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The map label for this gene is yrhH

Identifier: 16079772

GI number: 16079772

Start: 2777877

End: 2778419

Strand: Reverse

Name: yrhH

Synonym: BSU27180

Alternate gene names: 16079772

Gene position: 2778419-2777877 (Counterclockwise)

Preceding gene: 16079773

Following gene: 16079771

Centisome position: 65.91

GC content: 36.65

Gene sequence:

>543_bases
ATGCTAGAAAATAGACTCTATAAACGATCGGATTTTTGGAAATTATTTTCTCGGAAATATAAGCTAACCAAAACAATTGA
GCATATGATGATTGACTCTATAGATATACAAGAAAATGACAGAATTTTAGAAATTGGAATTGGAAACGGCACTGTCTTTA
AAAGCATAACCAAGAAACTAAAAAAGGGTAGCCTAAAAAGCATTGATCCTTCAAAACGAAAGGTAAGACAGATATCACGT
GCGAATCGAAAGAACATGGGGAACGGGGAGGTTTTTCATGGCTATCCAGAGGACATTCCCTTTGATGACCGTACCTTTAA
TAAAGTCTTTTCTTTACATACGGTTCAAAGCTGCACCGATATTAGGCTTGCATTAAGAGAAATTTACAGGGTGCTTCAAA
TTGACGGCCGGTTTTATATCAGTATTGACACAAATACCGGTGAAAAAGAGAAAACGTATATTCAACTGCTGAAAGACCAG
CATTTCAGGGATCTTTCTGTTATCAGGCGTGCTTCCTGTCTATGTATTGTGGCTGTTAAATAA

Upstream 100 bases:

>100_bases
GCCGTCTAGTTGGTACCTTCCTTCACTTTTAGAAATGAAGATGATGTTTATTTTTTTAAGATAATAAATAAACATAGGAA
ACCAAAAGCAGGTGTTTAAA

Downstream 100 bases:

>100_bases
AAAATTTCTCGGGAAATATATCCAAGATCCTCGTATTAGGATTTGGGTATATTTTCTTAATTTTTTATTTTTTGCATATA
CTTTATATTAAAAAAAGTTT

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MLENRLYKRSDFWKLFSRKYKLTKTIEHMMIDSIDIQENDRILEIGIGNGTVFKSITKKLKKGSLKSIDPSKRKVRQISR
ANRKNMGNGEVFHGYPEDIPFDDRTFNKVFSLHTVQSCTDIRLALREIYRVLQIDGRFYISIDTNTGEKEKTYIQLLKDQ
HFRDLSVIRRASCLCIVAVK

Sequences:

>Translated_180_residues
MLENRLYKRSDFWKLFSRKYKLTKTIEHMMIDSIDIQENDRILEIGIGNGTVFKSITKKLKKGSLKSIDPSKRKVRQISR
ANRKNMGNGEVFHGYPEDIPFDDRTFNKVFSLHTVQSCTDIRLALREIYRVLQIDGRFYISIDTNTGEKEKTYIQLLKDQ
HFRDLSVIRRASCLCIVAVK
>Mature_180_residues
MLENRLYKRSDFWKLFSRKYKLTKTIEHMMIDSIDIQENDRILEIGIGNGTVFKSITKKLKKGSLKSIDPSKRKVRQISR
ANRKNMGNGEVFHGYPEDIPFDDRTFNKVFSLHTVQSCTDIRLALREIYRVLQIDGRFYISIDTNTGEKEKTYIQLLKDQ
HFRDLSVIRRASCLCIVAVK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YRHH_BACSU (O05400)

Other databases:

- EMBL:   U93874
- EMBL:   AL009126
- PIR:   G69974
- RefSeq:   NP_390596.1
- ProteinModelPortal:   O05400
- SMR:   O05400
- EnsemblBacteria:   EBBACT00000002685
- GeneID:   938507
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU27180
- NMPDR:   fig|224308.1.peg.2721
- GenoList:   BSU27180
- GeneTree:   EBGT00050000000514
- HOGENOM:   HBG338198
- OMA:   YRVLQID
- ProtClustDB:   CLSK887653
- BioCyc:   BSUB:BSU27180-MONOMER
- InterPro:   IPR013216

Pfam domain/function: PF08241 Methyltransf_11

EC number: 2.1.1.- [C]

Molecular weight: Translated: 21137; Mature: 21137

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENRLYKRSDFWKLFSRKYKLTKTIEHMMIDSIDIQENDRILEIGIGNGTVFKSITKKL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHH
KKGSLKSIDPSKRKVRQISRANRKNMGNGEVFHGYPEDIPFDDRTFNKVFSLHTVQSCTD
HCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
IRLALREIYRVLQIDGRFYISIDTNTGEKEKTYIQLLKDQHFRDLSVIRRASCLCIVAVK
HHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCEEEEEEEC
>Mature Secondary Structure
MLENRLYKRSDFWKLFSRKYKLTKTIEHMMIDSIDIQENDRILEIGIGNGTVFKSITKKL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHH
KKGSLKSIDPSKRKVRQISRANRKNMGNGEVFHGYPEDIPFDDRTFNKVFSLHTVQSCTD
HCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
IRLALREIYRVLQIDGRFYISIDTNTGEKEKTYIQLLKDQHFRDLSVIRRASCLCIVAVK
HHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377