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The map label for this gene is asd

Identifier: 16078738

GI number: 16078738

Start: 1745991

End: 1747031

Strand: Direct

Name: asd

Synonym: BSU16750

Alternate gene names: 16078738

Gene position: 1745991-1747031 (Clockwise)

Preceding gene: 16078737

Following gene: 255767377

Centisome position: 41.42

GC content: 44.19

Gene sequence:

>1041_bases
ATGGGAAGAGGTTTACACGTAGCTGTTGTCGGAGCGACAGGGGCTGTGGGACAACAAATGCTTAAAACACTTGAAGACAG
AAACTTTGAAATGGACACACTTACATTGCTATCTTCAAAACGCTCTGCGGGGACAAAAGTCACGTTTAAAGGCCAAGAGC
TGACTGTTCAGGAAGCTTCTCCTGAGAGCTTTGAAGGGGTAAATATTGCTTTGTTCAGCGCCGGCGGAAGCGTATCACAA
GCATTGGCACCAGAAGCTGTAAAACGCGGCGCTATTGTTATAGATAATACGAGTGCGTTCCGCATGGATGAAAATACACC
GCTTGTTGTGCCAGAAGTGAATGAGGCAGACTTGCATGAACACAACGGCATTATTGCCAATCCAAACTGCTCTACAATCC
AAATGGTTGCGGCACTTGAACCGATCCGCAAAGCATATGGCTTAAACAAGGTCATCGTATCAACTTACCAGGCAGTATCA
GGAGCGGGTAATGAAGCTGTAAAAGAGCTTTACAGCCAAACACAGGCGATTTTAAATAAAGAAGAAATAGAGCCTGAGAT
CATGCCTGTAAAAGGTGACAAAAAACACTATCAAATCGCCTTCAACGCGATTCCGCAAATCGATAAATTCCAAGATAACG
GCTATACGTTTGAGGAAATGAAAATGATAAATGAAACGAAAAAAATCATGCACATGCCTGACCTTCAAGTAGCGGCTACA
TGTGTGAGACTGCCAATCCAAACTGGGCACTCAGAGTCCGTCTACATCGAAATAGACCGTGATGACGCTACAGTTGAAGA
TATTAAAAATCTATTGAAAGAAGCTCCGGGCGTGACACTTCAGGATGATCCAAGCCAGCAGCTTTATCCGATGCCTGCTG
ATGCTGTCGGCAAAAACGATGTGTTTGTAGGCCGCATCCGCAAAGACTTGGACAGAGCAAACGGTTTTCATTTATGGGTT
GTTTCTGATAACCTATTAAAAGGCGCGGCATGGAACTCTGTTCAAATTGCAGAAAGCCTGAAAAAACTAAACCTCGTATA
A

Upstream 100 bases:

>100_bases
AAAAAATTCGGTCATCACCCGCATATTCTATGGTAAAATAAAACGTAAAATCATAGTCAAATCAATTCAATGAAGCTGAT
TGGCGGAAGGAGTTTTACAG

Downstream 100 bases:

>100_bases
AAGAGAGAATTTTCTAAAGACGAATAGAAGAGAGTAAGGCGCTATCAGCCTGCTCTCTTCTGTTACGTCCGAATAATTTG
GAGTGAAAACAGTGAAGATA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MGRGLHVAVVGATGAVGQQMLKTLEDRNFEMDTLTLLSSKRSAGTKVTFKGQELTVQEASPESFEGVNIALFSAGGSVSQ
ALAPEAVKRGAIVIDNTSAFRMDENTPLVVPEVNEADLHEHNGIIANPNCSTIQMVAALEPIRKAYGLNKVIVSTYQAVS
GAGNEAVKELYSQTQAILNKEEIEPEIMPVKGDKKHYQIAFNAIPQIDKFQDNGYTFEEMKMINETKKIMHMPDLQVAAT
CVRLPIQTGHSESVYIEIDRDDATVEDIKNLLKEAPGVTLQDDPSQQLYPMPADAVGKNDVFVGRIRKDLDRANGFHLWV
VSDNLLKGAAWNSVQIAESLKKLNLV

Sequences:

