGGATTTCTCGTGGCTCTTGGAAATATAATTGTTAGAATTTTTAGAATTAAGGGCTTGGTGGCTT
GCTCAAGGTTTTATGTGTCTTTCTTTCGAAGTACACCTGCAATTCTTCACATTATGTTGATTTATTTAGGGATACCGCCT
GTTGCAGATCAAGTCAGCAGTTTTTTTCATCTCGGCTGGTCCGCTAATGAGATACCGGTCTCCATGTTTGTCATCATGGC
CTTGTCTTTAACTGCCGGAGCTTATCTCACAGAAATCATCCGGTCGGGCATTCTGGCGATGGATACCGGACAGGTCGAAG
CGGCTTATTCAATCGGCTTGACATACAGCCAAACCTTTCGGCGTGTAATATTGCCGCAGGCGCTGAAGGTTTCCATCCCA
AACTTCACAAATTTGGGTATCGGCTTTTTGCATACCACCTCTATCGCGGCTATAGTGGCTGTCCCAGAGATTACAGGGAC
GGCGACTATCGTTGCTTCTGATAATTATGCATTTTTAGAAGCGTTTATCGGAGCAGCGATTATCTATTGGGTGCTGACTC
TAATCCTAGAATCCGCAAATGGAGTATTAGAGAGAAAGGCAGCCAGATTTCAAGGAGGCACTTTATGA

Upstream 100 bases:

>100_bases
GAGTGGCAGAAAAACGAATCAAGAAGAATCAAACAAGGATTGTTACTGTTTTTGACATGAACATACATTGATATATTTCT
TCGGATGAGGGGGGAGAAGA

Downstream 100 bases:

>100_bases
TTGAGATTAAAAATATCCATAAACAGTTTGGCATCCACCATGTATTAAAAGGGATAAATCTCACGGTACGCAAGGGAGAA
GTTGTGACGATTATCGGGCC

Product: sulfur-containing amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQFDFPFIVSAMKEMVKTIPLTLMMAVLPIVFGFLVALGNIIVRIFRIKGLVACSRFYVSFFRSTPAILHIMLIYLGIPP
VADQVSSFFHLGWSANEIPVSMFVIMALSLTAGAYLTEIIRSGILAMDTGQVEAAYSIGLTYSQTFRRVILPQALKVSIP
NFTNLGIGFLHTTSIAAIVAVPEITGTATIVASDNYAFLEAFIGAAIIYWVLTLILESANGVLERKAARFQGGTL

Sequences:

>Translated_235_residues
MQFDFPFIVSAMKEMVKTIPLTLMMAVLPIVFGFLVALGNIIVRIFRIKGLVACSRFYVSFFRSTPAILHIMLIYLGIPP
VADQVSSFFHLGWSANEIPVSMFVIMALSLTAGAYLTEIIRSGILAMDTGQVEAAYSIGLTYSQTFRRVILPQALKVSIP
NFTNLGIGFLHTTSIAAIVAVPEITGTATIVASDNYAFLEAFIGAAIIYWVLTLILESANGVLERKAARFQGGTL
>Mature_235_residues
MQFDFPFIVSAMKEMVKTIPLTLMMAVLPIVFGFLVALGNIIVRIFRIKGLVACSRFYVSFFRSTPAILHIMLIYLGIPP
VADQVSSFFHLGWSANEIPVSMFVIMALSLTAGAYLTEIIRSGILAMDTGQVEAAYSIGLTYSQTFRRVILPQALKVSIP
NFTNLGIGFLHTTSIAAIVAVPEITGTATIVASDNYAFLEAFIGAAIIYWVLTLILESANGVLERKAARFQGGTL

Specific function: Part of the ABC transporter complex tcyJKLMN involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine, djenkolate, and S-methylcysteine transport

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1788226, Length=229, Percent_Identity=32.3144104803493, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786873, Length=228, Percent_Identity=27.6315789473684, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787030, Length=230, Percent_Identity=27.8260869565217, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788645, Length=216, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787086, Length=226, Percent_Identity=26.9911504424779, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787087, Length=222, Percent_Identity=24.3243243243243, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082239, Length=218, Percent_Identity=28.8990825688073, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788646, Length=214, Percent_Identity=25.7009345794392, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI48994930, Length=87, Percent_Identity=42.5287356321839, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786874, Length=207, Percent_Identity=24.6376811594203, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TCYM_BACSU (O34931)

Other databases:

- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   G69996
- RefSeq:   NP_390813.1
- ProteinModelPortal:   O34931
- EnsemblBacteria:   EBBACT00000000321
- GeneID:   935938
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU29350
- NMPDR:   fig|224308.1.peg.2938
- GenoList:   BSU29350
- GeneTree:   EBGT00070000031979
- HOGENOM:   HBG704821
- OMA:   HLGWSAN
- ProtClustDB:   CLSK887715
- BioCyc:   BSUB:BSU29350-MONOMER
- InterPro:   IPR010065
- InterPro:   IPR000515
- TIGRFAMs:   TIGR01726

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 25594; Mature: 25594

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x119bb1a0)-; HASH(0x11559d3c)-; HASH(0x11902458)-; HASH(0x114a90f4)-; HASH(0x110e3058)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDFPFIVSAMKEMVKTIPLTLMMAVLPIVFGFLVALGNIIVRIFRIKGLVACSRFYVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFRSTPAILHIMLIYLGIPPVADQVSSFFHLGWSANEIPVSMFVIMALSLTAGAYLTEII
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RSGILAMDTGQVEAAYSIGLTYSQTFRRVILPQALKVSIPNFTNLGIGFLHTTSIAAIVA
HCCCEEEECCCCHHHHHCCCHHHHHHHHHHCCHHHHEECCCCCCCCHHHHHHHHHHHHHE
VPEITGTATIVASDNYAFLEAFIGAAIIYWVLTLILESANGVLERKAARFQGGTL
ECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCH
>Mature Secondary Structure
MQFDFPFIVSAMKEMVKTIPLTLMMAVLPIVFGFLVALGNIIVRIFRIKGLVACSRFYVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFRSTPAILHIMLIYLGIPPVADQVSSFFHLGWSANEIPVSMFVIMALSLTAGAYLTEII
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RSGILAMDTGQVEAAYSIGLTYSQTFRRVILPQALKVSIPNFTNLGIGFLHTTSIAAIVA
HCCCEEEECCCCHHHHHCCCHHHHHHHHHHCCHHHHEECCCCCCCCHHHHHHHHHHHHHE
VPEITGTATIVASDNYAFLEAFIGAAIIYWVLTLILESANGVLERKAARFQGGTL
ECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377