Definition Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome.
Accession NC_000964
Length 4,215,606

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The map label for this gene is ylaM

Identifier: 16078547

GI number: 16078547

Start: 1551385

End: 1552314

Strand: Direct

Name: ylaM

Synonym: BSU14830

Alternate gene names: 16078547

Gene position: 1551385-1552314 (Clockwise)

Preceding gene: 16078545

Following gene: 16078548

Centisome position: 36.8

GC content: 43.33

Gene sequence:

>930_bases
ATGGTATGCCAGCATAATGATGAGCTTGAAGCCTTAGTGAAAAAGGCGAAAAAAGTAACGGACAAGGGGGAGGTAGCCAG
CTATATTCCCGCCTTGGCAAAAGCTGATAAACACGACCTGTCAGTGGCGATTTATTATTCCAATAATGTTTGTCTGTCAG
CAGGTGACGTAGAAAAAACATTTACGCTTCAAAGTATATCGAAAGTCCTTTCCCTTGCTTTGGTGTTAATGGAATACGGC
AAAGATAAGGTCTTCAGTTATGTTGGACAGGAGCCGACCGGTGATCCGTTTAATTCAATTATCAAGCTCGAAACAGTGAA
TCCGAGCAAGCCGTTAAACCCTATGATTAATGCCGGGGCATTGGTAGTGACAAGTCTGATAAGGGGAAGAACGGTAAAAG
AGAGACTTGATTATTTGCTTTCTTTTATCAGAAGGCTGACAAACAACCAAGAGATTACATACTGCCGGGAAGTGGCTGAA
TCTGAATACAGCACTTCAATGATTAATCGGGCGATGTGTTATTATATGAAGCAGTACGGCATTTTTGAAGATGATGTAGA
GGCAGTAATGGATTTATATACGAAGCAATGCGCGATTGAGATGAACAGCTTGGATTTAGCGAAAATCGGATCTGTATTCG
CATTGAACGGCAGACATCCAGAGACTGGGGAGCAGGTCATCTCAAAAGATGTCGCTAGAATTTGCAAAACGTTTATGGTG
ACGTGCGGAATGTACAATGCAAGCGGGGAATTCGCAATTAAGGTCGGAATTCCTGCGAAAAGCGGCGTATCCGGCGGGAT
AATGGGCATTTCGCCTTACGATTTCGGGATCGGCATATTCGGCCCCGCATTAGACGAAAAAGGGAACAGCATTGCAGGTG
TAAAGCTTTTGGAAATAATGTCTGAGATGTACAGGCTGAGTATTTTTTAA

Upstream 100 bases:

>100_bases
TATGACCCCCTTCTCTCAAAATTATAAAAGTTTTCGCATGAATTGTCACTTTGTGTACAAATTATGTGTATTGAAATGCT
GAGGGAACGAGGGTGTTTGC

Downstream 100 bases:

>100_bases
TTTATGTCATATGCTTAAATCCTCTTGCATTTTCTGTTGATACCCTTTATGATAAATAGAAGAATTAGGTACTCGCCTGG
GGAACGGAGGGATACTTTTG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MVCQHNDELEALVKKAKKVTDKGEVASYIPALAKADKHDLSVAIYYSNNVCLSAGDVEKTFTLQSISKVLSLALVLMEYG
KDKVFSYVGQEPTGDPFNSIIKLETVNPSKPLNPMINAGALVVTSLIRGRTVKERLDYLLSFIRRLTNNQEITYCREVAE
SEYSTSMINRAMCYYMKQYGIFEDDVEAVMDLYTKQCAIEMNSLDLAKIGSVFALNGRHPETGEQVISKDVARICKTFMV
TCGMYNASGEFAIKVGIPAKSGVSGGIMGISPYDFGIGIFGPALDEKGNSIAGVKLLEIMSEMYRLSIF

Sequences:

