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The map label for this gene is rnhC

Identifier: 16079914

GI number: 16079914

Start: 2926031

End: 2926972

Strand: Direct

Name: rnhC

Synonym: BSU28620

Alternate gene names: 16079914

Gene position: 2926031-2926972 (Clockwise)

Preceding gene: 16079898

Following gene: 16079918

Centisome position: 69.41

GC content: 46.82

Gene sequence:

>942_bases
GTGTCCCATTCAGTGATAAAAGTATCGTTGTCTGCTATTGACCAAATGAAAATGACGTACAGCGGTTCACTTACAGCCTC
TGTTCCGCAGGGAGCCGTTTTTCAGGCAAAACCGCCCGGCTGTACCATTACAGCATATCAATCAGGTAAGGTCTTGTTTC
AAGGAAAAAACGCTGCGGCAGAATCCGCGCGCTGGGGAACAGCAGAGCCTCAGGAAAAGAAGAAAACGGCCAAAAAGCCG
GCTGATCCCCGCTATGCCCCTCCGGCAGATATCGCCGGAATGTCTGTTATCGGTTCTGACGAAGTCGGAACCGGAGATTA
CTTTGGCCCAATGACGGTTGTATGCGCGTACGTCGACAAAACCATGCTTCCTTTAATGAAGGAACTCGGTGTTAAGGATT
CTAAAGATTTAAAAGATCCGCAAATCATCGAGATTGCCCGAAACCTGATTAAAACCATTCCGTACAGCCTGCTGGTGTTA
AAGAATGAAAAGTATAACAGCATGCAGGAAAAAGGCATGAGCCAAGGGAAAATGAAAGCTTTGCTGCACAATCAGGCGAT
CACACATTTATTAAGAAAATTGGATGGAGTAAAGCCTGAAGCCATTTTGATTGACCAATTCGCTGAGCCAGGCGTCTACT
TCAATCATTTAAAGGGCAGAGACATTGTGAAGGAGCGGACCTATTTTAGCACAAAAGCTGAAGGTATTCACCTGGCTGTC
GCCGCTGCTTCAATCATTGCAAGATATTCATTTTTAATGGAAATGGATAAACTATCACGCGCGGCAGGAATGACGCTTCC
AAAAGGGGCCGGTCCGCACGTCGATGAAGCGGCCGCCAAGCTGATCCTCAAAAAAGGGGCATCTGCACTCAGAACCTTTA
CAAAACTCCATTTCGCCAATACGCAAAAAGCGCAGCGCCTTGCTGATAAAAAACGTTCATAG

Upstream 100 bases:

>100_bases
TTATCATAACACGTTTATTAAATGAATGGAAAGACGAGCCTCCCGCTGTTATGATACACTGGTATATACAGCGAAAAGTG
TAAAAAAAGGAGATTATTAC

Downstream 100 bases:

>100_bases
AAAAAAGCTTGCAGATTTCTCTGCAAGCTTTTTTATCAGCCTCTTAAAACAGCTTGATATGTGTCTTCTAACGCTTTCAG
CACTTTGCTGTGCGCCTTTG

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSHSVIKVSLSAIDQMKMTYSGSLTASVPQGAVFQAKPPGCTITAYQSGKVLFQGKNAAAESARWGTAEPQEKKKTAKKP
ADPRYAPPADIAGMSVIGSDEVGTGDYFGPMTVVCAYVDKTMLPLMKELGVKDSKDLKDPQIIEIARNLIKTIPYSLLVL
KNEKYNSMQEKGMSQGKMKALLHNQAITHLLRKLDGVKPEAILIDQFAEPGVYFNHLKGRDIVKERTYFSTKAEGIHLAV
AAASIIARYSFLMEMDKLSRAAGMTLPKGAGPHVDEAAAKLILKKGASALRTFTKLHFANTQKAQRLADKKRS

Sequences:

>Translated_313_residues
MSHSVIKVSLSAIDQMKMTYSGSLTASVPQGAVFQAKPPGCTITAYQSGKVLFQGKNAAAESARWGTAEPQEKKKTAKKP
ADPRYAPPADIAGMSVIGSDEVGTGDYFGPMTVVCAYVDKTMLPLMKELGVKDSKDLKDPQIIEIARNLIKTIPYSLLVL
KNEKYNSMQEKGMSQGKMKALLHNQAITHLLRKLDGVKPEAILIDQFAEPGVYFNHLKGRDIVKERTYFSTKAEGIHLAV
AAASIIARYSFLMEMDKLSRAAGMTLPKGAGPHVDEAAAKLILKKGASALRTFTKLHFANTQKAQRLADKKRS
>Mature_312_residues
SHSVIKVSLSAIDQMKMTYSGSLTASVPQGAVFQAKPPGCTITAYQSGKVLFQGKNAAAESARWGTAEPQEKKKTAKKPA
DPRYAPPADIAGMSVIGSDEVGTGDYFGPMTVVCAYVDKTMLPLMKELGVKDSKDLKDPQIIEIARNLIKTIPYSLLVLK
NEKYNSMQEKGMSQGKMKALLHNQAITHLLRKLDGVKPEAILIDQFAEPGVYFNHLKGRDIVKERTYFSTKAEGIHLAVA
AASIIARYSFLMEMDKLSRAAGMTLPKGAGPHVDEAAAKLILKKGASALRTFTKLHFANTQKAQRLADKKRS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH3_BACSU (P94541)

Other databases:

- EMBL:   Z75208
- EMBL:   AL009126
- PIR:   H69984
- RefSeq:   NP_390740.1
- ProteinModelPortal:   P94541
- SMR:   P94541
- EnsemblBacteria:   EBBACT00000002990
- GeneID:   937436
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU28620
- NMPDR:   fig|224308.1.peg.2865
- GenoList:   BSU28620
- GeneTree:   EBGT00050000000939
- HOGENOM:   HBG288559
- OMA:   ASIIARY
- ProtClustDB:   PRK00996
- BioCyc:   BSUB:BSU28620-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00053
- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337
- PIRSF:   PIRSF037748
- TIGRFAMs:   TIGR00716

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 34070; Mature: 33939

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSVIKVSLSAIDQMKMTYSGSLTASVPQGAVFQAKPPGCTITAYQSGKVLFQGKNAAA
CCCCEEEEEHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCEEEEECCCEEEEECCCCHH
ESARWGTAEPQEKKKTAKKPADPRYAPPADIAGMSVIGSDEVGTGDYFGPMTVVCAYVDK
HCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
TMLPLMKELGVKDSKDLKDPQIIEIARNLIKTIPYSLLVLKNEKYNSMQEKGMSQGKMKA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHH
LLHNQAITHLLRKLDGVKPEAILIDQFAEPGVYFNHLKGRDIVKERTYFSTKAEGIHLAV
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCCCCEEHHH
AAASIIARYSFLMEMDKLSRAAGMTLPKGAGPHVDEAAAKLILKKGASALRTFTKLHFAN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCC
TQKAQRLADKKRS
HHHHHHHHHHCCC
>Mature Secondary Structure 
SHSVIKVSLSAIDQMKMTYSGSLTASVPQGAVFQAKPPGCTITAYQSGKVLFQGKNAAA
CCCEEEEEHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCEEEEECCCEEEEECCCCHH
ESARWGTAEPQEKKKTAKKPADPRYAPPADIAGMSVIGSDEVGTGDYFGPMTVVCAYVDK
HCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
TMLPLMKELGVKDSKDLKDPQIIEIARNLIKTIPYSLLVLKNEKYNSMQEKGMSQGKMKA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHH
LLHNQAITHLLRKLDGVKPEAILIDQFAEPGVYFNHLKGRDIVKERTYFSTKAEGIHLAV
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCCCCEEHHH
AAASIIARYSFLMEMDKLSRAAGMTLPKGAGPHVDEAAAKLILKKGASALRTFTKLHFAN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCC
TQKAQRLADKKRS
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377; 10094689; 9888800