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The map label for this gene is yosS

Identifier: 16079060

GI number: 16079060

Start: 2159268

End: 2159696

Strand: Reverse

Name: yosS

Synonym: BSU20020

Alternate gene names: 16079060

Gene position: 2159696-2159268 (Counterclockwise)

Preceding gene: 16079061

Following gene: 16079059

Centisome position: 51.23

GC content: 41.49

Gene sequence:

>429_bases
ATGCAAATTAAAATCAAATACTTAGATGAAACACAAACAAGAATTAACAAAATGGAGCAAGGTGATTGGATTGATCTTCG
TGCAGCTGAAGATGTAGCGATCAAAAAAGATGAATTTAAACTTGTTCCATTGGGAGTGGCCATGGAATTGCCTGAAGGTT
ACGAAGCACATGTCGTTCCTCGTTCGAGTACGTATAAGAACTTTGGTGTGATTCAAACAAACTCAATGGGTGTTATCGAT
GAGTCTTATAAGGGTGACAACGATTTTTGGTTCTTTCCTGCTTATGCGTTACGTGACACAAAGATTAAGAAAGGGGATCG
AATCTGCCAGTTCAGAATTATGAAGAAGATGCCGGCAGTTGACTTGATCGAGGTAGACCGTCTAGGCAACGGTGACCGAG
GTGGGCACGGATCAACTGGAACGAAGTAA

Upstream 100 bases:

>100_bases
AAGTGTTGGTTTTAAGCCTAATGAACTTGATGAGTTACTAAAGGAATTACGATAAAAGGGTAATTTTAAACAAACTTGAA
TTAAAAGGAGCTAATACATA

Downstream 100 bases:

>100_bases
TTGGATTTTGTATTTGAAATATAGATTATTTTAAAAGTCATCTTGAAAAACATTTTTAATCATATTACCTTTTTCTAGGA
AAGGGGATTAAAATATGAAA

Product: SPbeta phage deoxyuridine 5'-triphosphate nucleotidohydrolase

Products: NA

Alternate protein names: dUTPase; dUTP pyrophosphatase [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MQIKIKYLDETQTRINKMEQGDWIDLRAAEDVAIKKDEFKLVPLGVAMELPEGYEAHVVPRSSTYKNFGVIQTNSMGVID
ESYKGDNDFWFFPAYALRDTKIKKGDRICQFRIMKKMPAVDLIEVDRLGNGDRGGHGSTGTK

Sequences:

>Translated_142_residues
MQIKIKYLDETQTRINKMEQGDWIDLRAAEDVAIKKDEFKLVPLGVAMELPEGYEAHVVPRSSTYKNFGVIQTNSMGVID
ESYKGDNDFWFFPAYALRDTKIKKGDRICQFRIMKKMPAVDLIEVDRLGNGDRGGHGSTGTK
>Mature_142_residues
MQIKIKYLDETQTRINKMEQGDWIDLRAAEDVAIKKDEFKLVPLGVAMELPEGYEAHVVPRSSTYKNFGVIQTNSMGVID
ESYKGDNDFWFFPAYALRDTKIKKGDRICQFRIMKKMPAVDLIEVDRLGNGDRGGHGSTGTK

Specific function: This enzyme is involved in nucleotide metabolism:it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA [H]

COG id: COG0756

COG function: function code F; dUTPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dUTPase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008180 [H]

Pfam domain/function: PF00692 dUTPase [H]

EC number: =3.6.1.23 [H]

Molecular weight: Translated: 16149; Mature: 16149

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKIKYLDETQTRINKMEQGDWIDLRAAEDVAIKKDEFKLVPLGVAMELPEGYEAHVVP
CEEEEEECCCHHHHHHHCCCCCEEEEECCCCEEEECCCEEEEEEEEEEECCCCCEEEEEE
RSSTYKNFGVIQTNSMGVIDESYKGDNDFWFFPAYALRDTKIKKGDRICQFRIMKKMPAV
CCCCCCCCCEEEECCCCCEECCCCCCCCEEEECCEEEECCCCCCCCCEEEEEEHHHCCCC
DLIEVDRLGNGDRGGHGSTGTK
CEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQIKIKYLDETQTRINKMEQGDWIDLRAAEDVAIKKDEFKLVPLGVAMELPEGYEAHVVP
CEEEEEECCCHHHHHHHCCCCCEEEEECCCCEEEECCCEEEEEEEEEEECCCCCEEEEEE
RSSTYKNFGVIQTNSMGVIDESYKGDNDFWFFPAYALRDTKIKKGDRICQFRIMKKMPAV
CCCCCCCCCEEEECCCCCEECCCCCCCCEEEECCEEEECCCCCCCCCEEEEEEHHHCCCC
DLIEVDRLGNGDRGGHGSTGTK
CEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]