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The map label for this gene is fabD

Identifier: 16078653

GI number: 16078653

Start: 1663567

End: 1664520

Strand: Direct

Name: fabD

Synonym: BSU15900

Alternate gene names: 16078653

Gene position: 1663567-1664520 (Clockwise)

Preceding gene: 16078652

Following gene: 16078654

Centisome position: 39.46

GC content: 45.28

Gene sequence:

>954_bases
ATGAGTAAGATTGCATTTTTATTCCCGGGTCAGGGATCACAATTTATCGGCATGGGAAAAGAGCTTTATGAGCAGGTGCC
TGCTGCAAAGCGTCTGTTTGATGAAGCCGATGAAACGTTGGAAACAAAACTCAGCTCGCTTATTTTTGAGGGGGATGCTG
AAGAATTAACACTTACATACAATGCGCAGCCTGCTTTGCTTACGACAAGCATCGCTGTTCTTGAGAAATTTAAAGAATCT
GGCATTACACCTGATTTCACAGCAGGACACAGCCTTGGTGAATATTCTGCACTGGTTGCGGCTGGCGCTCTGTCTTTCAA
AGATGCTGTTTATACTGTCAGAAAGCGCGGAGAGTTTATGAATGAAGCGGTGCCGGCTGGCGAAGGAGCAATGGCTGCGA
TTCTCGGCATGGATGCTGAAGCATTAAAGCAAGTAACCGATAAAGTCACAGAGGAAGGCAACCTTGTACAGCTTGCGAAT
CTCAACTGTCCTGGCCAAATCGTCATTTCCGGAACAGCTAAAGGGGTTGAGCTTGCATCTGAACTGGCAAAAGAGAACGG
CGCAAAACGCGCAATTCCGCTTGAAGTAAGCGGTCCGTTCCATTCTGAACTGATGAAACCGGCTGCTGAAAAGCTGAAAG
AGGTATTGGACGCCTGTGACATAAAAGACGCTGACGTTCCGGTCATCTCAAATGTTTCTGCTGACGTGATGACTGAAAAA
GCAGATATCAAAGAAAAACTTATTGAGCAGCTTTACTCTCCGGTTCGTTTTGAGGAAAGCATTAACAAGCTGATCGCAGA
GGGTGTTACGACTTTTATTGAAATCGGTCCCGGAAAAGTGCTTTCAGGCCTTGTGAAAAAAGTGAATAGACGGTTAAAAA
CAATTGCTGTATCAGATCCGGAAACGATCGAGCTGGCAATTCAAACGCTTAAGGAGGAGAATGATAATGCTTAA

Upstream 100 bases:

>100_bases
TCGGCAAGCAAGAGAGATGGTCAGCCAAAATGTGGCTGCGCTCATTCAGGAAGAAGTGAAAGAAGAAAAAACAGATGAGT
AGTCTGGAGGTTTTTACATC

Downstream 100 bases:

>100_bases
TGATAAAACGGCTATTGTCACTGGCGCATCCCGCGGAATCGGCCGCTCAATCGCCCTTGATCTGGCAAAAAGCGGAGCAA
ATGTTGTCGTGAACTACTCC

Product: malonyl CoA:acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSKIAFLFPGQGSQFIGMGKELYEQVPAAKRLFDEADETLETKLSSLIFEGDAEELTLTYNAQPALLTTSIAVLEKFKES
GITPDFTAGHSLGEYSALVAAGALSFKDAVYTVRKRGEFMNEAVPAGEGAMAAILGMDAEALKQVTDKVTEEGNLVQLAN
LNCPGQIVISGTAKGVELASELAKENGAKRAIPLEVSGPFHSELMKPAAEKLKEVLDACDIKDADVPVISNVSADVMTEK
ADIKEKLIEQLYSPVRFEESINKLIAEGVTTFIEIGPGKVLSGLVKKVNRRLKTIAVSDPETIELAIQTLKEENDNA

Sequences:

