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The map label for this gene is pheA

Identifier: 16079842

GI number: 16079842

Start: 2851283

End: 2852140

Strand: Reverse

Name: pheA

Synonym: BSU27900

Alternate gene names: 16079842

Gene position: 2852140-2851283 (Counterclockwise)

Preceding gene: 16079843

Following gene: 16079839

Centisome position: 67.66

GC content: 43.01

Gene sequence:

>858_bases
ATGAAAGTCGGTTATTTAGGTCCAGCAGCTACATTTACACATCTAGCAGTCAGTTCTTGTTTTCAAAACGGCGCCGAACA
TGTTGCTTACCGCACCATTCCGGAGTGTATAGATGCAGCCGTTGCAGGCGAAGTTGATTTTGCTTTTGTTCCTTTGGAAA
ATGCTTTAGAAGGATCTGTTAATCTAACAATAGACTATTTAATACATGAACAGCCTTTGCCAATCGTGGGTGAAATGACG
TTGCCGATTCACCAGCACTTGCTCGTCCATCCCTCAAGAGAGAATGCATGGAAAGAGCTCGACAAAATTTACTCACATTC
ACACGCGATTGCGCAATGCCATAAATTTCTTCATCGACATTTTCCTTCCGTTCCATATGAATACGCCAATTCTACCGGGG
CGGCAGCAAAGTTTGTCAGTGACCATCCCGAGCTGAATATCGGGGTCATTGCCAATGATATGGCAGCTTCTACATACGAA
TTAAAAATCGTGAAACGGGATATACAGGATTATAGGGACAATCATACAAGATTTGTTATCCTGTCTCCCGATGAAAACAT
ATCTTTTGAAGTGAATTCAAAATTGAGCTCTAGGCCCAAAACGACCTTAATGGTCATGCTGCCGCAGGATGATCAGTCCG
GGGCGCTGCATAGAGTGCTGTCTGCATTTTCTTGGAGAAATTTAAACCTGTCAAAAATTGAGTCACGTCCGACTAAAACC
GGATTAGGCCATTATTTCTTTATTATTGATATTGAGAAAGCGTTTGATGATGTATTGATTCCAGGGGCCATGCAGGAGCT
TGAAGCACTCGGCTGCAAAGTGAGGCTTCTGGGTGCATACCAGTCTTACCAATTATAA

Upstream 100 bases:

>100_bases
GAAGAAGACATTCATACATTAATGAATAAGCTCAGGAAGTTTGATTTTGTAGAAAAGGTTGAAATATTAGGTTCAGGTGC
ATAAGGGAGAGAAAATCGTC

Downstream 100 bases:

>100_bases
AAAAAGCCCACTAGAGGGCTTTTTTTAGTCTTTAATTAAAATGCCGGCTTCTTCGAGGGCTTGGCAGGCTTGATCGATGC
GATGTTCATCAGGTGCTGTC

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKVGYLGPAATFTHLAVSSCFQNGAEHVAYRTIPECIDAAVAGEVDFAFVPLENALEGSVNLTIDYLIHEQPLPIVGEMT
LPIHQHLLVHPSRENAWKELDKIYSHSHAIAQCHKFLHRHFPSVPYEYANSTGAAAKFVSDHPELNIGVIANDMAASTYE
LKIVKRDIQDYRDNHTRFVILSPDENISFEVNSKLSSRPKTTLMVMLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
GLGHYFFIIDIEKAFDDVLIPGAMQELEALGCKVRLLGAYQSYQL

Sequences:

