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The map label for this gene is yodQ

Identifier: 16079029

GI number: 16079029

Start: 2141703

End: 2143013

Strand: Reverse

Name: yodQ

Synonym: BSU19710

Alternate gene names: 16079029

Gene position: 2143013-2141703 (Counterclockwise)

Preceding gene: 16079030

Following gene: 16079028

Centisome position: 50.84

GC content: 47.29

Gene sequence:

>1311_bases
ATGAGGATGCAAGACATTGAAAGAAAAGTAATCGAGTGGCTTGATCAGCATTCGGCCAAAGCCATTCGTCTTCTCAAAAG
GCTGATTGGGGAAAAAAGCACATTGGGGTCAGAGTTTAACGCCCAAGCTGTTGTGCTTGAAAAGCTGCGGCAATTTCATA
TGGACATTGATGTATGGGAGCCAAGCATAAAGCAATTAAAACAGCATCCCTACTTTAAATCTAACCGATCCGATTTTCAT
GAGAGCCCGAATATCGTGGCTAAAAAAACGGGAGCCGGCGGAGGCAGGTCCCTGATTTTGAACGGCCATATCGATGTTGT
GCCTGAAGGAAGCGTAAAGGATTGGAAGTATGAACCGTATCAAGCTGTCGAAGAAAACGGTAAAATATACGGCCGCGGCT
CAACGGATATGAAGGGAGGCAATACAGCCCTTCTTTTTGCTTTAGAAGCCCTGCACGCCTGCGATGTCAAACTGAAGGGA
GATGTATTGTTTCAGAGTGTTGTAGATGAAGAGTGCGGCGGCGCCGGTACACTTTCCGCCATCATGAGAGGCTATCGTGC
TGACGGGGCGCTGATTCCTGAACCGACGAATATGAAACTATTTATTAAGCAGCAGGGTTCGATGTGGTTTCGGATCACTG
TGAAGGGATTATCCGCACATGGGGGCACACGCTATGAAGGGGTAAGCGCGATTGAAAAAAGCATGCACGTTATCACAGCG
ATACAAGAGCTGGAGAAAGTCCGCAATGCGAGAATTTCAGATCCGCTGTATGACAATATCCCAATACCGGTACCGGTGAA
TATCGGCACCATCTCAGGCGGTGCCTGGCCATCTTCAGTTGCAGACCGTGTCGTCATAGAAGGGAGATGCGGAATTGCTC
CCCATGAGAAACCAGAAGCTGTAAAACTTGAATTGGAAAACTGGCTGAAGGATTTAGAATACCATGACGAATGGTTTAAA
CGCCATCCCGTACAAGTCGAATGGTTTGGCGCTCAATGGCTGCCGAATGATTTACCTGATGATCACCCTTTAATTTCTGT
GCTGCAATCAGCCTATCAAAAAATGAAACAGACAGAGCCGATTATTGAGGCTTCCCCGTGGGGAACGGATGGAGGGCTTT
TGTACCATGCAGGAGATACACCAGTGATCGTTTTCGGGCCGGGGGAAACAAAAACGGCTCATCAGGCCAATGAATACATT
GAGGTTGAAGCCATGATAGAATCTGCTAAAATTATTGCACTTTTTGTCATGGATTGGTGCGGCCTTCATACAGATGGGGA
GGATGCGGATGCTCAAGTCAATAAAGAGTAG

Upstream 100 bases:

>100_bases
TCATTTTAAAAGAGCTGATGAATGGCTCGACAATCGATGAGGTGACGAGGCTGACAGAAGCTGAAATCAAAATAGATATG
CCTTTTTCTTAAGAGGGGGA

Downstream 100 bases:

>100_bases
CGGTGTCACAGCAGTTTTGGACCATGACGGCTTTAATAAACGAATCAGAGTGGTTCGTTATGACGGAGCCATTGAGAAGG
CCCTGCCGGATATCGTGGCA

Product: acetylornithine deacetylase

Products: acetate; L-ornithine

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MRMQDIERKVIEWLDQHSAKAIRLLKRLIGEKSTLGSEFNAQAVVLEKLRQFHMDIDVWEPSIKQLKQHPYFKSNRSDFH
ESPNIVAKKTGAGGGRSLILNGHIDVVPEGSVKDWKYEPYQAVEENGKIYGRGSTDMKGGNTALLFALEALHACDVKLKG
DVLFQSVVDEECGGAGTLSAIMRGYRADGALIPEPTNMKLFIKQQGSMWFRITVKGLSAHGGTRYEGVSAIEKSMHVITA
IQELEKVRNARISDPLYDNIPIPVPVNIGTISGGAWPSSVADRVVIEGRCGIAPHEKPEAVKLELENWLKDLEYHDEWFK
RHPVQVEWFGAQWLPNDLPDDHPLISVLQSAYQKMKQTEPIIEASPWGTDGGLLYHAGDTPVIVFGPGETKTAHQANEYI
EVEAMIESAKIIALFVMDWCGLHTDGEDADAQVNKE

Sequences:

