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The map label for this gene is suhB

Identifier: 16078531

GI number: 16078531

Start: 1537441

End: 1538238

Strand: Direct

Name: suhB

Synonym: BSU14670

Alternate gene names: 16078531

Gene position: 1537441-1538238 (Clockwise)

Preceding gene: 16078530

Following gene: 16078532

Centisome position: 36.47

GC content: 42.98

Gene sequence:

>798_bases
ATGACAAATTGGACGGAAATCGATGAGATTGCAAAGAAATGGATAAGAGAAGCAGGCGCGAGAATTACACAATCCATGCA
TGAAAGCCTGACAATTGAAACGAAATCAAATCCGAATGATTTAGTCACCAATATTGACAAAGAAACCGAAAAGTTTTTCA
TTGATCGAATTCAAGAAACATTTCCGGGACATCGGATACTCGGTGAAGAGGGGCAAGGAGACAAAATCCACTCACTTGAG
GGAGTCGTATGGATTATTGATCCGATTGATGGGACGATGAATTTTGTGCACCAGCAAAGAAATTTTGCGATTTCCATTGG
GATTTTTGAAAACGGTGAAGGTAAAATCGGTTTAATTTATGATGTGGTGCACGATGAGTTGTATCACGCATTTAGCGGCA
GAGGAGCTTATATGAATGAAACGAAGCTGGCTCCATTAAAAGAAACCGTCATTGAAGAAGCGATTCTTGCCATTAATGCA
ACATGGGTAACGGAAAACAGAAGAATTGATCAAAGTGTGTTAGCGCCACTTGTGAAAAGAGTCAGAGGCACACGCTCCTA
CGGTTCTGCCGCTTTAGAGCTGGCAAATGTCGCGGCAGGAAGAATAGATGCTTACATCACGATGCGGCTTGCGCCATGGG
ACTACGCAGCCGGCTGTGTGCTGTTAAATGAAGTAGGAGGCACCTATACGACCATTGAAGGAGAGCCGTTTACCTTTTTA
GAAAACCACAGTGTGCTAGCCGGAAACCCATCTATACATAAAACGATATTTGAAGAGTATCTTCATGCTCGGAAGTAG

Upstream 100 bases:

>100_bases
TTTACGTGAGAAGGGATATTTTTCATTTTCCTTGCTTTTTCATTGCCGTTATCAGTATCCTATAAAATAAAAGGTCTACA
TAGAAGAGAGGTACGAACGA

Downstream 100 bases:

>100_bases
GCCATTTGAGCAGGATGATCTCAGCTTGTTAGAAAAGCTCGCGGAGGCTCATCCTGTATGGAAAGAGGAGGAGTTTGGAG
ATAAAGATGCAGAAGACTAT

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTNWTEIDEIAKKWIREAGARITQSMHESLTIETKSNPNDLVTNIDKETEKFFIDRIQETFPGHRILGEEGQGDKIHSLE
GVVWIIDPIDGTMNFVHQQRNFAISIGIFENGEGKIGLIYDVVHDELYHAFSGRGAYMNETKLAPLKETVIEEAILAINA
TWVTENRRIDQSVLAPLVKRVRGTRSYGSAALELANVAAGRIDAYITMRLAPWDYAAGCVLLNEVGGTYTTIEGEPFTFL
ENHSVLAGNPSIHKTIFEEYLHARK

Sequences:

>Translated_265_residues
MTNWTEIDEIAKKWIREAGARITQSMHESLTIETKSNPNDLVTNIDKETEKFFIDRIQETFPGHRILGEEGQGDKIHSLE
GVVWIIDPIDGTMNFVHQQRNFAISIGIFENGEGKIGLIYDVVHDELYHAFSGRGAYMNETKLAPLKETVIEEAILAINA
TWVTENRRIDQSVLAPLVKRVRGTRSYGSAALELANVAAGRIDAYITMRLAPWDYAAGCVLLNEVGGTYTTIEGEPFTFL
ENHSVLAGNPSIHKTIFEEYLHARK
>Mature_264_residues
TNWTEIDEIAKKWIREAGARITQSMHESLTIETKSNPNDLVTNIDKETEKFFIDRIQETFPGHRILGEEGQGDKIHSLEG
VVWIIDPIDGTMNFVHQQRNFAISIGIFENGEGKIGLIYDVVHDELYHAFSGRGAYMNETKLAPLKETVIEEAILAINAT
WVTENRRIDQSVLAPLVKRVRGTRSYGSAALELANVAAGRIDAYITMRLAPWDYAAGCVLLNEVGGTYTTIEGEPFTFLE
NHSVLAGNPSIHKTIFEEYLHARK

