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The map label for this gene is infC

Identifier: 16079939

GI number: 16079939

Start: 2952828

End: 2953349

Strand: Reverse

Name: infC

Synonym: BSU28870

Alternate gene names: 16079939

Gene position: 2953349-2952828 (Counterclockwise)

Preceding gene: 16079942

Following gene: 16079938

Centisome position: 70.06

GC content: 43.87

Gene sequence:

>522_bases
ATTATTAGCAAAGATCAATTGGTTAATGAGGGTATCCGTGCACGTGAGGTCCGTTTAATCGGACAAAATGGCGACCAGCT
TGGAATCAAGTCCCGTCAGGAAGCACTTGAAATCGCCGGCCGCGCAAATCTTGACCTTGTGTTAGTTGCAGCGAATGCAA
AACCGCCTGTCTGCCGAATCATGGACTACGGTAAGTTCCGATTTGAGCAGCAGAAAAAGGAAAAAGAAGCACGCAAGAAT
CAAAAAATCATTAACTTAAAAGAAGTTCGGTTAAGTCCGACAATCGATGAGCATGACTTTAACACGAAATTGCGCAATGC
GATTAAATTCCTTGAAAAAGGCGATAAAGTGAAAGCTTCTATCCGCTTTAAAGGACGCGCAATCACTCATAAAGAAATCG
GTCAGCGTGTATTAGACCGTTTCTCCGAAGCATGTGCTGAGGTTGCGACAGTCGAAACAAAACCAAAAATGGACGGCCGC
AGCATGTTCTTAATGCTCGCACCGAAAAACGAAAAGCAATAA

Upstream 100 bases:

>100_bases
CGTAGTGTGGGTGTTTTATAATGCCCACACTTTTTGTTTGCCTGCAAAATGCATTCAAAATGAGTTGTGAATCAATTCGA
AGAAACTATGGAGGTGGCTC

Downstream 100 bases:

>100_bases
GGAGGAAATCCCATGCCAAAAATGAAAACTCACCGCGGATCTGCTAAACGTTTTAAAAAGACAGGTTCTGGGAAGTTAAA
ACGTTCTCACGCGTACACAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKFRFEQQKKEKEARKN
QKIINLKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGR
SMFLMLAPKNEKQ

Sequences:

>Translated_173_residues
MISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKFRFEQQKKEKEARKN
QKIINLKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGR
SMFLMLAPKNEKQ
>Mature_173_residues
MISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKFRFEQQKKEKEARKN
QKIINLKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGR
SMFLMLAPKNEKQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=52.760736196319, Blast_Score=161, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_BACSU (P55872)

Other databases:

- EMBL:   Z75208
- EMBL:   AL009126
- PIR:   H69644
- RefSeq:   NP_390765.1
- ProteinModelPortal:   P55872
- EnsemblBacteria:   EBBACT00000000048
- GeneID:   937835
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU28870
- NMPDR:   fig|224308.1.peg.2890
- GenoList:   BSU28870
- GeneTree:   EBGT00050000001839
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   BSUB:BSU28870-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 19732; Mature: 19732

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRI
CCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCEEEE
MDYGKFRFEQQKKEKEARKNQKIINLKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKAS
ECCCHHHHHHHHHHHHHHHCCCEEEHHHEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEE
IRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLMLAPKNEKQ
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRI
CCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCEEEE
MDYGKFRFEQQKKEKEARKNQKIINLKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKAS
ECCCHHHHHHHHHHHHHHHCCCEEEHHHEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEE
IRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLMLAPKNEKQ
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377