>Translated_346_residues
MGRGLHVAVVGATGAVGQQMLKTLEDRNFEMDTLTLLSSKRSAGTKVTFKGQELTVQEASPESFEGVNIALFSAGGSVSQ
ALAPEAVKRGAIVIDNTSAFRMDENTPLVVPEVNEADLHEHNGIIANPNCSTIQMVAALEPIRKAYGLNKVIVSTYQAVS
GAGNEAVKELYSQTQAILNKEEIEPEIMPVKGDKKHYQIAFNAIPQIDKFQDNGYTFEEMKMINETKKIMHMPDLQVAAT
CVRLPIQTGHSESVYIEIDRDDATVEDIKNLLKEAPGVTLQDDPSQQLYPMPADAVGKNDVFVGRIRKDLDRANGFHLWV
VSDNLLKGAAWNSVQIAESLKKLNLV
>Mature_345_residues
GRGLHVAVVGATGAVGQQMLKTLEDRNFEMDTLTLLSSKRSAGTKVTFKGQELTVQEASPESFEGVNIALFSAGGSVSQA
LAPEAVKRGAIVIDNTSAFRMDENTPLVVPEVNEADLHEHNGIIANPNCSTIQMVAALEPIRKAYGLNKVIVSTYQAVSG
AGNEAVKELYSQTQAILNKEEIEPEIMPVKGDKKHYQIAFNAIPQIDKFQDNGYTFEEMKMINETKKIMHMPDLQVAATC
VRLPIQTGHSESVYIEIDRDDATVEDIKNLLKEAPGVTLQDDPSQQLYPMPADAVGKNDVFVGRIRKDLDRANGFHLWVV
SDNLLKGAAWNSVQIAESLKKLNLV

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1788658, Length=345, Percent_Identity=32.7536231884058, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1789841, Length=356, Percent_Identity=27.247191011236, Blast_Score=94, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=398, Percent_Identity=28.894472361809, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHAS_BACSU (Q04797)

Other databases:

- EMBL:   L08471
- EMBL:   AL009126
- EMBL:   Z22554
- PIR:   F69590
- RefSeq:   NP_389557.1
- ProteinModelPortal:   Q04797
- SMR:   Q04797
- PhosSite:   Q04797
- EnsemblBacteria:   EBBACT00000000448
- GeneID:   939654
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU16750
- NMPDR:   fig|224308.1.peg.1678
- GenoList:   BSU16750
- GeneTree:   EBGT00050000002435
- HOGENOM:   HBG518238
- OMA:   LELWLCG
- PhylomeDB:   Q04797
- ProtClustDB:   PRK14874
- BioCyc:   BSUB:BSU16750-MONOMER
- BioCyc:   MetaCyc:MONOMER-6564
- BRENDA:   1.2.1.11
- GO:   GO:0005737
- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF000148
- SMART:   SM00859
- TIGRFAMs:   TIGR01296

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.11

Molecular weight: Translated: 37848; Mature: 37716

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS01103 ASD

Important sites: ACT_SITE 130-130

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRGLHVAVVGATGAVGQQMLKTLEDRNFEMDTLTLLSSKRSAGTKVTFKGQELTVQEAS
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCEEEEECCC
PESFEGVNIALFSAGGSVSQALAPEAVKRGAIVIDNTSAFRMDENTPLVVPEVNEADLHE
CCCCCCEEEEEEECCCCHHHHHCHHHHHCCEEEEECCCEEEECCCCCEEEECCCCCCHHH
HNGIIANPNCSTIQMVAALEPIRKAYGLNKVIVSTYQAVSGAGNEAVKELYSQTQAILNK
CCCEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EEIEPEIMPVKGDKKHYQIAFNAIPQIDKFQDNGYTFEEMKMINETKKIMHMPDLQVAAT
HHCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
CVRLPIQTGHSESVYIEIDRDDATVEDIKNLLKEAPGVTLQDDPSQQLYPMPADAVGKND
HHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHCCCCC
VFVGRIRKDLDRANGFHLWVVSDNLLKGAAWNSVQIAESLKKLNLV
EEHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRGLHVAVVGATGAVGQQMLKTLEDRNFEMDTLTLLSSKRSAGTKVTFKGQELTVQEAS
CCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCEEEEECCC
PESFEGVNIALFSAGGSVSQALAPEAVKRGAIVIDNTSAFRMDENTPLVVPEVNEADLHE
CCCCCCEEEEEEECCCCHHHHHCHHHHHCCEEEEECCCEEEECCCCCEEEECCCCCCHHH
HNGIIANPNCSTIQMVAALEPIRKAYGLNKVIVSTYQAVSGAGNEAVKELYSQTQAILNK
CCCEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EEIEPEIMPVKGDKKHYQIAFNAIPQIDKFQDNGYTFEEMKMINETKKIMHMPDLQVAAT
HHCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
CVRLPIQTGHSESVYIEIDRDDATVEDIKNLLKEAPGVTLQDDPSQQLYPMPADAVGKND
HHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHCCCCC
VFVGRIRKDLDRANGFHLWVVSDNLLKGAAWNSVQIAESLKKLNLV
EEHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520