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The map label for this gene is yodS

Identifier: 16079031

GI number: 16079031

Start: 2143660

End: 2144349

Strand: Reverse

Name: yodS

Synonym: BSU19730

Alternate gene names: 16079031

Gene position: 2144349-2143660 (Counterclockwise)

Preceding gene: 16079032

Following gene: 16079030

Centisome position: 50.87

GC content: 50.0

Gene sequence:

>690_bases
ATGGCGCCATTTCAAAAAGCAATCAGCATTGACACAGCAATTGCAGATGTTCGGGATGGATCGGTTCTGATGTTTGGCGG
TTTTGGGGGAGTCGGGTCGCCTCCTTCATTGATTGAAGCGATATTGGACAGCGGTGTAACGGATTTGACTGTGATTTGCA
ATGACGCCGGTTTCCCGGATATCGGAATCGGCCCGCTTATTGTTAATCAACGGGTCAAAACCCTGATCGCCTCGCATATC
GGTTCCAATCCAGTAGCCGGAAAACAGATGACAGAGGGGACGTTAGAGGTTCAATTTTCACCTCAGGGAACGCTTGCGGA
ACGGATTCGCGCCGGCGGAGCGGGGCTTGGCGGTATTTTAACCGACGTGGGCATTGATAATCAAATGGTTTGCGAAAAAA
AGGACATCGTAACAGTGGCGGGAAAACGATACTTGATTGAAGAGGCGCTGACTGCTGATTTTGCTTTCATCAATGCTTAC
ATTGCAGATGAATTCGGCAATCTAACGTATGACAAAACCGCGCGCAATATGAACCCGCTTATGGCAATGGCCGCCAGGAG
AACCTTTGCCGAAGCTGAGCGTATCGTTCCGATGGGGGAGATTTCTGAAGAAATGATTGTCACACCGGGGGTTTTTGTTG
AGGGGGTTGTACGAAGCGAGGGAGTGAAGTGGAAATGGGCTTGGGAGTAG

Upstream 100 bases:

>100_bases
TCCTTTTACTATTTCAGACGGTGAAATGGAAGAGCTTATCTCTATTTTTTCAGAAACAGTTGCAGCGGTCGAAAAAAACT
TAAAAAAGGATTGACATTAA

Downstream 100 bases:

>100_bases
CAGAAAGAGAACAGATTGCAAAACGCGCTGCTACTGAAATTAAGCAGGGCATGATTGTGAATCTCGGTATCGGTATCCCT
TCCTTGGTACCGAACTTTTT

Product: aminoacyloate CoA-transferase

Products: Acetate; Butanoyl-CoA [C]

Alternate protein names: Probable CoA-transferase subunit alpha

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MAPFQKAISIDTAIADVRDGSVLMFGGFGGVGSPPSLIEAILDSGVTDLTVICNDAGFPDIGIGPLIVNQRVKTLIASHI
GSNPVAGKQMTEGTLEVQFSPQGTLAERIRAGGAGLGGILTDVGIDNQMVCEKKDIVTVAGKRYLIEEALTADFAFINAY
IADEFGNLTYDKTARNMNPLMAMAARRTFAEAERIVPMGEISEEMIVTPGVFVEGVVRSEGVKWKWAWE

Sequences:

>Translated_229_residues
MAPFQKAISIDTAIADVRDGSVLMFGGFGGVGSPPSLIEAILDSGVTDLTVICNDAGFPDIGIGPLIVNQRVKTLIASHI
GSNPVAGKQMTEGTLEVQFSPQGTLAERIRAGGAGLGGILTDVGIDNQMVCEKKDIVTVAGKRYLIEEALTADFAFINAY
IADEFGNLTYDKTARNMNPLMAMAARRTFAEAERIVPMGEISEEMIVTPGVFVEGVVRSEGVKWKWAWE
>Mature_228_residues
APFQKAISIDTAIADVRDGSVLMFGGFGGVGSPPSLIEAILDSGVTDLTVICNDAGFPDIGIGPLIVNQRVKTLIASHIG
SNPVAGKQMTEGTLEVQFSPQGTLAERIRAGGAGLGGILTDVGIDNQMVCEKKDIVTVAGKRYLIEEALTADFAFINAYI
ADEFGNLTYDKTARNMNPLMAMAARRTFAEAERIVPMGEISEEMIVTPGVFVEGVVRSEGVKWKWAWE

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family

Homologues:

Organism=Homo sapiens, GI4557817, Length=225, Percent_Identity=36.4444444444444, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI11545841, Length=224, Percent_Identity=34.8214285714286, Blast_Score=138, Evalue=4e-33,
Organism=Escherichia coli, GI1788551, Length=218, Percent_Identity=49.5412844036697, Blast_Score=211, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17531517, Length=234, Percent_Identity=34.6153846153846, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24655794, Length=223, Percent_Identity=40.3587443946188, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21358325, Length=223, Percent_Identity=40.3587443946188, Blast_Score=169, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YODS_BACSU (O34317)

Other databases:

- EMBL:   AF015775
- EMBL:   AF006665
- EMBL:   AL009126
- PIR:   E69904
- RefSeq:   NP_389854.1
- HSSP:   P76458
- ProteinModelPortal:   O34317
- SMR:   O34317
- EnsemblBacteria:   EBBACT00000002385
- GeneID:   940052
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU19730
- NMPDR:   fig|224308.1.peg.1977
- GenoList:   BSU19730
- GeneTree:   EBGT00050000001288
- HOGENOM:   HBG288750
- OMA:   YLLELPI
- ProtClustDB:   CLSK873267
- BioCyc:   BSUB:BSU19730-MONOMER
- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163
- PANTHER:   PTHR13707
- SMART:   SM00882
- TIGRFAMs:   TIGR02429

Pfam domain/function: PF01144 CoA_trans

EC number: 2.8.3.8 [C]

Molecular weight: Translated: 24411; Mature: 24280

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS01273 COA_TRANSF_1; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPFQKAISIDTAIADVRDGSVLMFGGFGGVGSPPSLIEAILDSGVTDLTVICNDAGFPD
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCC
IGIGPLIVNQRVKTLIASHIGSNPVAGKQMTEGTLEVQFSPQGTLAERIRAGGAGLGGIL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCHHHHHHHCCCCCCCHHH
TDVGIDNQMVCEKKDIVTVAGKRYLIEEALTADFAFINAYIADEFGNLTYDKTARNMNPL
HHCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHH
MAMAARRTFAEAERIVPMGEISEEMIVTPGVFVEGVVRSEGVKWKWAWE
HHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
APFQKAISIDTAIADVRDGSVLMFGGFGGVGSPPSLIEAILDSGVTDLTVICNDAGFPD
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCC
IGIGPLIVNQRVKTLIASHIGSNPVAGKQMTEGTLEVQFSPQGTLAERIRAGGAGLGGIL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCHHHHHHHCCCCCCCHHH
TDVGIDNQMVCEKKDIVTVAGKRYLIEEALTADFAFINAYIADEFGNLTYDKTARNMNPL
HHCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHH
MAMAARRTFAEAERIVPMGEISEEMIVTPGVFVEGVVRSEGVKWKWAWE
HHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Butyrate [C]

Specific reaction: Acetyl-CoA + Butyrate (n-C4:0) --> Acetate + Butanoyl-CoA [C]

General reaction: Coenzyme A transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377