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The map label for this gene is hslU

Identifier: 16078679

GI number: 16078679

Start: 1688676

End: 1690079

Strand: Direct

Name: hslU

Synonym: BSU16160

Alternate gene names: 16078679

Gene position: 1688676-1690079 (Clockwise)

Preceding gene: 16078678

Following gene: 16078680

Centisome position: 40.06

GC content: 42.74

Gene sequence:

>1404_bases
ATGGAAAAAAAACCGTTAACTCCTAGACAGATTGTAGATCGGTTAGACCAATATATTGTCGGTCAGCAAAATGCGAAAAA
AGCTGTCGCCGTGGCATTAAGAAACCGCTATAGAAGAAGTCTTCTGGATGAAAAGCTGAAGGACGAGGTCGTTCCGAAAA
ACATTTTAATGATGGGTCCTACCGGCGTCGGGAAAACTGAAATTGCCAGACGAATCGCTAAGCTTTCAGGTGCGCCATTT
ATCAAAATTGAAGCTACTAAATTTACCGAAGTCGGCTATGTAGGCAGAGATGTTGAATCAATGGTCAGAGATCTTGTGGA
GACTTCTGTTCGGCTTATAAAAGAAGAGAAAATGAATGAAGTAAAGGAACAGGCAGAAGAAAATGCAAACAAACGCATTG
TTCGTCTGTTAGTTCCTGGGAAGAAAAAACAATCTGGTGTTAAAAATCCGTTTGAAATGTTTTTTGGAGGCAGCCAGCCG
AATGGTGAAGATGAGGCGGAGAGCCAGGAAGAAGCAAACATCGAAGAAAAAAGAAAACGAATGGCGCATCAGCTGGCTTT
AGGAGAGCTCGAAGACTACTATGTAACAGTAGAAGTCGAAGAACAGCAGCCTTCTATGTTTGACATGCTGCAGGGCTCGG
GTATGGAGCAGATGGGTATGAACATGCAGGATGCGCTGAGCGGATTAATGCCAAAGAAAAAGAAGCGGCGCAAAATGACA
GTCAGAGAAGCCAGAAAAGTCCTGACGAATGAAGAAGCAAGCAAACTCATCGATATGGATGAAGTCGGCCAGGAAGCTGT
TCAGAGAGCAGAAGAGAGCGGGATTATCTTTATCGATGAGATTGATAAAATCGCAAAGAACGGCGGTGCATCTTCTTCTG
CCGATGTTTCAAGAGAAGGTGTTCAGCGGGATATCCTTCCGATTGTTGAAGGTTCTACCGTTGTCACAAAATATGGTTCT
GTAAAAACAGACCATGTATTATTTATTGCAGCAGGAGCGTTTCATATGGCCAAACCGTCTGATTTGATTCCTGAGCTGCA
GGGGCGTTTCCCGATTCGTGTAGAACTGAACAAACTCACGGTAGACGACTTCGTGAGAATTTTGGTTGAGCCGGATAATG
CGCTGCTGAAACAATATCAGGCATTATTGCAGACAGAAGGTATATCTCTTGAATTTTCTGACGAAGCTATTCATAAGATT
GCTGAAGTTGCTTATCATGTGAACCAGGACACAGATAATATCGGTGCGAGACGCCTTCATACAATACTTGAACGCCTATT
AGAAGATTTGTCGTTTGAAGCTCCAGATGTAACGATGGAGAAAATAACGATTACACCACAGTATGTCGAAGAAAAGCTCG
GAACGATAGCCAAAAACAAAGATTTAAGTCAATTTATATTGTGA

Upstream 100 bases:

>100_bases
GAGATTGCCAGAGCCGCGTTAGAAACAGCAGGCGAAATTTGTGTTTACACGAACGATCAAATCATACTGGAAGAGCTTGA
ATAGAAAGGACTTGAGGCGC

Downstream 100 bases:

>100_bases
AAAATTTAATATGAGGAATGTTTAGGAGGATTATTTATCATGGCTTTATTACAAAAAACAAGAATTATTAACTCCATGCT
GCAAGCTGCGGCAGGGAAAC

Product: ATP-dependent protease ATP-binding subunit HslU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MEKKPLTPRQIVDRLDQYIVGQQNAKKAVAVALRNRYRRSLLDEKLKDEVVPKNILMMGPTGVGKTEIARRIAKLSGAPF
IKIEATKFTEVGYVGRDVESMVRDLVETSVRLIKEEKMNEVKEQAEENANKRIVRLLVPGKKKQSGVKNPFEMFFGGSQP
NGEDEAESQEEANIEEKRKRMAHQLALGELEDYYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSGLMPKKKKRRKMT
VREARKVLTNEEASKLIDMDEVGQEAVQRAEESGIIFIDEIDKIAKNGGASSSADVSREGVQRDILPIVEGSTVVTKYGS
VKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELNKLTVDDFVRILVEPDNALLKQYQALLQTEGISLEFSDEAIHKI
AEVAYHVNQDTDNIGARRLHTILERLLEDLSFEAPDVTMEKITITPQYVEEKLGTIAKNKDLSQFIL