>Translated_317_residues
MSKIAFLFPGQGSQFIGMGKELYEQVPAAKRLFDEADETLETKLSSLIFEGDAEELTLTYNAQPALLTTSIAVLEKFKES
GITPDFTAGHSLGEYSALVAAGALSFKDAVYTVRKRGEFMNEAVPAGEGAMAAILGMDAEALKQVTDKVTEEGNLVQLAN
LNCPGQIVISGTAKGVELASELAKENGAKRAIPLEVSGPFHSELMKPAAEKLKEVLDACDIKDADVPVISNVSADVMTEK
ADIKEKLIEQLYSPVRFEESINKLIAEGVTTFIEIGPGKVLSGLVKKVNRRLKTIAVSDPETIELAIQTLKEENDNA
>Mature_316_residues
SKIAFLFPGQGSQFIGMGKELYEQVPAAKRLFDEADETLETKLSSLIFEGDAEELTLTYNAQPALLTTSIAVLEKFKESG
ITPDFTAGHSLGEYSALVAAGALSFKDAVYTVRKRGEFMNEAVPAGEGAMAAILGMDAEALKQVTDKVTEEGNLVQLANL
NCPGQIVISGTAKGVELASELAKENGAKRAIPLEVSGPFHSELMKPAAEKLKEVLDACDIKDADVPVISNVSADVMTEKA
DIKEKLIEQLYSPVRFEESINKLIAEGVTTFIEIGPGKVLSGLVKKVNRRLKTIAVSDPETIELAIQTLKEENDNA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=33.2225913621262, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=38.5321100917431, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI41872631, Length=296, Percent_Identity=28.0405405405405, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=44.336569579288, Blast_Score=243, Evalue=8e-66,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=34.4709897610922, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=29.1525423728814, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=35.5481727574751, Blast_Score=147, Evalue=8e-36,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FABD_BACSU (P71019)

Other databases:

- EMBL:   U59433
- EMBL:   Y13937
- EMBL:   AL009126
- PIR:   H69620
- RefSeq:   NP_389472.1
- ProteinModelPortal:   P71019
- SMR:   P71019
- EnsemblBacteria:   EBBACT00000002793
- GeneID:   938488
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU15900
- NMPDR:   fig|224308.1.peg.1592
- GenoList:   BSU15900
- GeneTree:   EBGT00050000000472
- HOGENOM:   HBG687898
- OMA:   FKDAVPL
- PhylomeDB:   P71019
- ProtClustDB:   CLSK2460921
- BioCyc:   BSUB:BSU15900-MONOMER
- BRENDA:   2.3.1.39
- GO:   GO:0005488
- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036
- Gene3D:   G3DSA:3.40.366.10
- TIGRFAMs:   TIGR00128

Pfam domain/function: PF00698 Acyl_transf_1; SSF52151 Acyl_Trfase/lysoPlipase; SSF55048 Malonyl_transacylase_ACP-bd

EC number: =2.3.1.39

Molecular weight: Translated: 34035; Mature: 33904

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS00039 DEAD_ATP_HELICASE

Important sites: ACT_SITE 91-91 ACT_SITE 201-201

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIAFLFPGQGSQFIGMGKELYEQVPAAKRLFDEADETLETKLSSLIFEGDAEELTLTY
CCCEEEEECCCCCHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
NAQPALLTTSIAVLEKFKESGITPDFTAGHSLGEYSALVAAGALSFKDAVYTVRKRGEFM
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEAVPAGEGAMAAILGMDAEALKQVTDKVTEEGNLVQLANLNCPGQIVISGTAKGVELAS
HHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCHHHHHHH
ELAKENGAKRAIPLEVSGPFHSELMKPAAEKLKEVLDACDIKDADVPVISNVSADVMTEK
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHH
ADIKEKLIEQLYSPVRFEESINKLIAEGVTTFIEIGPGKVLSGLVKKVNRRLKTIAVSDP
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEECCCC
ETIELAIQTLKEENDNA
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKIAFLFPGQGSQFIGMGKELYEQVPAAKRLFDEADETLETKLSSLIFEGDAEELTLTY
CCEEEEECCCCCHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
NAQPALLTTSIAVLEKFKESGITPDFTAGHSLGEYSALVAAGALSFKDAVYTVRKRGEFM
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEAVPAGEGAMAAILGMDAEALKQVTDKVTEEGNLVQLANLNCPGQIVISGTAKGVELAS
HHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCHHHHHHH
ELAKENGAKRAIPLEVSGPFHSELMKPAAEKLKEVLDACDIKDADVPVISNVSADVMTEK
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHH
ADIKEKLIEQLYSPVRFEESINKLIAEGVTTFIEIGPGKVLSGLVKKVNRRLKTIAVSDP
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEECCCC
ETIELAIQTLKEENDNA
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377