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

Organism=Homo sapiens, GI221625487, Length=261, Percent_Identity=33.7164750957854, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI5031789, Length=261, Percent_Identity=33.7164750957854, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI7657236, Length=251, Percent_Identity=33.4661354581673, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI221625507, Length=164, Percent_Identity=37.1951219512195, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1788882, Length=250, Percent_Identity=33.6, Blast_Score=145, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI193202572, Length=259, Percent_Identity=32.046332046332, Blast_Score=143, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI193202570, Length=266, Percent_Identity=31.9548872180451, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6320493, Length=209, Percent_Identity=30.622009569378, Blast_Score=105, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6321836, Length=210, Percent_Identity=30.4761904761905, Blast_Score=99, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24664922, Length=262, Percent_Identity=33.969465648855, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24664926, Length=256, Percent_Identity=33.59375, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357329, Length=257, Percent_Identity=30.7392996108949, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI21357303, Length=245, Percent_Identity=32.2448979591837, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357957, Length=240, Percent_Identity=30.8333333333333, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24664918, Length=225, Percent_Identity=28.8888888888889, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUHB_BACSU (Q45499)

Other databases:

- EMBL:   AF012285
- EMBL:   AL009126
- PIR:   E69864
- RefSeq:   NP_389350.1
- ProteinModelPortal:   Q45499
- SMR:   Q45499
- EnsemblBacteria:   EBBACT00000000817
- GeneID:   935986
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14670
- NMPDR:   fig|224308.1.peg.1469
- GenoList:   BSU14670
- GeneTree:   EBGT00050000002534
- HOGENOM:   HBG730251
- OMA:   VNFIVQK
- PhylomeDB:   Q45499
- ProtClustDB:   CLSK887247
- BioCyc:   BSUB:BSU14670-MONOMER
- BRENDA:   3.1.3.25
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- PANTHER:   PTHR20854
- PRINTS:   PR00377

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.25

Molecular weight: Translated: 29760; Mature: 29629

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: BINDING 69-69 BINDING 185-185 BINDING 214-214

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNWTEIDEIAKKWIREAGARITQSMHESLTIETKSNPNDLVTNIDKETEKFFIDRIQET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCCHHHHHHHHHHHHHH
FPGHRILGEEGQGDKIHSLEGVVWIIDPIDGTMNFVHQQRNFAISIGIFENGEGKIGLIY
CCCCEEECCCCCCCCEEECCCEEEEEECCCHHHHHHHHCCCEEEEEEEEECCCCCEEEEH
DVVHDELYHAFSGRGAYMNETKLAPLKETVIEEAILAINATWVTENRRIDQSVLAPLVKR
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHH
VRGTRSYGSAALELANVAAGRIDAYITMRLAPWDYAAGCVLLNEVGGTYTTIEGEPFTFL
HHCCCCCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEECCCCEEEEECCCCEEEE
ENHSVLAGNPSIHKTIFEEYLHARK
ECCEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNWTEIDEIAKKWIREAGARITQSMHESLTIETKSNPNDLVTNIDKETEKFFIDRIQET
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCCHHHHHHHHHHHHHH
FPGHRILGEEGQGDKIHSLEGVVWIIDPIDGTMNFVHQQRNFAISIGIFENGEGKIGLIY
CCCCEEECCCCCCCCEEECCCEEEEEECCCHHHHHHHHCCCEEEEEEEEECCCCCEEEEH
DVVHDELYHAFSGRGAYMNETKLAPLKETVIEEAILAINATWVTENRRIDQSVLAPLVKR
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHH
VRGTRSYGSAALELANVAAGRIDAYITMRLAPWDYAAGCVLLNEVGGTYTTIEGEPFTFL
HHCCCCCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEECCCCEEEEECCCCEEEE
ENHSVLAGNPSIHKTIFEEYLHARK
ECCEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377