Sequences:

>Translated_467_residues
MEKKPLTPRQIVDRLDQYIVGQQNAKKAVAVALRNRYRRSLLDEKLKDEVVPKNILMMGPTGVGKTEIARRIAKLSGAPF
IKIEATKFTEVGYVGRDVESMVRDLVETSVRLIKEEKMNEVKEQAEENANKRIVRLLVPGKKKQSGVKNPFEMFFGGSQP
NGEDEAESQEEANIEEKRKRMAHQLALGELEDYYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSGLMPKKKKRRKMT
VREARKVLTNEEASKLIDMDEVGQEAVQRAEESGIIFIDEIDKIAKNGGASSSADVSREGVQRDILPIVEGSTVVTKYGS
VKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELNKLTVDDFVRILVEPDNALLKQYQALLQTEGISLEFSDEAIHKI
AEVAYHVNQDTDNIGARRLHTILERLLEDLSFEAPDVTMEKITITPQYVEEKLGTIAKNKDLSQFIL
>Mature_467_residues
MEKKPLTPRQIVDRLDQYIVGQQNAKKAVAVALRNRYRRSLLDEKLKDEVVPKNILMMGPTGVGKTEIARRIAKLSGAPF
IKIEATKFTEVGYVGRDVESMVRDLVETSVRLIKEEKMNEVKEQAEENANKRIVRLLVPGKKKQSGVKNPFEMFFGGSQP
NGEDEAESQEEANIEEKRKRMAHQLALGELEDYYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSGLMPKKKKRRKMT
VREARKVLTNEEASKLIDMDEVGQEAVQRAEESGIIFIDEIDKIAKNGGASSSADVSREGVQRDILPIVEGSTVVTKYGS
VKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELNKLTVDDFVRILVEPDNALLKQYQALLQTEGISLEFSDEAIHKI
AEVAYHVNQDTDNIGARRLHTILERLLEDLSFEAPDVTMEKITITPQYVEEKLGTIAKNKDLSQFIL

Specific function: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity [H]

COG id: COG1220

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family. HslU subfamily [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=111, Percent_Identity=36.036036036036, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1790366, Length=462, Percent_Identity=50.6493506493506, Blast_Score=470, Evalue=1e-134,
Organism=Escherichia coli, GI1786642, Length=232, Percent_Identity=34.4827586206897, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71982905, Length=256, Percent_Identity=30.078125, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=256, Percent_Identity=30.078125, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6319704, Length=117, Percent_Identity=36.7521367521368, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648291, Length=249, Percent_Identity=31.7269076305221, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24648289, Length=249, Percent_Identity=31.7269076305221, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR019489
- InterPro:   IPR004491 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 52587; Mature: 52587

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKPLTPRQIVDRLDQYIVGQQNAKKAVAVALRNRYRRSLLDEKLKDEVVPKNILMMGP
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
TGVGKTEIARRIAKLSGAPFIKIEATKFTEVGYVGRDVESMVRDLVETSVRLIKEEKMNE
CCCCHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKEQAEENANKRIVRLLVPGKKKQSGVKNPFEMFFGGSQPNGEDEAESQEEANIEEKRKR
HHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHH
MAHQLALGELEDYYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSGLMPKKKKRRKMT
HHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCHHHHCCCHHHHHHHCCCCHHHHHHHH
VREARKVLTNEEASKLIDMDEVGQEAVQRAEESGIIFIDEIDKIAKNGGASSSADVSREG
HHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCHHHHHH
VQRDILPIVEGSTVVTKYGSVKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELNKLT
HHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCHHCCCCHHHHHHHCCCCCEEEEECCCC
VDDFVRILVEPDNALLKQYQALLQTEGISLEFSDEAIHKIAEVAYHVNQDTDNIGARRLH
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHH
TILERLLEDLSFEAPDVTMEKITITPQYVEEKLGTIAKNKDLSQFIL
HHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MEKKPLTPRQIVDRLDQYIVGQQNAKKAVAVALRNRYRRSLLDEKLKDEVVPKNILMMGP
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
TGVGKTEIARRIAKLSGAPFIKIEATKFTEVGYVGRDVESMVRDLVETSVRLIKEEKMNE
CCCCHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKEQAEENANKRIVRLLVPGKKKQSGVKNPFEMFFGGSQPNGEDEAESQEEANIEEKRKR
HHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHH
MAHQLALGELEDYYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSGLMPKKKKRRKMT
HHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCHHHHCCCHHHHHHHCCCCHHHHHHHH
VREARKVLTNEEASKLIDMDEVGQEAVQRAEESGIIFIDEIDKIAKNGGASSSADVSREG
HHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCHHHHHH
VQRDILPIVEGSTVVTKYGSVKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELNKLT
HHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCHHCCCCHHHHHHHCCCCCEEEEECCCC
VDDFVRILVEPDNALLKQYQALLQTEGISLEFSDEAIHKIAEVAYHVNQDTDNIGARRLH
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHH
TILERLLEDLSFEAPDVTMEKITITPQYVEEKLGTIAKNKDLSQFIL
HHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA