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The map label for this gene is obgE

Identifier: 16079844

GI number: 16079844

Start: 2852661

End: 2853947

Strand: Reverse

Name: obgE

Synonym: BSU27920

Alternate gene names: 16079844

Gene position: 2853947-2852661 (Counterclockwise)

Preceding gene: 16079845

Following gene: 16079843

Centisome position: 67.7

GC content: 48.41

Gene sequence:

>1287_bases
ATGTTTGTAGATCAGGTCAAAGTATATGTAAAAGGCGGCGACGGCGGCAACGGTATGGTTGCGTTTCGCCGTGAAAAATA
TGTGCCGAAAGGCGGCCCTGCCGGCGGTGACGGAGGAAAGGGAGGAGACGTCGTTTTTGAAGTAGATGAAGGTCTCCGCA
CCCTGATGGATTTTAGATACAAAAAACACTTTAAAGCGATTCGCGGCGAGCATGGCATGTCCAAAAACCAGCACGGGCGA
AATGCTGATGATATGGTCATTAAAGTTCCGCCGGGCACCGTTGTGACAGACGATGATACAAAACAGGTCATCGCTGATTT
AACAGAGCACGGACAGCGGGCTGTCATTGCAAGAGGCGGAAGAGGCGGAAGAGGAAATAGCCGCTTTGCTACACCGGCTA
ATCCCGCGCCTCAGCTTTCAGAAAACGGCGAGCCGGGAAAAGAACGCTACATTGTTCTTGAATTAAAAGTGCTTGCAGAT
GTCGGACTTGTCGGGTTCCCGAGTGTGGGAAAATCTACTTTGCTGTCTGTTGTCTCATCTGCAAAACCGAAAATTGCGGA
CTATCACTTTACAACGCTTGTCCCGAATCTCGGCATGGTTGAAACGGATGACGGACGCAGCTTTGTCATGGCTGATTTGC
CAGGGCTGATTGAAGGCGCACACCAAGGCGTCGGACTGGGCCACCAGTTTTTGCGCCATATTGAACGGACGAGGGTTATT
GTTCATGTCATTGACATGTCAGGCTTAGAAGGCCGTGATCCATATGATGATTATCTTACGATTAACCAGGAGCTGAGCGA
GTACAATCTGCGTCTCACTGAGCGTCCGCAAATTATCGTTGCAAATAAAATGGACATGCCGGAGGCTGCGGAAAATCTCG
AAGCCTTTAAAGAAAAGCTGACGGATGATTATCCGGTATTCCCGATCAGTGCGGTGACAAGAGAAGGTCTGCGTGAGCTT
CTGTTTGAGGTTGCCAATCAGCTTGAGAACACACCGGAATTCCCGCTGTATGACGAGGAAGAGCTTACACAAAACCGTGT
CATGTACACGATGGAAAATGAAGAAGTGCCATTTAACATTACACGCGATCCAGACGGTGTATTTGTGCTTTCAGGAGACA
GCCTTGAGCGGTTATTCAAGATGACTGATTTCTCACGTGATGAATCGGTTAAACGGTTTGCAAGACAGATGCGCGGAATG
GGTGTTGATGAAGCACTCAGAGAACGCGGAGCCAAGGATGGAGATATAATCAGGCTTCTGGAATTTGAATTTGAATTTAT
TGATTAA

Upstream 100 bases:

>100_bases
GGACGTTGATATCATGCGTTTTGAAATCACGAGTCACGAATGTCTGATTGAAATTGGGTTGGACTAGCGGAGTTTTTAAC
GGTTTAGAACGGAGGACATT

Downstream 100 bases:

>100_bases
TCAATGTTGGCTGAAAAGAGAGCCTGGTGCCAGGCTCTCTATTTTAAAGGGGGGATGCAAATGAAAGAGGAGACATTTTA
TCTTGTCCGTGAAGATGTAT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFEVDEGLRTLMDFRYKKHFKAIRGEHGMSKNQHGR
NADDMVIKVPPGTVVTDDDTKQVIADLTEHGQRAVIARGGRGGRGNSRFATPANPAPQLSENGEPGKERYIVLELKVLAD
VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHQGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYDDYLTINQELSEYNLRLTERPQIIVANKMDMPEAAENLEAFKEKLTDDYPVFPISAVTREGLREL
LFEVANQLENTPEFPLYDEEELTQNRVMYTMENEEVPFNITRDPDGVFVLSGDSLERLFKMTDFSRDESVKRFARQMRGM
GVDEALRERGAKDGDIIRLLEFEFEFID

