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The map label for this gene is mreD

Identifier: 16079853

GI number: 16079853

Start: 2859317

End: 2859835

Strand: Reverse

Name: mreD

Synonym: BSU28010

Alternate gene names: 16079853

Gene position: 2859835-2859317 (Counterclockwise)

Preceding gene: 255767641

Following gene: 16079852

Centisome position: 67.84

GC content: 36.61

Gene sequence:

>519_bases
GTGAAACGTTTCCTTCTCCCTTTCGTTATGATGCTTGTTTTTTCTGCGGAAAGCATTTTTACAGATTTGGTGCATTTTCC
TTTCGTTACAGATGACCAAGTGCTCGCCCCGCGTTTTTTGATGCTTGTATTGATATTCATGTCGGCTTTTATCAACCAAA
AACACGCGATGATTTACGGATTTATTTTTGGCTTTCTATATGACATGAACTATACAAGTCTATTAGGCGTTTACATGTTT
GGTTTTGCAGGGCTATGCTATTTGGCTTCAAAAGCGTTTAAAGTGTTGCATACAAACGCATTTGTAGTGATATTGATAGC
AGTTCTGGCTGTCTGTCTGCTCGAATTTTACGTATTCGGCATTCAGTCTTTGATTCATAAAGACATTATGACGTTTAACG
GATTTGTGCTTGACCGGTTTATACCGACAATTTTATTAAATATTGCAGCAGCTCTTATTCTTGTTCTGCCATTTAGATTG
TTTTTTATGAGTCTAAAGAAAGAATTGAGAGATGAGTAA

Upstream 100 bases:

>100_bases
AGGTTGCTTATGTAAAACCTGCGGCTGACCTTACAGATTTAAATAATGTGATCGTTGTTAACCGTGACGTGCCGACTGTC
GATACAGAGGAGGAAGGATC

Downstream 100 bases:

>100_bases
AAAGGATTTTATCTTTTTTTGACGAAATGAGTATGTTGTTGAGGTGAATATTGTGAAGACCAAAAAGCAGCAATATGTAA
CAATAAAAGGAACAAAGAAT

Product: cell-shape determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKRFLLPFVMMLVFSAESIFTDLVHFPFVTDDQVLAPRFLMLVLIFMSAFINQKHAMIYGFIFGFLYDMNYTSLLGVYMF
GFAGLCYLASKAFKVLHTNAFVVILIAVLAVCLLEFYVFGIQSLIHKDIMTFNGFVLDRFIPTILLNIAAALILVLPFRL
FFMSLKKELRDE

Sequences:

>Translated_172_residues
MKRFLLPFVMMLVFSAESIFTDLVHFPFVTDDQVLAPRFLMLVLIFMSAFINQKHAMIYGFIFGFLYDMNYTSLLGVYMF
GFAGLCYLASKAFKVLHTNAFVVILIAVLAVCLLEFYVFGIQSLIHKDIMTFNGFVLDRFIPTILLNIAAALILVLPFRL
FFMSLKKELRDE
>Mature_172_residues
MKRFLLPFVMMLVFSAESIFTDLVHFPFVTDDQVLAPRFLMLVLIFMSAFINQKHAMIYGFIFGFLYDMNYTSLLGVYMF
GFAGLCYLASKAFKVLHTNAFVVILIAVLAVCLLEFYVFGIQSLIHKDIMTFNGFVLDRFIPTILLNIAAALILVLPFRL
FFMSLKKELRDE

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRED_BACSU (Q01467)

Other databases:

- EMBL:   M95582
- EMBL:   M96343
- EMBL:   AL009126
- PIR:   E45239
- RefSeq:   NP_390679.1
- ProteinModelPortal:   Q01467
- EnsemblBacteria:   EBBACT00000000134
- GeneID:   936183
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU28010
- NMPDR:   fig|224308.1.peg.2804
- GenoList:   BSU28010
- GeneTree:   EBGT00050000003001
- HOGENOM:   HBG533108
- OMA:   YMFGFAG
- ProtClustDB:   CLSK887682
- BioCyc:   BSUB:BSU28010-MONOMER
- InterPro:   IPR007227
- TIGRFAMs:   TIGR03426

Pfam domain/function: PF04093 MreD

EC number: NA

Molecular weight: Translated: 19816; Mature: 19816

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfab9214)-; HASH(0xd2e2c10)-; HASH(0xfdb9a00)-; HASH(0x10d05720)-; HASH(0x1173165c)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFLLPFVMMLVFSAESIFTDLVHFPFVTDDQVLAPRFLMLVLIFMSAFINQKHAMIYG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
FIFGFLYDMNYTSLLGVYMFGFAGLCYLASKAFKVLHTNAFVVILIAVLAVCLLEFYVFG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQSLIHKDIMTFNGFVLDRFIPTILLNIAAALILVLPFRLFFMSLKKELRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MKRFLLPFVMMLVFSAESIFTDLVHFPFVTDDQVLAPRFLMLVLIFMSAFINQKHAMIYG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
FIFGFLYDMNYTSLLGVYMFGFAGLCYLASKAFKVLHTNAFVVILIAVLAVCLLEFYVFG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQSLIHKDIMTFNGFVLDRFIPTILLNIAAALILVLPFRLFFMSLKKELRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377