>Translated_309_residues
MVCQHNDELEALVKKAKKVTDKGEVASYIPALAKADKHDLSVAIYYSNNVCLSAGDVEKTFTLQSISKVLSLALVLMEYG
KDKVFSYVGQEPTGDPFNSIIKLETVNPSKPLNPMINAGALVVTSLIRGRTVKERLDYLLSFIRRLTNNQEITYCREVAE
SEYSTSMINRAMCYYMKQYGIFEDDVEAVMDLYTKQCAIEMNSLDLAKIGSVFALNGRHPETGEQVISKDVARICKTFMV
TCGMYNASGEFAIKVGIPAKSGVSGGIMGISPYDFGIGIFGPALDEKGNSIAGVKLLEIMSEMYRLSIF
>Mature_309_residues
MVCQHNDELEALVKKAKKVTDKGEVASYIPALAKADKHDLSVAIYYSNNVCLSAGDVEKTFTLQSISKVLSLALVLMEYG
KDKVFSYVGQEPTGDPFNSIIKLETVNPSKPLNPMINAGALVVTSLIRGRTVKERLDYLLSFIRRLTNNQEITYCREVAE
SEYSTSMINRAMCYYMKQYGIFEDDVEAVMDLYTKQCAIEMNSLDLAKIGSVFALNGRHPETGEQVISKDVARICKTFMV
TCGMYNASGEFAIKVGIPAKSGVSGGIMGISPYDFGIGIFGPALDEKGNSIAGVKLLEIMSEMYRLSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=295, Percent_Identity=37.2881355932203, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI20336214, Length=287, Percent_Identity=35.191637630662, Blast_Score=171, Evalue=7e-43,
Organism=Escherichia coli, GI1787804, Length=308, Percent_Identity=38.961038961039, Blast_Score=235, Evalue=2e-63,
Organism=Escherichia coli, GI1786693, Length=289, Percent_Identity=38.0622837370242, Blast_Score=203, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17532727, Length=292, Percent_Identity=38.6986301369863, Blast_Score=203, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17507019, Length=289, Percent_Identity=35.6401384083045, Blast_Score=193, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI193204073, Length=285, Percent_Identity=38.5964912280702, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI193204075, Length=287, Percent_Identity=38.3275261324042, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI281363241, Length=296, Percent_Identity=37.5, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653162, Length=296, Percent_Identity=37.5, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653164, Length=299, Percent_Identity=37.123745819398, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24653156, Length=299, Percent_Identity=37.123745819398, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24653158, Length=299, Percent_Identity=37.123745819398, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281363239, Length=299, Percent_Identity=37.123745819398, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI116008307, Length=299, Percent_Identity=37.123745819398, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24653166, Length=299, Percent_Identity=37.123745819398, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA2_BACSU (O07637)

Other databases:

- EMBL:   Z97025
- EMBL:   AL009126
- PIR:   C69873
- RefSeq:   NP_389366.1
- ProteinModelPortal:   O07637
- SMR:   O07637
- EnsemblBacteria:   EBBACT00000003935
- GeneID:   939852
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14830
- NMPDR:   fig|224308.1.peg.1485
- GenoList:   BSU14830
- GeneTree:   EBGT00050000001778
- HOGENOM:   HBG512335
- PhylomeDB:   O07637
- ProtClustDB:   PRK00971
- BioCyc:   BSUB:BSU14830-MONOMER
- BRENDA:   3.5.1.2
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 34013; Mature: 34013

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MVCQHNDELEALVKKAKKVTDKGEVASYIPALAKADKHDLSVAIYYSNNVCLSAGDVEKT
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCCHHH
FTLQSISKVLSLALVLMEYGKDKVFSYVGQEPTGDPFNSIIKLETVNPSKPLNPMINAGA
HHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCCCHHHCCHH
LVVTSLIRGRTVKERLDYLLSFIRRLTNNQEITYCREVAESEYSTSMINRAMCYYMKQYG
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IFEDDVEAVMDLYTKQCAIEMNSLDLAKIGSVFALNGRHPETGEQVISKDVARICKTFMV
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
TCGMYNASGEFAIKVGIPAKSGVSGGIMGISPYDFGIGIFGPALDEKGNSIAGVKLLEIM
HHCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SEMYRLSIF
HHHHHHCCC
>Mature Secondary Structure
MVCQHNDELEALVKKAKKVTDKGEVASYIPALAKADKHDLSVAIYYSNNVCLSAGDVEKT
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCCHHH
FTLQSISKVLSLALVLMEYGKDKVFSYVGQEPTGDPFNSIIKLETVNPSKPLNPMINAGA
HHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCCCHHHCCHH
LVVTSLIRGRTVKERLDYLLSFIRRLTNNQEITYCREVAESEYSTSMINRAMCYYMKQYG
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IFEDDVEAVMDLYTKQCAIEMNSLDLAKIGSVFALNGRHPETGEQVISKDVARICKTFMV
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
TCGMYNASGEFAIKVGIPAKSGVSGGIMGISPYDFGIGIFGPALDEKGNSIAGVKLLEIM
HHCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SEMYRLSIF
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377