>Translated_436_residues
MRMQDIERKVIEWLDQHSAKAIRLLKRLIGEKSTLGSEFNAQAVVLEKLRQFHMDIDVWEPSIKQLKQHPYFKSNRSDFH
ESPNIVAKKTGAGGGRSLILNGHIDVVPEGSVKDWKYEPYQAVEENGKIYGRGSTDMKGGNTALLFALEALHACDVKLKG
DVLFQSVVDEECGGAGTLSAIMRGYRADGALIPEPTNMKLFIKQQGSMWFRITVKGLSAHGGTRYEGVSAIEKSMHVITA
IQELEKVRNARISDPLYDNIPIPVPVNIGTISGGAWPSSVADRVVIEGRCGIAPHEKPEAVKLELENWLKDLEYHDEWFK
RHPVQVEWFGAQWLPNDLPDDHPLISVLQSAYQKMKQTEPIIEASPWGTDGGLLYHAGDTPVIVFGPGETKTAHQANEYI
EVEAMIESAKIIALFVMDWCGLHTDGEDADAQVNKE
>Mature_436_residues
MRMQDIERKVIEWLDQHSAKAIRLLKRLIGEKSTLGSEFNAQAVVLEKLRQFHMDIDVWEPSIKQLKQHPYFKSNRSDFH
ESPNIVAKKTGAGGGRSLILNGHIDVVPEGSVKDWKYEPYQAVEENGKIYGRGSTDMKGGNTALLFALEALHACDVKLKG
DVLFQSVVDEECGGAGTLSAIMRGYRADGALIPEPTNMKLFIKQQGSMWFRITVKGLSAHGGTRYEGVSAIEKSMHVITA
IQELEKVRNARISDPLYDNIPIPVPVNIGTISGGAWPSSVADRVVIEGRCGIAPHEKPEAVKLELENWLKDLEYHDEWFK
RHPVQVEWFGAQWLPNDLPDDHPLISVLQSAYQKMKQTEPIIEASPWGTDGGLLYHAGDTPVIVFGPGETKTAHQANEYI
EVEAMIESAKIIALFVMDWCGLHTDGEDADAQVNKE

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family

Homologues:

Organism=Homo sapiens, GI4501901, Length=309, Percent_Identity=26.2135922330097, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1790395, Length=335, Percent_Identity=28.0597014925373, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789236, Length=345, Percent_Identity=24.9275362318841, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788816, Length=213, Percent_Identity=28.6384976525822, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551016, Length=186, Percent_Identity=30.6451612903226, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24649210, Length=328, Percent_Identity=23.780487804878, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356353, Length=334, Percent_Identity=22.4550898203593, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24649208, Length=194, Percent_Identity=27.319587628866, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649206, Length=227, Percent_Identity=24.2290748898678, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649202, Length=254, Percent_Identity=25.1968503937008, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24649204, Length=254, Percent_Identity=25.1968503937008, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24649212, Length=334, Percent_Identity=23.6526946107784, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YODQ_BACSU (O34984)

Other databases:

- EMBL:   AF006665
- EMBL:   AF015775
- EMBL:   AL009126
- PIR:   H69588
- RefSeq:   NP_389852.1
- ProteinModelPortal:   O34984
- SMR:   O34984
- EnsemblBacteria:   EBBACT00000002196
- GeneID:   940044
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU19710
- NMPDR:   fig|224308.1.peg.1975
- GenoList:   BSU19710
- GeneTree:   EBGT00050000000945
- HOGENOM:   HBG498131
- OMA:   PGHEVER
- PhylomeDB:   O34984
- ProtClustDB:   PRK06915
- BioCyc:   BSUB:BSU19710-MONOMER
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650
- TIGRFAMs:   TIGR01910

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: 3.5.1.16

Molecular weight: Translated: 48556; Mature: 48556

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 105-105 ACT_SITE 170-170

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMQDIERKVIEWLDQHSAKAIRLLKRLIGEKSTLGSEFNAQAVVLEKLRQFHMDIDVWE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCC
PSIKQLKQHPYFKSNRSDFHESPNIVAKKTGAGGGRSLILNGHIDVVPEGSVKDWKYEPY
HHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCEEEEECCCCCCCCCCCH
QAVEENGKIYGRGSTDMKGGNTALLFALEALHACDVKLKGDVLFQSVVDEECGGAGTLSA
HHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCHHHHH
IMRGYRADGALIPEPTNMKLFIKQQGSMWFRITVKGLSAHGGTRYEGVSAIEKSMHVITA
HHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
IQELEKVRNARISDPLYDNIPIPVPVNIGTISGGAWPSSVADRVVIEGRCGIAPHEKPEA
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHCCEEEEECCCCCCCCCCCCC
VKLELENWLKDLEYHDEWFKRHPVQVEWFGAQWLPNDLPDDHPLISVLQSAYQKMKQTEP
EEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
IIEASPWGTDGGLLYHAGDTPVIVFGPGETKTAHQANEYIEVEAMIESAKIIALFVMDWC
CEECCCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHEEEEHHHHHHHHHHHHHHHHHH
GLHTDGEDADAQVNKE
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRMQDIERKVIEWLDQHSAKAIRLLKRLIGEKSTLGSEFNAQAVVLEKLRQFHMDIDVWE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCC
PSIKQLKQHPYFKSNRSDFHESPNIVAKKTGAGGGRSLILNGHIDVVPEGSVKDWKYEPY
HHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCEEEEECCCCCCCCCCCH
QAVEENGKIYGRGSTDMKGGNTALLFALEALHACDVKLKGDVLFQSVVDEECGGAGTLSA
HHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCHHHHH
IMRGYRADGALIPEPTNMKLFIKQQGSMWFRITVKGLSAHGGTRYEGVSAIEKSMHVITA
HHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
IQELEKVRNARISDPLYDNIPIPVPVNIGTISGGAWPSSVADRVVIEGRCGIAPHEKPEA
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHCCEEEEECCCCCCCCCCCCC
VKLELENWLKDLEYHDEWFKRHPVQVEWFGAQWLPNDLPDDHPLISVLQSAYQKMKQTEP
EEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
IIEASPWGTDGGLLYHAGDTPVIVFGPGETKTAHQANEYIEVEAMIESAKIIALFVMDWC
CEECCCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHEEEEHHHHHHHHHHHHHHHHHH
GLHTDGEDADAQVNKE
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377