Sequences:

>Translated_428_residues
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFEVDEGLRTLMDFRYKKHFKAIRGEHGMSKNQHGR
NADDMVIKVPPGTVVTDDDTKQVIADLTEHGQRAVIARGGRGGRGNSRFATPANPAPQLSENGEPGKERYIVLELKVLAD
VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHQGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYDDYLTINQELSEYNLRLTERPQIIVANKMDMPEAAENLEAFKEKLTDDYPVFPISAVTREGLREL
LFEVANQLENTPEFPLYDEEELTQNRVMYTMENEEVPFNITRDPDGVFVLSGDSLERLFKMTDFSRDESVKRFARQMRGM
GVDEALRERGAKDGDIIRLLEFEFEFID
>Mature_428_residues
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFEVDEGLRTLMDFRYKKHFKAIRGEHGMSKNQHGR
NADDMVIKVPPGTVVTDDDTKQVIADLTEHGQRAVIARGGRGGRGNSRFATPANPAPQLSENGEPGKERYIVLELKVLAD
VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHQGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYDDYLTINQELSEYNLRLTERPQIIVANKMDMPEAAENLEAFKEKLTDDYPVFPISAVTREGLREL
LFEVANQLENTPEFPLYDEEELTQNRVMYTMENEEVPFNITRDPDGVFVLSGDSLERLFKMTDFSRDESVKRFARQMRGM
GVDEALRERGAKDGDIIRLLEFEFEFID

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=345, Percent_Identity=42.0289855072464, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI111955139, Length=391, Percent_Identity=35.8056265984655, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI111955063, Length=260, Percent_Identity=37.6923076923077, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=38.8429752066116, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=37.7952755905512, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789574, Length=346, Percent_Identity=48.2658959537572, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=34.7826086956522, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17508313, Length=329, Percent_Identity=41.0334346504559, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17552324, Length=303, Percent_Identity=32.3432343234323, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=38.9830508474576, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=36.4406779661017, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=30.2158273381295, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=195, Percent_Identity=37.9487179487179, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=39.6825396825397, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=35.7142857142857, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129375, Length=324, Percent_Identity=43.2098765432099, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24585318, Length=309, Percent_Identity=40.453074433657, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21356473, Length=126, Percent_Identity=38.8888888888889, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=37.007874015748, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47690; Mature: 47690

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFEVDEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHH
KKHFKAIRGEHGMSKNQHGRNADDMVIKVPPGTVVTDDDTKQVIADLTEHGQRAVIARGG
HHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATPANPAPQLSENGEPGKERYIVLELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHCCCCCCCCCCHHHHHHHHHH
AKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHQGVGLGHQFLRHIERTRVI
CCCCCCCEEHHHHCCCCCCEECCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYDDYLTINQELSEYNLRLTERPQIIVANKMDMPEAAENLEAFKEKL
EEEEECCCCCCCCCCCHHEEECCHHHHCCCEEECCCCEEEECCCCCCHHHHHHHHHHHHC
TDDYPVFPISAVTREGLRELLFEVANQLENTPEFPLYDEEELTQNRVMYTMENEEVPFNI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEECCCCCCEEE
TRDPDGVFVLSGDSLERLFKMTDFSRDESVKRFARQMRGMGVDEALRERGAKDGDIIRLL
ECCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EFEFEFID
EEEEEECC
>Mature Secondary Structure
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFEVDEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHH
KKHFKAIRGEHGMSKNQHGRNADDMVIKVPPGTVVTDDDTKQVIADLTEHGQRAVIARGG
HHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATPANPAPQLSENGEPGKERYIVLELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHCCCCCCCCCCHHHHHHHHHH
AKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHQGVGLGHQFLRHIERTRVI
CCCCCCCEEHHHHCCCCCCEECCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYDDYLTINQELSEYNLRLTERPQIIVANKMDMPEAAENLEAFKEKL
EEEEECCCCCCCCCCCHHEEECCHHHHCCCEEECCCCEEEECCCCCCHHHHHHHHHHHHC
TDDYPVFPISAVTREGLRELLFEVANQLENTPEFPLYDEEELTQNRVMYTMENEEVPFNI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEECCCCCCEEE
TRDPDGVFVLSGDSLERLFKMTDFSRDESVKRFARQMRGMGVDEALRERGAKDGDIIRLL
ECCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EFEFEFID
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA