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The map label for this gene is des

Identifier: 16078978

GI number: 16078978

Start: 2089396

End: 2090454

Strand: Direct

Name: des

Synonym: BSU19180

Alternate gene names: 16078978

Gene position: 2089396-2090454 (Clockwise)

Preceding gene: 16078977

Following gene: 16078979

Centisome position: 49.56

GC content: 41.93

Gene sequence:

>1059_bases
ATGACTGAACAAACCATTGCACATAAACAAAAACAGCTGACAAAGCAAGTCGCTGCATTTGCTCAGCCTGAAACAAAAAA
CAGCCTGATTCAGCTTTTAAACACGTTTATCCCATTCTTCGGCCTATGGTTTCTTGCTTATCTCAGCCTCGATGTCTCCT
ATCTTCTTACGTTAGCATTAACGGTGATTGCCGCAGGTTTTCTGACAAGAATTTTTATCATCTTCCATGACTGCTGCCAT
CAATCTTTTTTCAAACAAAAACGCTATAACCACATTCTCGGTTTTCTGACAGGTGTCCTGACTTTATTCCCGTATCTTCA
ATGGCAGCACAGCCATTCGATTCATCATGCAACTAGCAGCAATCTGGATAAACGCGGAACAGGAGACATCTGGATGTTAA
CAGTAAACGAATATAAAGCTGCATCCAGACGAACAAAGCTTGCATACAGACTTTATAGAAACCCGTTTATCATGTTTATT
CTCGGACCGATTTATGTTTTTCTGATCACGAACCGTTTTAACAAAAAAGGCGCAAGACGCAAGGAACGTGTAAACACATA
CCTTACGAATCTGGCAATTGTCGCGTTGGCTGCCGCTTGCTGTCTGATCTTTGGCTGGCAATCGTTTTTACTGGTGCAAG
GCCCGATATTTCTGATTTCAGGTTCAATCGGTGTTTGGCTGTTTTATGTGCAGCATACCTTTGAAGATTCTTATTTTGAA
GCGGATGAAAACTGGAGCTACGTTCAGGCTGCTGTTGAAGGCAGCTCATTTTATAAACTCCCGAAACTGCTTCAATGGCT
AACAGGCAATATTGGTTACCACCACGTTCATCATTTGAGTCCAAAGGTGCCTAACTATAAGCTTGAAGTTGCTCATGAAC
ATCACGAACCATTAAAAAACGTACCGACAATCACCTTAAAAACAAGCCTGCAATCACTTGCGTTCCGTCTATGGGATGAA
GATAACAAACAGTTTGTGTCATTTCGGGCTATAAAACATATACCTGTAAGCCTTCCGCCTGATTCACCAGAAAAACAGAA
GCTGCGGAAGAATGCCTGA

Upstream 100 bases:

>100_bases
CATGACAAATGTCATATAGGAGGCATGATGTGTGCTACTACAAAAGACTTCTCTCATTAGCGTATACTGAACCGAGACAC
ACAATGAGAGGATACTTACT

Downstream 100 bases:

>100_bases
TGATAAAGGAGGTCTTCTAATATACTAGAAGGCTTCCTTTTTATTGTTGGAGGGTGCATTCTGGCTTTCACAATGATAAA
GTTACAAGTAAGATGAAAAG

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTEQTIAHKQKQLTKQVAAFAQPETKNSLIQLLNTFIPFFGLWFLAYLSLDVSYLLTLALTVIAAGFLTRIFIIFHDCCH
QSFFKQKRYNHILGFLTGVLTLFPYLQWQHSHSIHHATSSNLDKRGTGDIWMLTVNEYKAASRRTKLAYRLYRNPFIMFI
LGPIYVFLITNRFNKKGARRKERVNTYLTNLAIVALAAACCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFE
ADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLEVAHEHHEPLKNVPTITLKTSLQSLAFRLWDE
DNKQFVSFRAIKHIPVSLPPDSPEKQKLRKNA

Sequences:

>Translated_352_residues
MTEQTIAHKQKQLTKQVAAFAQPETKNSLIQLLNTFIPFFGLWFLAYLSLDVSYLLTLALTVIAAGFLTRIFIIFHDCCH
QSFFKQKRYNHILGFLTGVLTLFPYLQWQHSHSIHHATSSNLDKRGTGDIWMLTVNEYKAASRRTKLAYRLYRNPFIMFI
LGPIYVFLITNRFNKKGARRKERVNTYLTNLAIVALAAACCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFE
ADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLEVAHEHHEPLKNVPTITLKTSLQSLAFRLWDE
DNKQFVSFRAIKHIPVSLPPDSPEKQKLRKNA
>Mature_351_residues
TEQTIAHKQKQLTKQVAAFAQPETKNSLIQLLNTFIPFFGLWFLAYLSLDVSYLLTLALTVIAAGFLTRIFIIFHDCCHQ
SFFKQKRYNHILGFLTGVLTLFPYLQWQHSHSIHHATSSNLDKRGTGDIWMLTVNEYKAASRRTKLAYRLYRNPFIMFIL
GPIYVFLITNRFNKKGARRKERVNTYLTNLAIVALAAACCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFEA
DENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLEVAHEHHEPLKNVPTITLKTSLQSLAFRLWDED
NKQFVSFRAIKHIPVSLPPDSPEKQKLRKNA

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DES_BACSU (O34653)

Other databases:

- EMBL:   AF027868
- EMBL:   AF037430
- EMBL:   AL009126
- PIR:   B69901
- RefSeq:   NP_389799.1
- EnsemblBacteria:   EBBACT00000003605
- GeneID:   939668
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU19180
- NMPDR:   fig|224308.1.peg.1922
- GenoList:   BSU19180
- GeneTree:   EBGT00050000002471
- HOGENOM:   HBG300197
- OMA:   QHQFETT
- ProtClustDB:   CLSK2484787
- BioCyc:   BSUB:BSU19180-MONOMER
- InterPro:   IPR005804

Pfam domain/function: PF00487 FA_desaturase

EC number: 1.14.99.-

Molecular weight: Translated: 40709; Mature: 40578

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf40d764)-; HASH(0xef6ffcc)-; HASH(0xf70be90)-; HASH(0xf075b30)-; HASH(0xfde338c)-; HASH(0xcc8084c)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQTIAHKQKQLTKQVAAFAQPETKNSLIQLLNTFIPFFGLWFLAYLSLDVSYLLTLAL
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVIAAGFLTRIFIIFHDCCHQSFFKQKRYNHILGFLTGVLTLFPYLQWQHSHSIHHATSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCC
NLDKRGTGDIWMLTVNEYKAASRRTKLAYRLYRNPFIMFILGPIYVFLITNRFNKKGARR
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
KERVNTYLTNLAIVALAAACCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCC
ADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLEVAHEHHEPLKN
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECHHHCCHHHC
VPTITLKTSLQSLAFRLWDEDNKQFVSFRAIKHIPVSLPPDSPEKQKLRKNA
CCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCH
>Mature Secondary Structure 
TEQTIAHKQKQLTKQVAAFAQPETKNSLIQLLNTFIPFFGLWFLAYLSLDVSYLLTLAL
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVIAAGFLTRIFIIFHDCCHQSFFKQKRYNHILGFLTGVLTLFPYLQWQHSHSIHHATSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCC
NLDKRGTGDIWMLTVNEYKAASRRTKLAYRLYRNPFIMFILGPIYVFLITNRFNKKGARR
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
KERVNTYLTNLAIVALAAACCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCC
ADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLEVAHEHHEPLKN
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECHHHCCHHHC
VPTITLKTSLQSLAFRLWDEDNKQFVSFRAIKHIPVSLPPDSPEKQKLRKNA
CCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377