>Translated_285_residues
MKVGYLGPAATFTHLAVSSCFQNGAEHVAYRTIPECIDAAVAGEVDFAFVPLENALEGSVNLTIDYLIHEQPLPIVGEMT
LPIHQHLLVHPSRENAWKELDKIYSHSHAIAQCHKFLHRHFPSVPYEYANSTGAAAKFVSDHPELNIGVIANDMAASTYE
LKIVKRDIQDYRDNHTRFVILSPDENISFEVNSKLSSRPKTTLMVMLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
GLGHYFFIIDIEKAFDDVLIPGAMQELEALGCKVRLLGAYQSYQL
>Mature_285_residues
MKVGYLGPAATFTHLAVSSCFQNGAEHVAYRTIPECIDAAVAGEVDFAFVPLENALEGSVNLTIDYLIHEQPLPIVGEMT
LPIHQHLLVHPSRENAWKELDKIYSHSHAIAQCHKFLHRHFPSVPYEYANSTGAAAKFVSDHPELNIGVIANDMAASTYE
LKIVKRDIQDYRDNHTRFVILSPDENISFEVNSKLSSRPKTTLMVMLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
GLGHYFFIIDIEKAFDDVLIPGAMQELEALGCKVRLLGAYQSYQL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain

Homologues:

Organism=Escherichia coli, GI1788951, Length=293, Percent_Identity=31.0580204778157, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHEA_BACSU (P21203)

Other databases:

- EMBL:   M24537
- EMBL:   AL009126
- EMBL:   M98822
- PIR:   C32804
- RefSeq:   NP_390668.1
- ProteinModelPortal:   P21203
- SMR:   P21203
- EnsemblBacteria:   EBBACT00000002971
- GeneID:   937513
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU27900
- NMPDR:   fig|224308.1.peg.2793
- GenoList:   BSU27900
- GeneTree:   EBGT00050000001546
- HOGENOM:   HBG693866
- OMA:   CRKWLDA
- PhylomeDB:   P21203
- ProtClustDB:   PRK11898
- BioCyc:   BSUB:BSU27900-MONOMER
- BRENDA:   4.2.1.51
- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528

Pfam domain/function: PF01842 ACT; PF00800 PDT

EC number: =4.2.1.51

Molecular weight: Translated: 31902; Mature: 31902

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00857 PREPHENATE_DEHYDR_1; PS00858 PREPHENATE_DEHYDR_2; PS51171 PREPHENATE_DEHYDR_3; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGYLGPAATFTHLAVSSCFQNGAEHVAYRTIPECIDAAVAGEVDFAFVPLENALEGSV
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHCCCCE
NLTIDYLIHEQPLPIVGEMTLPIHQHLLVHPSRENAWKELDKIYSHSHAIAQCHKFLHRH
EEEEEEEEECCCCCEECCEECCCHHHEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHH
FPSVPYEYANSTGAAAKFVSDHPELNIGVIANDMAASTYELKIVKRDIQDYRDNHTRFVI
CCCCCHHHCCCCCCHHHHHCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCEEEE
LSPDENISFEVNSKLSSRPKTTLMVMLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
ECCCCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCC
GLGHYFFIIDIEKAFDDVLIPGAMQELEALGCKVRLLGAYQSYQL
CCCEEEEEEEEHHHHCHHCCCHHHHHHHHCCCEEEEEECHHCCCC
>Mature Secondary Structure
MKVGYLGPAATFTHLAVSSCFQNGAEHVAYRTIPECIDAAVAGEVDFAFVPLENALEGSV
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHCCCCE
NLTIDYLIHEQPLPIVGEMTLPIHQHLLVHPSRENAWKELDKIYSHSHAIAQCHKFLHRH
EEEEEEEEECCCCCEECCEECCCHHHEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHH
FPSVPYEYANSTGAAAKFVSDHPELNIGVIANDMAASTYELKIVKRDIQDYRDNHTRFVI
CCCCCHHHCCCCCCHHHHHCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCEEEE
LSPDENISFEVNSKLSSRPKTTLMVMLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
ECCCCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCC
GLGHYFFIIDIEKAFDDVLIPGAMQELEALGCKVRLLGAYQSYQL
CCCEEEEEEEEHHHHCHHCCCHHHHHHHHCCCEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2537815; 9384377; 8444804